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Title:
POLYMORPH AND APPLICATION OF PYRIMIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/040863
Kind Code:
A1
Abstract:
Provided is a polymorph and application of a pyrimidine derivative and a pharmaceutically acceptable salt thereof. The polymorph and application of the pyrimidine derivative that is an A2A/A2B dual receptor antagonist having the chemical name 3-(4-amino-5-fluoro-6-(1-((6-(2-hydroxypropan-2-yl)pyridin-2-yl)methyl)-1H-1,2,3-triazol-4-yl)pyrimidine-2-yl)-2-methylbenzonitrile and the pharmaceutically acceptable salt thereof.

Inventors:
ZHAO SHUANGNI (CN)
JIANG TAOTAO (CN)
WANG JIBIAO (CN)
TAO TAO (CN)
Application Number:
PCT/CN2022/118594
Publication Date:
March 23, 2023
Filing Date:
September 14, 2022
Export Citation:
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Assignee:
SHANGHAI HAIYAN PHARMACEUTICAL TECH CO LTD (CN)
YANGTZE RIVER PHARM GROUP CO (CN)
International Classes:
C07D401/14; A61K31/444; A61K31/506; A61P35/00; A61P37/00; C07D401/04
Domestic Patent References:
WO2021185256A12021-09-23
WO2020185859A12020-09-17
WO2020205527A12020-10-08
Foreign References:
CN110214012A2019-09-06
CN102892761A2013-01-23
Other References:
J W MULLENS: "Crystallization", 1993, BUTTERWORTH-HEINEMAN LTD.
"CAS", Database accession no. 2239273-34-6
Attorney, Agent or Firm:
ADVANCE CHINA IP LAW OFFICE (CN)
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