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Title:
POLYPEPTIDE COMPOUND FOR PREVENTING AND/OR TREATING RENAL FIBROSIS
Document Type and Number:
WIPO Patent Application WO/2023/169550
Kind Code:
A1
Abstract:
Provided is a polypeptide compound for treating and/or preventing renal fibrosis. The polypeptide compound comprises: a parent peptide represented by Thr-His-His-Arg-Pro-Trp-Thr-NH2; or a polypeptide compound derived from a parent peptide and obtained by carrying on Ala substitution on any amino acid at positions 1-7 in the parent peptide, or carrying out Lys or D-amino acid substantiation on any one amino acid at positions 2-5, or deleting Thr at position 1 and/or His at position 2, or acetylating N-terminus.

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Inventors:
JIANG XIANXING (CN)
YU HUAN (CN)
Application Number:
PCT/CN2023/080721
Publication Date:
September 14, 2023
Filing Date:
March 10, 2023
Export Citation:
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Assignee:
UNIV SUN YAT SEN (CN)
International Classes:
C07K7/06; A61K38/08; A61P13/12
Domestic Patent References:
WO2021041906A12021-03-04
Foreign References:
CN111704653A2020-09-25
US20140057831A12014-02-27
US20200291068A12020-09-17
US20210040151A12021-02-11
Attorney, Agent or Firm:
LECOME INTELLECTUAL PROPERTY AGENT LTD. et al. (CN)
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