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Title:
POLYURETHANE HIGH-MOLECULAR POLYMER HYDROGEL, PREPARATION METHOD THEREFOR, AND APPLICATION
Document Type and Number:
WIPO Patent Application WO/2023/221873
Kind Code:
A1
Abstract:
Provided are a polyurethane high-molecular polymer hydrogel, a preparation method therefor, and an application. The polyurethane high-molecular polymer hydrogel comprises a polyurethane high-molecular polymer and a swelling solvent. Not only does the hydrogel have better biocompatibility and lower toxicity, but after subsequent swelling in water to form the hydrogel, properties such as needle penetration, gelling temperature, 37°C elastic modulus, kinematic viscosity, density, surface tension, light transmittance and refractive index are all more suitable for a vitreous body, and therefore the hydrogel has better replaceability and usage effects when used as a vitreous body substitute.

Inventors:
XIE QIN (CN)
ZHANG YU (CN)
Application Number:
PCT/CN2023/093626
Publication Date:
November 23, 2023
Filing Date:
May 11, 2023
Export Citation:
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Assignee:
ZHEJIANG OCUARMOR MEDTECH CO LTD (CN)
International Classes:
C08J3/075; A61L27/18; C08G18/48
Foreign References:
CN114907584A2022-08-16
CN114907540A2022-08-16
CN111617314A2020-09-04
CN101654508A2010-02-24
KR20090112150A2009-10-28
Other References:
LIU ZENGPING; LIOW SING SHY; LAI SIEW LI; ALLI-SHAIK ASFA; HOLDER GRAHAM E.; PARIKH BHAV HARSHAD; KRISHNAKUMAR SUBRAMANIAN; LI ZIB: "Retinal-detachment repair and vitreous-like-body reformation via a thermogelling polymer endotamponade", NATURE BIOMEDICAL ENGINEERING, NATURE PUBLISHING GROUP UK, LONDON, vol. 3, no. 8, 8 April 2019 (2019-04-08), London , pages 598 - 610, XP036854651, DOI: 10.1038/s41551-019-0382-7
LIU QING-FENG, FENG SHENG-SHAN, XU SHUN-HONG: "Research progress of medical biodegradable polyurethane", CHINA ELASTOMETRICS., vol. 17, no. 4, 25 August 2007 (2007-08-25), pages 63 - 65, XP093108987, DOI: 1005-3174(2007)04-0063-06
Attorney, Agent or Firm:
KANGXIN PARTNERS , P.C. (CN)
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