Title:
POPULATION CLASSIFICATION OF GENETIC DATA SET USING TREE BASED SPATIAL DATA STRUCTURE
Document Type and Number:
WIPO Patent Application WO/2014/024142
Kind Code:
A3
Abstract:
Reference feature vectors are constructed representing reference genetic data sets of a reference population. The reference feature vectors are transformed using a linear transformation to generate reduced dimensionality vector representations of the reference genetic data sets of the reference population. A tree-based spatial data structure is constructed to index the reference genetic data sets as data points defined by at least some dimensions of the reduced dimensionality vector representations of the reference genetic data sets of the reference population. The linear transform may be generated by performing feature reduction on the reference feature vectors. A feature vector representing a proband genetic data set is transformed using the linear transformation to generate a reduced-dimensionality vector representation that is located in the tree-based spatial data structure to perform population assignment for the proband genetic data set.
Inventors:
CHAKRABARTI BISWAROOP (NL)
MUNIYAPPA PRAKASH (NL)
KUMAR SUNIL (NL)
SINGH RANDEEP (NL)
KUMAR SUBODH (NL)
MATTHUR ASHWATHA (NL)
MUNIYAPPA PRAKASH (NL)
KUMAR SUNIL (NL)
SINGH RANDEEP (NL)
KUMAR SUBODH (NL)
MATTHUR ASHWATHA (NL)
Application Number:
PCT/IB2013/056453
Publication Date:
May 15, 2014
Filing Date:
August 07, 2013
Export Citation:
Assignee:
KONINKL PHILIPS NV (NL)
International Classes:
G16B20/20; G06F17/30; G16B20/40; G16B40/00; G16B20/10
Foreign References:
| US20100332210A1 | 2010-12-30 | |||
| US6741983B1 | 2004-05-25 | |||
| US6122628A | 2000-09-19 |
Other References:
P KOTALA ET AL: "Gene Expression Profiling of DNA Microarray Data using Peano Count Trees (P-Trees)", PROCEEDINGS OF THE VIRTUAL CONFERENCE IN GENOMICS AND BIOINFORMATICS, 1 October 2001 (2001-10-01), XP055107792
PRISCILLA R ET AL: "A High-Speed Two Dimensional Hierarchical Clustering of Microarray Gene Expression Data", ADVANCES IN INTELLIGENT AND SOFT COMPUTING,, vol. 132, 1 January 2012 (2012-01-01), pages 539 - 546, XP009176879
PRISCILLA R ET AL: "A High-Speed Two Dimensional Hierarchical Clustering of Microarray Gene Expression Data", ADVANCES IN INTELLIGENT AND SOFT COMPUTING,, vol. 132, 1 January 2012 (2012-01-01), pages 539 - 546, XP009176879
Attorney, Agent or Firm:
STEFFEN, Thomas et al. (AE Eindhoven, NL)
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