PPAR-ACTIVATING COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING SAME

Title:

PPAR-ACTIVATING COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING SAME

Document Type and Number:

WIPO Patent Application WO/2005/023777

Kind Code:

A1

Abstract:

Disclosed is a compound for selectively activating PPAR &agr which is represented by the following general formula (1): (1) (wherein R₁ and R₂ may be the same or different and represent hydrogen atoms or the like; R_3a, R_3b, R_4a and R_4b may be the same or different and represent hydrogen atoms or the like; X represents an oxygen atom or the like; Y represents an oxygen atom, S(O)_l group (l is a number of 0-2), carbonyl group, carbonylamino group, aminocarbonyl group, sulfonylamino group, aminosulfonyl group or NH group; Z represents CH or the like; n is a number of 1-6; and m is a number of 2-6), or a salt thereof. Also disclosed is a pharmaceutical composition containing such a compound.

Inventors:

YAMAZAKI YUKIYOSHI (JP)
TOMA TSUTOMU (JP)
NISHIKAWA MASAHIRO (JP)
OZAWA HIDEFUMI (JP)
OKUDA AYUMU (JP)
ARAKI TAKAAKI (JP)
ABE KAZUTOYO (JP)
ODA SOICHI (JP)

Application Number:

PCT/JP2004/012750

Publication Date:

March 17, 2005

Filing Date:

September 02, 2004

Export Citation:

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Assignee:

KOWA CO (JP)
YAMAZAKI YUKIYOSHI (JP)
TOMA TSUTOMU (JP)
NISHIKAWA MASAHIRO (JP)
OZAWA HIDEFUMI (JP)
OKUDA AYUMU (JP)
ARAKI TAKAAKI (JP)
ABE KAZUTOYO (JP)
ODA SOICHI (JP)

International Classes:

A61K31/4184; A61K31/423; A61K31/428; A61K31/4439; A61P3/06; A61P3/10; A61P9/00; A61P9/10; A61P29/00; C07D263/58; C07D413/02; C07D417/02; (IPC1-7): C07D235/30; C07D263/58; C07D277/82; C07D413/12; C07D498/04; A61K31/4184; A61K31/423; A61K31/424; A61K31/428; A61P3/06; A61P3/10; A61P9/10; A61P9/00; A61P29/00

Domestic Patent References:

WO2002046176A1	2002-06-13
WO2003074495A1	2003-09-12

Foreign References:

JPS50154214A	1975-12-12
JPS51101977A	1976-09-08
JP2004210776A	2004-07-29

Other References: