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Title:
A PREDICTION ALGORITHM FOR DETERMINING THE OPTIMIZED COST-EFFECTIVENESS OF ADVANCED TUMORS TREATMENT
Document Type and Number:
WIPO Patent Application WO/2023/161699
Kind Code:
A1
Abstract:
multivariable cost-effectiveness prediction algorithm is employed for the choice of the type of interventions, therapeutic approach, and therapeutic regimen in severe, chronic, and life-threatening diseases, such as cancer, designed with a precision medicine approach. this algorithm is applicable to advanced diseases with progressive, life-threatening characteristics, limited statistical population, heavy, expensive, chronic therapeutic regimens with low effectiveness and low probability to reach the complete response phase (full recovery), such as malignancies and cancerous tumors. this algorithm is composed of two general parts: effectiveness function and treatment cost function. In the case of a small statistical population in the clinical trials conducted to check the effectiveness of the target drug with precision medicine approach, to increase the population, integrating and expanding the results and clinical data of various trials carried out by the claimed drug, in different cancers, with the commonality in connection with the presence of the claimed biomarker and subsequently

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Inventors:
NIKFAR SHEKOUFEH (IR)
NOSRATI MARZIEH (IR)
ABDOLLAHI MOHAMMAD (IR)
ASFIA MAHDI (IR)
SHARIFNIA MOHAMMADHOSSEIN (IR)
Application Number:
PCT/IB2022/061845
Publication Date:
August 31, 2023
Filing Date:
December 06, 2022
Export Citation:
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Assignee:
NIKFAR SHEKOUFEH (IR)
NOSRATI MARZIEH (IR)
International Classes:
G06Q10/04; G16H20/10; G16H50/30
Foreign References:
US10755816B22020-08-25
Other References:
SHEPARD, D. S.; STASON, W. B.; PERRY, H. M.; CARMEN, B. A.; NAGURNEY, J. T. : "Multivariate Cost-Effectiveness Analysis: An Application to Optimizing Ambulatory Care for Hypertension", INQUIRY, vol. 32, no. 3, 30 November 1994 (1994-11-30), pages 320 - 31, XP009548870, ISSN: 0046-9580
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