Title:
PREDICTION DEVICE, AUTOMATIC CULTURE DEVICE SYSTEM, PREDICTION METHOD, AND KIT
Document Type and Number:
WIPO Patent Application WO/2023/223447
Kind Code:
A1
Abstract:
The present invention provides: a prediction device and prediction method for predicting the future differentiation level of cultured cells before induction of differentiation on the basis of the miRNA content of the exosomes of the cultured cells; a kit; and an automatic cell culture system.
Inventors:
SAITO HIKARU (JP)
HIRAI KAKURO (JP)
KATO MIDORI (JP)
KIYAMA MASAHARU (JP)
HANZAWA HIROKO (JP)
TAKEDA SHIZU (JP)
HIRAI KAKURO (JP)
KATO MIDORI (JP)
KIYAMA MASAHARU (JP)
HANZAWA HIROKO (JP)
TAKEDA SHIZU (JP)
Application Number:
PCT/JP2022/020605
Publication Date:
November 23, 2023
Filing Date:
May 18, 2022
Export Citation:
Assignee:
HITACHI LTD (JP)
International Classes:
C12M1/34; C12M1/00; C12N5/10; C12N15/11; C12N15/113; C12Q1/06; C12Q1/6813; C12Q1/6851
Domestic Patent References:
| WO2018235583A1 | 2018-12-27 |
Foreign References:
| JP2016144439A | 2016-08-12 |
Other References:
SAITO HIKARU; KATO MIDORI; HIRAI KAKURO; KIYAMA MASAHARU; OHYAMA KUNIO; HANZAWA HIROKO; NAKANE ATSUSHI; SEKIYA SAYAKA; YOSHIDA KEN: "Analysis of extracellular vesicles as a potential index for monitoring differentiation of neural lineage cells from induced pluripotent stem cells", JOURNAL OF BIOSCIENCE AND BIOENGINEERING, ELSEVIER, AMSTERDAM, NL, vol. 132, no. 4, 18 July 2021 (2021-07-18), NL , pages 381 - 389, XP086806159, ISSN: 1389-1723, DOI: 10.1016/j.jbiosc.2021.06.004
KATO, MIDORI; NOZAKI, TAKAYUKI; SAITO, HIKARU; HIRAI, KAKURO; KIYAMA, MASAHARU; OHYAMA, KUNIO; HANZAWA, HIROKO; TAKEDA, SHIZU: "Regenerative medicine that enables fundamental treatment and automatic culture technology that supports it", HITACHI HYORON., HITACHI LTD., TOKYO., JP, vol. 102, no. 5, 1 January 2020 (2020-01-01), JP , pages 89 - 94, XP009550582, ISSN: 0367-5874
KATO, MIDORI; NOZAKI, TAKAYUKI; SAITO, HIKARU; HIRAI, KAKURO; KIYAMA, MASAHARU; OHYAMA, KUNIO; HANZAWA, HIROKO; TAKEDA, SHIZU: "Regenerative medicine that enables fundamental treatment and automatic culture technology that supports it", HITACHI HYORON., HITACHI LTD., TOKYO., JP, vol. 102, no. 5, 1 January 2020 (2020-01-01), JP , pages 89 - 94, XP009550582, ISSN: 0367-5874
Attorney, Agent or Firm:
HIRAKI & ASSOCIATES (JP)
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