Title:
PREPARATION FOR LOCAL ADMINISTRATION CONTAINING FLUTICASONE PROPIONATE
Document Type and Number:
WIPO Patent Application WO/2010/052896
Kind Code:
A1
Abstract:
Fluticasone propionate microparticles useful as active ingredients for a preparation for local administration which enables the long-term retention of microparticles of an active ingredient in a mucosa for a long period to achieve a higher therapeutic effect and a higher long-acting property, each of which comprises a fluticasone propionate crystal core and needle-like fluticasone propionate crystals which have been grown radially around the crystal core and which has an average particle size of 10 to 60 μm.
Inventors:
NAGAO TAKESHI (JP)
KAGAMI KAZUHIRO (JP)
OGAWA YASUAKI (JP)
KAGAMI KAZUHIRO (JP)
OGAWA YASUAKI (JP)
Application Number:
PCT/JP2009/005843
Publication Date:
May 14, 2010
Filing Date:
November 04, 2009
Export Citation:
Assignee:
JGC CORP (JP)
NAGAO TAKESHI (JP)
KAGAMI KAZUHIRO (JP)
OGAWA YASUAKI (JP)
NAGAO TAKESHI (JP)
KAGAMI KAZUHIRO (JP)
OGAWA YASUAKI (JP)
International Classes:
C07J31/00; A61K9/107; A61K9/14; A61K31/56; A61P11/00; A61P11/06; A61P11/08; A61P27/16; A61P29/00
Domestic Patent References:
| WO2008126797A1 | 2008-10-23 | |||
| WO2004110585A1 | 2004-12-23 |
Foreign References:
| JP2004067614A | 2004-03-04 | |||
| JP2002533205A | 2002-10-08 | |||
| JP2001502350A | 2001-02-20 |
Other References:
MURNANE, D.: "Crystallization and Crystallinity of Fluticasone Propionate", CRYSTAL GROWTH AND DESIGN, vol. 8, no. 8, 2008, pages 2753 - 2764
Attorney, Agent or Firm:
SIKs & Co. (JP)
Patent business corporation patent firm Sykes (JP)
Patent business corporation patent firm Sykes (JP)
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