Title:
PREPARATION METHOD FOR ACESULFAME POTASSIUM
Document Type and Number:
WIPO Patent Application WO/2022/246861
Kind Code:
A1
Abstract:
A preparation method for acesulfame potassium, comprising: adding triethylamine to a sulfamic acid solution, and carrying out an amination reaction to generate a sulfamic acid ammonium salt solution; adding diketene to the obtained sulfamic acid ammonium salt solution, and under the action of a solid superacid catalyst, carrying out an acylation reaction to obtain an intermediate solution; dissolving sulfur trioxide in a solvent to form a cyclizing agent solution; adding the cyclizing agent solution to the intermediate solution, and carrying out a sulfonation cyclization reaction to obtain a cyclization product solution; adding a hydrolysis agent to the cyclization product solution, and carrying out a hydrolysis reaction to obtain a hydrolysis product solution; and adding a potassium hydroxide solution to the organic phase of the hydrolysis product solution to obtain acesulfame potassium. The method can reduce the impurity content in acesulfame K, thereby making the quality of acesulfame K better, and improve the conversion rate of a raw material, thereby greatly improving the yield of a cyclization product, further improving the yield of a final product, i.e., acesulfame K, and reducing the production costs of acesulfame K.
Inventors:
ZHOU RUI (CN)
DING ZHEN (CN)
CHEN YONGXU (CN)
YANG FENGBAO (CN)
LIU GANG (CN)
DING ZHEN (CN)
CHEN YONGXU (CN)
YANG FENGBAO (CN)
LIU GANG (CN)
Application Number:
PCT/CN2021/097009
Publication Date:
December 01, 2022
Filing Date:
May 28, 2021
Export Citation:
Assignee:
ANHUI JINHE IND CO LTD (CN)
International Classes:
C07D291/06; B01J27/053
Foreign References:
| CN111377882A | 2020-07-07 | |||
| CN104411693A | 2015-03-11 | |||
| CN107868064A | 2018-04-03 | |||
| CN108191790A | 2018-06-22 | |||
| CN112142687A | 2020-12-29 |
Other References:
"Inorganic and Analytical Chemistry Experiments", 28 February 2007, SCIENCE PRESS, CN, ISBN: 9787030231086, article NI, JING'AN ET AL.: "Preparation and Characterization of Solid Superacid", pages: 1 - 3, XP009541340
X. DUAN ET AL.: "Synthesis of Acesulfame Potassium", FINE CHEMICALS, vol. 13, no. 5, 1 January 1996 (1996-01-01), pages 22 - 24, XP055436957, ISSN: 1003-5214, DOI: 10.13550/j .jxhg.1996.05.007
MA QIANLI; SUO YANHUA; MENG FANLONG; ZHANG WEI; WANG YINGJUN: "Research Advance in Modification and Application of SO42-/MxOy Solid Superacid Catalyst", INDUSTRIAL CATALYSIS, NORTHWEST RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA, vol. 22, no. 2, 1 February 2014 (2014-02-01), China , pages 85 - 91, XP009541276, ISSN: 1008-1143, DOI: 10.3969/j.issn.1008-1143.2014.02.002
X. DUAN ET AL.: "Synthesis of Acesulfame Potassium", FINE CHEMICALS, vol. 13, no. 5, 1 January 1996 (1996-01-01), pages 22 - 24, XP055436957, ISSN: 1003-5214, DOI: 10.13550/j .jxhg.1996.05.007
MA QIANLI; SUO YANHUA; MENG FANLONG; ZHANG WEI; WANG YINGJUN: "Research Advance in Modification and Application of SO42-/MxOy Solid Superacid Catalyst", INDUSTRIAL CATALYSIS, NORTHWEST RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA, vol. 22, no. 2, 1 February 2014 (2014-02-01), China , pages 85 - 91, XP009541276, ISSN: 1008-1143, DOI: 10.3969/j.issn.1008-1143.2014.02.002
Attorney, Agent or Firm:
BEIJING LONGAN LAW FIRM (CN)
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