Title:
PREPARATION METHOD FOR BRIVARACETAM
Document Type and Number:
WIPO Patent Application WO/2021/253162
Kind Code:
A1
Abstract:
Provided is a preparation method for brivaracetam. The method has a synthetic route as shown below. The preparation method for the brivaracetam is simple, economical, environmentally friendly and suitable for industrialization.
Inventors:
WANG ZHEN (CN)
KE CHUNLONG (CN)
LIU JUNFENG (CN)
ZHANG PENG (CN)
LI QICHAO (CN)
ZHU GUORONG (CN)
TU YONGJUN (CN)
KE CHUNLONG (CN)
LIU JUNFENG (CN)
ZHANG PENG (CN)
LI QICHAO (CN)
ZHU GUORONG (CN)
TU YONGJUN (CN)
Application Number:
PCT/CN2020/096111
Publication Date:
December 23, 2021
Filing Date:
June 15, 2020
Export Citation:
Assignee:
ZHEJIANG TIANYU PHARMACEUTICAL CO LTD (CN)
International Classes:
C07D207/27; C07C237/06
Domestic Patent References:
| WO2019157856A1 | 2019-08-22 |
Foreign References:
| CN106748950A | 2017-05-31 | |||
| CN108689903A | 2018-10-23 | |||
| CN107652254A | 2018-02-02 | |||
| CN109593055A | 2019-04-09 | |||
| CN108503610A | 2018-09-07 |
Other References:
ARNAUD SCHÜLÉ, ALAIN MERSCHAERT, CHRISTOPHE SZCZEPANIAK, CHRISTOPHE MARÉCHAL, NICOLAS CARLY, JOHN O'ROURKE, CÉLAL ATES: "A Biocatalytic Route to the Novel Antiepileptic Drug Brivaracetam", ORGANIC PROCESS RESEARCH & DEVELOPMENT, AMERICAN CHEMICAL SOCIETY, US, vol. 20, no. 9, 16 September 2016 (2016-09-16), US , pages 1566 - 1575, XP055525783, ISSN: 1083-6160, DOI: 10.1021/acs.oprd.6b00094
ORG. PROCESS RES. DEV., vol. 20, 2016, pages 1566 - 1575
ORG. PROCESS RES. DEV., vol. 20, 2016, pages 1566 - 1575
Attorney, Agent or Firm:
SINO-CREATIVITY INTELLECTUAL PROPERTY LAW FIRM (CN)
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