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Title:
PREPARATION METHOD FOR DRUG LINKER CONJUGATE AND INTERMEDIATE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/231988
Kind Code:
A1
Abstract:
A preparation method for a drug linker conjugate. Provided are a method for preparing the intermediate or the salt thereof, and the use of the intermediate or the salt thereof. The raw materials involved in the preparation method are easy to obtain, the operation is simple, the product purity is high, and the method is suitable for scaled synthesis.

Inventors:
SONG SHUAI (CN)
SHAN AILIN (CN)
CAI JIAQIANG (CN)
LI JUNDONG (CN)
XIAO LIANG (CN)
XUE TONGTONG (CN)
Application Number:
PCT/CN2023/096922
Publication Date:
December 07, 2023
Filing Date:
May 29, 2023
Export Citation:
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Assignee:
MEDILINK THERAPEUTICS SUZHOU CO LTD (CN)
International Classes:
A61K47/68; A61K39/00; C07B37/04; C07K5/083; C07K16/28
Domestic Patent References:
WO2021067861A12021-04-08
WO2021067820A12021-04-08
Foreign References:
CN111936169A2020-11-13
CN111295389A2020-06-16
CN111171041A2020-05-19
CN113766954A2021-12-07
Other References:
DATABASE Registry CAS; 6 December 2015 (2015-12-06), ANONYMOUS : "Carbamic acid, N-[2-[(methoxy methyl)amino]-2-oxoethyl]-, phenylmethyl ester", XP093115847, retrieved from STN Database accession no. 1823314-42-6
Attorney, Agent or Firm:
SHANGHAI BESHINING LAW OFFICE (CN)
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