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Title:
PREPARATION METHOD FOR ERYTHROPOIETIN
Document Type and Number:
WIPO Patent Application WO/2023/040792
Kind Code:
A1
Abstract:
A preparation method for erythropoietin, specifically, a protein separation method. The protein is in contact with two or more cation exchangers, wherein one of the cation exchangers is a fine cation exchanger.

Inventors:
ZHU JIANWEI (CN)
JIANG HUA (CN)
XIE YUEQING (CN)
WANG ZHENYU (CN)
FAN BAOQING (CN)
HAN LEI (CN)
Application Number:
PCT/CN2022/118301
Publication Date:
March 23, 2023
Filing Date:
September 13, 2022
Export Citation:
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Assignee:
JECHO BIOPHARMACEUTICALS CO LTD (CN)
JECHO INST CO LTD (CN)
JECHO LABORATORIES INC (US)
International Classes:
C07K1/18; C12N5/071
Domestic Patent References:
WO2011024024A12011-03-03
Foreign References:
CN1411369A2003-04-16
CN101228185A2008-07-23
CN102076705A2011-05-25
CN103255162A2013-08-21
Other References:
SÁNCHEZ-TRASVIÑA CALEF, FLORES-GATICA MIGUEL, ENRIQUEZ-OCHOA DANIELA, RITO-PALOMARES MARCO, MAYOLO-DELOISA KARLA: "Purification of Modified Therapeutic Proteins Available on the Market: An Analysis of Chromatography-Based Strategies", FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, vol. 9, XP093049742, DOI: 10.3389/fbioe.2021.717326
WU, JIANYONG: "Construction of the Cell Line Chinese Hamster Ovary Expressing High-level Recombinant Darbepoetin Alfa (NESP)", CHINESE MASTER'S DISSERTATIONS FULL- TEXT DATABASE, BASIC SCIENCES, 22 April 2010 (2010-04-22), CN, pages 1 - 53, XP009544648
Attorney, Agent or Firm:
SHANGHAI DIANSHI PARTNERS, P.C. (CN)
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