Title:
PREPARATION METHOD FOR INDIAN BREAD PEEL TRITERPENE COMPOSITION AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2020/155945
Kind Code:
A1
Abstract:
A method for extracting an Indian bread peel composition, comprising: (1) weighing an Indian bread peel sample, adding same to a soaking solvent for soaking, reflowing, and collecting a filtrate; (2) performing vacuum concentration and drying to obtain a crude extract; (3) suspending the crude extract into 1 mol/L NaOH aqueous solution, performing ultrasound for 1 h, and filtering to obtain a crude precipitate; (4) suspending the crude precipitate in water, adding acetic acid for neutralizing until pH is equal to 7, and filtering to obtain a precipitate; and (5) reflowing the precipitate by means of a recrystallization solvent to form a thermal saturation solution, and recrystallizing same to obtain the Indian bread peel composition. The beneficial effect is that: the composition is rich in the content in the Indian bread peel, and can be rapidly prepared. At the same time, the composition has a good application prospect in the preparation of a drug or food for treating diabetes, hyperlipidemia, obesity, and non-alcoholic fatty liver diseases.
Inventors:
LIU HONGWEI (CN)
BAO LI (CN)
CHEN BAOSONG (CN)
ZHANG JINJIN (CN)
BAO LI (CN)
CHEN BAOSONG (CN)
ZHANG JINJIN (CN)
Application Number:
PCT/CN2019/128086
Publication Date:
August 06, 2020
Filing Date:
December 24, 2019
Export Citation:
Assignee:
INST MICROBIOLOGY CAS (CN)
International Classes:
A61K31/575; A61P1/16; A61P3/04; A61P3/06; A61P3/10; A61P5/50
Foreign References:
| CN103550265A | 2014-02-05 |
Other References:
LIU MIAO,WU YUBING: "Research on poria cocos as a homology of medicine and food: current status and future prospects", JOURNAL OF TRADITIONAL CHINESE MEDICINE UNIVERSITY OF HUNAN, vol. 38, no. 12, 31 December 2018 (2018-12-31), DOI: 10.3969/j.issn.1674-070X.2018.12.028
CHANGBO WANG ; YUANYING HUANG: "Study on development of chemical constituent, bioactivity and extraction technology of poria cocos", WORLD SCIENCE AND TECHNOLOGY-MODERNIZATION OF TRADITIONAL CHINESE MEDICINE, vol. 16, no. 7, 31 December 2014 (2014-12-31), pages 1655 - 1663
CHEN HONG-MEI: "Study on extraction technology and antioxidative activity of polysaccharides and triterpenoids from peel of Poria cocos", JOURNAL OF BIOLOGY, vol. 32, no. 2, 30 April 2015 (2015-04-30)
CHANGBO WANG ; YUANYING HUANG: "Study on development of chemical constituent, bioactivity and extraction technology of poria cocos", WORLD SCIENCE AND TECHNOLOGY-MODERNIZATION OF TRADITIONAL CHINESE MEDICINE, vol. 16, no. 7, 31 December 2014 (2014-12-31), pages 1655 - 1663
CHEN HONG-MEI: "Study on extraction technology and antioxidative activity of polysaccharides and triterpenoids from peel of Poria cocos", JOURNAL OF BIOLOGY, vol. 32, no. 2, 30 April 2015 (2015-04-30)
Attorney, Agent or Firm:
BEIJING LAWSING IP FIRM (CN)
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