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Title:
PREPARATION METHOD FOR AND INTERMEDIATE OF PYRROLO SIX-MEMBERED HETEROAROMATIC RING DERIVATIVE
Document Type and Number:
WIPO Patent Application WO/2018/095320
Kind Code:
A1
Abstract:
Disclosed are an intermediate of a pyrrolo six-membered heteroaromatic ring derivative as a JAK inhibitor and a preparation method therefor, and a method for preparing a pyrrolo six-membered heteroaromatic ring derivative using the intermediate. The method improves the reaction yield, is simple and easy to operate and control, and is conducive to expanded industrial production.

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Inventors:
LIU BING (CN)
BIAN LIN (CN)
GAO XIAOHUI (CN)
Application Number:
PCT/CN2017/112237
Publication Date:
May 31, 2018
Filing Date:
November 22, 2017
Export Citation:
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Assignee:
JIANGSU HENGRUI MEDICINE CO (CN)
International Classes:
C07D487/04; A61K31/519; A61P19/02; A61P29/00
Domestic Patent References:
WO2009054941A12009-04-30
WO2002000661A12002-01-03
WO2001042246A22001-06-14
WO2001042246A22001-06-14
WO2002000661A12002-01-03
WO2009054941A12009-04-30
WO2011013785A12011-02-03
WO2013091539A12013-06-27
WO2014194741A12014-12-11
WO2008089636A12008-07-31
Foreign References:
CN103415520A2013-11-27
CN104470927A2015-03-25
CN102510865A2012-06-20
Other References:
See also references of EP 3543241A4
Attorney, Agent or Firm:
GE CHENG & CO., LTD. (CN)
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