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Title:
PREPARATION METHOD FOR NK CELLS HAVING LOW EXPRESSION OF CD7
Document Type and Number:
WIPO Patent Application WO/2022/188764
Kind Code:
A1
Abstract:
Disclosed is a preparation method for NK cells having low expression of CD7. The NK cells obtained according to the preparation method in the present invention achieve low expression of CD7, and a suicide phenomenon of cells can be avoided after the NK cells are introduced into CAR targeting CD7, so that the NK cells have a higher clinical application value.

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Inventors:
LI JIANQIANG (CN)
LIU YING (CN)
Application Number:
PCT/CN2022/079661
Publication Date:
September 15, 2022
Filing Date:
March 08, 2022
Export Citation:
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Assignee:
HEBEI SENLANG BIOTECHNOLOGY CO LTD (CN)
International Classes:
A61K39/00; C12N5/0783; A61P35/00; A61P35/02; A61P37/02; C07K19/00; C12N5/078; C12N5/10; C12N15/62
Foreign References:
CN112980788A2021-06-18
AU2015271985A12016-01-21
CN108624559A2018-10-09
CN111394310A2020-07-10
CN111235105A2020-06-05
JP2014227418A2014-12-08
CN111500535A2020-08-07
CN112251406A2021-01-22
US20160097035A12016-04-07
Attorney, Agent or Firm:
BEIJING PREINTELL IP CO., LTD (CN)
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