Title:
PREPARATION METHOD FOR SYNTHETASE FOR CONTINUOUS BLOOD GLUCOSE MONITORING
Document Type and Number:
WIPO Patent Application WO/2024/103490
Kind Code:
A1
Abstract:
A preparation method for a synthetase for continuous blood glucose monitoring, comprising the preparation steps of: step S1, hydroxylating glass beads; step S2, silanizing the glass beads; step S3, combining the glass beads with glucose; step S4, synthesizing polymer particles on the surfaces of the glass beads to form a glucose synthetase; and step S5, separating the high-specificity glucose synthetase. The surfaces of the glass beads are activated, and the glass beads are combined with glucose, and then are combined with a polymer to form a glucose synthetase. The artificial synthetase prepared by the method has low sensitivity to the temperature and the pH value, is less affected, and can be directly used in a blood glucose electrochemical sensor.
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Inventors:
ZHANG SHAODA (CN)
QIU ZHIPENG (CN)
ZHENG XINGYU (CN)
QIU ZHIPENG (CN)
ZHENG XINGYU (CN)
Application Number:
PCT/CN2022/141238
Publication Date:
May 23, 2024
Filing Date:
December 23, 2022
Export Citation:
Assignee:
SHENZHEN COFOE BIOTECHNOLOGY CO LTD (CN)
International Classes:
G01N27/30; B01J31/06; C08G75/045
Domestic Patent References:
| WO2020117170A1 | 2020-06-11 |
Foreign References:
| US20040191882A1 | 2004-09-30 | |||
| CN101832997A | 2010-09-15 | |||
| CN109270143A | 2019-01-25 | |||
| CN114609208A | 2022-06-10 | |||
| CN114778634A | 2022-07-22 |
Attorney, Agent or Firm:
SHENZHEN YUANHANG INTELLECTUAL PROPERTY OFFICE (GENERAL PARTNER) (CN)
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