Title:
PREPARATION AND THERAPEUTIC USE OF 3D-CULTURED FIBROBLASTS
Document Type and Number:
WIPO Patent Application WO/2024/077295
Kind Code:
A3
Abstract:
The present disclosure provides methods, compositions, and systems for producing and using organoids comprising fibroblasts. The organoids can be generated and placed in a particular storage matrix which allows for sufficient conditions for transport and reduces damage to cells in the organoids compared to known media. The organoids may be utilized for extended release of the fibroblasts for cell therapy and also for drug delivery at a target site following administration to an individual in need thereof.
Inventors:
JIANG BIN (US)
KHOJA HAMID (US)
O'HEERON PETE (US)
KHOJA HAMID (US)
O'HEERON PETE (US)
Application Number:
PCT/US2023/076365
Publication Date:
May 16, 2024
Filing Date:
October 09, 2023
Export Citation:
Assignee:
FIBROBIOLOGICS (US)
International Classes:
C12N5/077; A61K35/33; C12N5/02
Attorney, Agent or Firm:
SISTRUNK, Melissa L. (US)
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