Title:
PROBIOTIC STRAIN FOR UPPER RESPIRATORY TRACT INFECTION, STRESS, ANXIETY, MEMORY AND COGNITIVE DYSFUNCTIONS, AND AGEING
Document Type and Number:
WIPO Patent Application WO/2020/050553
Kind Code:
A1
Abstract:
The present invention relates to Accordingly, a first aspect of the invention relates to a strain of Lactobacillus plantarum deposited in the China General Microbiological Culture Collection Centre (CGMCC) under the accession number CGMCC 15535 and full genome sequence deposited in GenBank under accession number CP031318. The strain is particularly beneficial for upper respiratory tract infection, stress, anxiety, memory and cognitive dysfunctions, Alzheimer's disease, hyperlipidemia, gut balance and ageing.
Inventors:
PARK YONG-HA (KR)
Application Number:
PCT/KR2019/011130
Publication Date:
March 12, 2020
Filing Date:
August 30, 2019
Export Citation:
Assignee:
CLINICAL NUTRITION INTL M SDN BHD (MY)
LII RUN SDN BHD (MY)
LII RUN SDN BHD (MY)
International Classes:
C12N1/20; A61K31/19; A61K31/192; A61K35/00; A61K35/747; A61P1/16; A61P3/06; A61P11/00; A61P25/28; C12R1/25
Foreign References:
| US20170251710A1 | 2017-09-07 | |||
| KR100654427B1 | 2006-12-06 |
Other References:
LACTOBACILLUS PLANTARUM DR7 FOR GUT-BRAIN-AXIS BENEFITS (DR7), 3 July 2018 (2018-07-03), XP055692979, Retrieved from the Internet
MALLIKARJUNA, N. ET AL.: "Role of Lactobacillus plantarum MTCC1325 in membrane-bound transport ATPases system in Alzheimer' s disease-induced rat brain", BIOLMPACTS, vol. 6, no. 4, 2016, pages 203 - 209, XP055508497, DOI: 10.15171/bi.2016.27
PREMA, P. ET AL.: "Production and characterization of an antifungal compound (3-phenyllactic acid) produced by Lactobacillus plantarum strain", FOOD AND BIOPROCESS TECHNOLOGY, vol. 3, 8 August 2008 (2008-08-08), pages 379 - 386, XP055692981
PARK, B. ET AL.: "Identification of 2-hydroxyisocaproic acid production in lactic acid bacteria and evaluation of microbial dynamics during kimchi ripening", SCIENTIFIC REPORTS, vol. 7, 10904, 7 September 2017 (2017-09-07), pages 1 - 8, XP055692988
CHONG, H.-X. ET AL.: "Lactobacillus plantarum DR7 improved upper respiratory tract infections via enhancing immune and inflammatory parameters: A randomized, double-blind, placebo-controlled study", JOURNAL OF DAIRY SCIENCE, vol. 102, 4 April 2019 (2019-04-04), pages 4783 - 4797, XP085686901, DOI: 10.3168/jds.2018-16103
MALLIKARJUNA, N. ET AL.: "Role of Lactobacillus plantarum MTCC1325 in membrane-bound transport ATPases system in Alzheimer' s disease-induced rat brain", BIOLMPACTS, vol. 6, no. 4, 2016, pages 203 - 209, XP055508497, DOI: 10.15171/bi.2016.27
PREMA, P. ET AL.: "Production and characterization of an antifungal compound (3-phenyllactic acid) produced by Lactobacillus plantarum strain", FOOD AND BIOPROCESS TECHNOLOGY, vol. 3, 8 August 2008 (2008-08-08), pages 379 - 386, XP055692981
PARK, B. ET AL.: "Identification of 2-hydroxyisocaproic acid production in lactic acid bacteria and evaluation of microbial dynamics during kimchi ripening", SCIENTIFIC REPORTS, vol. 7, 10904, 7 September 2017 (2017-09-07), pages 1 - 8, XP055692988
CHONG, H.-X. ET AL.: "Lactobacillus plantarum DR7 improved upper respiratory tract infections via enhancing immune and inflammatory parameters: A randomized, double-blind, placebo-controlled study", JOURNAL OF DAIRY SCIENCE, vol. 102, 4 April 2019 (2019-04-04), pages 4783 - 4797, XP085686901, DOI: 10.3168/jds.2018-16103
Attorney, Agent or Firm:
KIM, Youngrok (KR)
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