Title:
PROCESS FOR THE PREPARATION OF GABAPENTIN
Document Type and Number:
WIPO Patent Application WO2005092837
Kind Code:
A3
Abstract:
The present invention relates to a process for the preparation of gabapentin and, more particularly, it relates to a precipitation process of gabapentin by acidification of an aqueous solution deriving from the Hofmann rearrangement of 1,1-cyclohexanediacetic acid monoamide.
Inventors:
GIOVANETTI ROBERTO (IT)
NICOLI ANDREA (IT)
VERZINI MASSIMO (IT)
SORIATO GIORGIO (IT)
COTARCA LIVIUS (IT)
NICOLI ANDREA (IT)
VERZINI MASSIMO (IT)
SORIATO GIORGIO (IT)
COTARCA LIVIUS (IT)
Application Number:
PCT/EP2005/051297
Publication Date:
December 22, 2005
Filing Date:
March 21, 2005
Export Citation:
Assignee:
ZAMBON SPA (IT)
GIOVANETTI ROBERTO (IT)
NICOLI ANDREA (IT)
VERZINI MASSIMO (IT)
SORIATO GIORGIO (IT)
COTARCA LIVIUS (IT)
GIOVANETTI ROBERTO (IT)
NICOLI ANDREA (IT)
VERZINI MASSIMO (IT)
SORIATO GIORGIO (IT)
COTARCA LIVIUS (IT)
International Classes:
C07C227/04; C07C227/40; C07C227/42; C07C229/28; (IPC1-7): C07C227/40; C07C229/28
Domestic Patent References:
| WO2002034709A1 | 2002-05-02 | |||
| WO2003089403A1 | 2003-10-30 | |||
| WO2004110981A1 | 2004-12-23 |
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