Title:
PROCESS FOR THE PREPARATION OF A GRANULAR MICROBIAL BIOMASS AND ISOLATION OF VALUABLE COMPOUNDS THEREFROM
Document Type and Number:
WIPO Patent Application WO1997036996
Kind Code:
A3
Abstract:
A process for the isolation of desired compound(s) from a microbial biomass is diclosed, wherein the microbial biomass (which, if necessary, is pretreated to give a dry matter content of from 25 to 80 %) is granulated (e.g. by extrusion) and then dried to a dry matter content of at least 80 %. The granulation of the biomass to granules significantly eases subsequent drying of the biomass (which can be stored as dried granules) and gives higher yields on extraction of the compound(s).
Inventors:
BIJL HENDRIK LOUIS (NL)
SCHAAP ALBERT (NL)
VISSER JOHANNES MARTINUS JACOB (NL)
SCHAAP ALBERT (NL)
VISSER JOHANNES MARTINUS JACOB (NL)
Application Number:
PCT/EP1997/001446
Publication Date:
January 22, 1998
Filing Date:
March 21, 1997
Export Citation:
Assignee:
GIST BROCADES BV (NL)
BIJL HENDRIK LOUIS (NL)
SCHAAP ALBERT (NL)
VISSER JOHANNES MARTINUS JACOB (NL)
BIJL HENDRIK LOUIS (NL)
SCHAAP ALBERT (NL)
VISSER JOHANNES MARTINUS JACOB (NL)
International Classes:
A23D9/00; A23K1/16; A23L1/28; A23L1/30; A23L33/00; A23L33/15; A61K8/37; A61K8/67; A61K8/92; A61K8/97; A61K8/99; A61Q19/00; C07C51/47; C11B1/02; C11B1/10; C12N1/00; C12N1/12; C12N1/14; C12P7/64; C12P17/06; C12P19/42; C12P23/00; (IPC1-7): C12N1/12; C12N1/14; C12P7/64; C12N1/00
Domestic Patent References:
| WO1994029292A1 | 1994-12-22 | |||
| WO1993020183A1 | 1993-10-14 | |||
| WO1992012711A1 | 1992-08-06 | |||
| WO1991011918A1 | 1991-08-22 |
Foreign References:
| GB1466853A | 1977-03-09 | |||
| FR2210662A1 | 1974-07-12 | |||
| DD150627A1 | 1981-09-09 | |||
| DE1923529A1 | 1969-12-04 | |||
| EP0688871A2 | 1995-12-27 | |||
| EP0322227A2 | 1989-06-28 | |||
| US4056638A | 1977-11-01 |
Other References:
JAREONKITMONGKOL S ET AL: "PRODUCTION OF DIHOMO-GAMMA-LINOLENIC ACID BY A DELTA-5 DESATURASE-DEFECTIVE MUTANT OF MORTIERELLA-ALPINA 1S-4", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 58 (7). 1992. 2196-2200., XP000676362
JAREONKITMONGKOL S ET AL: "PRODUCTION OF AN EICOSAPENTAENOIC ACID-CONTAINING OIL BY A DELTA-12 DESATURASE-DEFECTIVE MUTANT OF MORTIERELLA-ALPINA 1S-4", JOURNAL OF THE AMERICAN OIL CHEMISTS' SOCIETY, 70 (2). 1993. 119-123., XP000676339
DATABASE WPI Week 9210, Derwent World Patents Index; AN 92-077323, XP002035614
KYLE D J; RATLEDGE C ED.: "Industrial applications of single cell oils.", 1992, AMERICAN OIL CHEMISTS SOCIETY, CHAMPAIGN, XP002044902
JAREONKITMONGKOL S ET AL: "PRODUCTION OF AN EICOSAPENTAENOIC ACID-CONTAINING OIL BY A DELTA-12 DESATURASE-DEFECTIVE MUTANT OF MORTIERELLA-ALPINA 1S-4", JOURNAL OF THE AMERICAN OIL CHEMISTS' SOCIETY, 70 (2). 1993. 119-123., XP000676339
DATABASE WPI Week 9210, Derwent World Patents Index; AN 92-077323, XP002035614
KYLE D J; RATLEDGE C ED.: "Industrial applications of single cell oils.", 1992, AMERICAN OIL CHEMISTS SOCIETY, CHAMPAIGN, XP002044902
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