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Title:
PROCESS FOR PRODUCING CAROTENOID COMPOUND
Document Type and Number:
WIPO Patent Application WO/2005/028661
Kind Code:
A1
Abstract:
A process for producing zeaxanthin, β-carotene or lycopene which comprises mutagenizing a carotenoid-producing microorganism the DNA base sequence of which corresponding to 16S ribosomal RNA is substantially homologous with the base sequence represented by SEQ ID NO:1, selecting a mutant showing a high ratio of zeaxanthin, β-carotene or lycopene in the total carotenoid yield to thereby obtain a zeaxanthin, β-carotene or lycopene-producing strain, culturing the mutant, and then harvesting zeaxanthin, β-carotene or lycopene or a carotenoid mixture containing the same from the thus obtained culture.

Inventors:
TSUBOKURA AKIRA (JP)
YONEDA HISASHI (JP)
HIRASAWA KAZUAKI (JP)
Application Number:
PCT/JP2004/013033
Publication Date:
March 31, 2005
Filing Date:
September 08, 2004
Export Citation:
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Assignee:
NIPPON OIL CORP (JP)
TSUBOKURA AKIRA (JP)
YONEDA HISASHI (JP)
HIRASAWA KAZUAKI (JP)
International Classes:
A23L1/275; A23L1/30; C09B61/00; C12N15/01; C12P23/00; (IPC1-7): C12P23/00; A23L1/275; A23L1/30
Domestic Patent References:
WO2001096591A12001-12-20
Foreign References:
JPH09308481A1997-12-02
JP2001095500A2001-04-10
JPH089964A1996-01-16
JPH0779796A1995-03-28
JP2001512030A2001-08-21
JP2003304875A2003-10-28
JPH0892205A1996-04-09
Other References:
TSUBOKURA, A. ET AL.: "Paracoccus carotinifaciens sp. nov., a new aerobic gram-negative astaxanthin-producing bacterium", INT. J SYST. BACTERIOL., vol. 49, no. 1, 1999, pages 277 - 282, XP002962170
HARKER, M. ET AL.: "Paracoccus marcusii sp. nov., an orange gram-negative coccus", INT. J SYST. BACTERIOL., vol. 48, no. 2, 1998, pages 543 - 548, XP002983667
TRIPATHI, U. ET AL.: "Studies on Haematococcus pluvialis for improved production of astaxanthin by mutagenesis", WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY, vol. 17, no. 2, 2001, pages 143 - 148, XP002983668
FISHERIES, SCIENCE, vol. 62, no. 1, 1996, pages 134 - 137
BIOL. PHAIM. BULL., vol. 18, no. 2, 1995, pages 227 - 233
FOOD STYLE 21, vol. 3, no. 3, 1999, pages 50 - 53
BIOL. PHARM. BULL., vol. 18, no. 2, 1995, pages 227 - 233
PURE APPL. CHEM., vol. 63, no. 1, 1991, pages 45
Attorney, Agent or Firm:
Hiraki, Yusuke (3-20 Toranomon 4-chom, Minato-ku Tokyo 01, JP)
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