Title:
PROCESS FOR PRODUCING RADIOACTIVE FLUORINE COMPOUND
Document Type and Number:
WIPO Patent Application WO/2005/030677
Kind Code:
A1
Abstract:
A process for producing a radioactive fluorine compound which comprises a step in which [18O] water containing [18F] fluoride ions is introduced into a column packed with an ion-exchange resin to collect the [18F] fluoride ions and a step in which a substrate is reacted with the [18F] fluoride ions collected, characterized in that the ion-exchange resin is a resin represented by the following general formula (1): (1) (wherein n is an integer of 1 to 10; R represents a linear or branched, C1-8 monovalent hydrocarbon group; P represents a styrene-based copolymer; and Y represents an anion).
Inventors:
ITO OSAMU (JP)
HIRANO KEIICHI (JP)
MORITA TAKESHI (JP)
KUROSAKI FUMIE (JP)
HIRANO KEIICHI (JP)
MORITA TAKESHI (JP)
KUROSAKI FUMIE (JP)
Application Number:
PCT/JP2004/014184
Publication Date:
April 07, 2005
Filing Date:
September 28, 2004
Export Citation:
Assignee:
NIHON MEDIPHYSICS CO LTD (JP)
ITO OSAMU (JP)
HIRANO KEIICHI (JP)
MORITA TAKESHI (JP)
KUROSAKI FUMIE (JP)
ITO OSAMU (JP)
HIRANO KEIICHI (JP)
MORITA TAKESHI (JP)
KUROSAKI FUMIE (JP)
International Classes:
C07B59/00; C07C211/63; C07H5/02; (IPC1-7): C07B59/00; C07C29/62; C07C31/20; C07C227/16; C07C229/36; C07C229/48; C07H5/02
Domestic Patent References:
| WO2004082828A1 | 2004-09-30 | |||
| WO2003002157A1 | 2003-01-09 | |||
| WO2002084402A2 | 2002-10-24 |
Foreign References:
| JPH07507813A | 1995-08-31 | |||
| JPH11508923A | 1999-08-03 | |||
| JPH11295494A | 1999-10-29 | |||
| JPH08325169A | 1996-12-10 | |||
| JPH08325168A | 1996-12-10 | |||
| EP0798307A1 | 1997-10-01 |
Other References:
CHEMICAL ABSTRACTS, vol. 28, no. 6, 1977, Columbus, Ohio, US; abstract no. 167671C, DE KLEIJN J.P. ET AL.: "labeling with reactor produced fluorine-18. III. POlymer supported fluorine-18 as a fluorinating agent" page 591-594; XP002984238
CHEMICAL ABSTRACTS, vol. 49, no. 4, 1998, Columbus, Ohio, US; abstract no. 128:270780, OHSAKI K. ET AL.: "Polymer-supported catalysts for efficient on-column preparation of 2-deoxy-2-[18F]fluoro-D-glucose" page 373-378; XP002984239
CHEMICAL ABSTRACTS, vol. 49, no. 4, 1998, Columbus, Ohio, US; abstract no. 128:270780, OHSAKI K. ET AL.: "Polymer-supported catalysts for efficient on-column preparation of 2-deoxy-2-[18F]fluoro-D-glucose" page 373-378; XP002984239
Attorney, Agent or Firm:
Asamura, Kiyoshi (New Ohtemachi Bldg. 2-1, Ohtemachi 2-chom, Chiyoda-ku Tokyo, JP)
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