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Title:
PROCESS FOR PRODUCING SUCCINIC ACID
Document Type and Number:
WIPO Patent Application WO/2005/021770
Kind Code:
A1
Abstract:
Either a microorganism which has been modified so as to have enhanced fumarate reductase activity or a product of treatment of the microorganism is caused to act on an organic raw material in a reaction liquid containing carbonate ions, hydrogen carbonate ions, or carbon dioxide gas to generate succinic acid. Preferably, either a microorganism which has been modified so as to have enhanced fumarate reductase activity, enhanced pyruvate carboxylase activity, and reduced lactate dehydrogenase activity or a product of treatment of the microorganism is caused to act on an organic raw material in a reaction liquid containing carbonate ions, hydrogen carbonate ions, or carbon dioxide gas to generate succinic acid. The succinic acid thus generated is recovered to produce succinic acid.

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Inventors:
MURASE MAKOTO (JP)
AOYAMA RYUSUKE (JP)
IKUTA MIKI (JP)
YAMAGISHI KENJI (JP)
MORIYA MIKA (JP)
NAKAMURA JUN (JP)
KOJIMA HIROYUKI (JP)
Application Number:
PCT/JP2004/012404
Publication Date:
March 10, 2005
Filing Date:
August 27, 2004
Export Citation:
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Assignee:
MITSUBISHI CHEM CORP (JP)
AJINOMOTO KK (JP)
MURASE MAKOTO (JP)
AOYAMA RYUSUKE (JP)
IKUTA MIKI (JP)
YAMAGISHI KENJI (JP)
MORIYA MIKA (JP)
NAKAMURA JUN (JP)
KOJIMA HIROYUKI (JP)
International Classes:
C12N1/21; C12N15/09; C12P7/40; C12P7/46; (IPC1-7): C12P7/40; C12N1/21; C12N15/09
Foreign References:
JPH11196887A1999-07-27
JP2002291477A2002-10-08
JP2001190297A2001-07-17
JP2002511250A2002-04-16
JP2000500333A2000-01-18
JP2003235593A2003-08-26
JP2003235592A2003-08-26
JP2001514900A2001-09-18
US5142834A1992-09-01
US5504004A1996-04-02
JPH11113588A1999-04-27
JPH11196888A1999-07-27
JPH11196887A1999-07-27
JPH03210184A1991-09-13
JPH0272876A1990-03-13
US5185262A1993-02-09
JPH01191686A1989-08-01
JPS5867679A1983-04-22
JPS5877895A1983-05-11
JPS58192900A1983-11-10
JPS57134500A1982-08-19
JPS5835197A1983-03-01
JPS57183799A1982-11-12
JPH10215883A1998-08-18
JPH11206385A1999-08-03
JPH11196888A1999-07-27
Other References:
See also references of EP 1672077A4
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Attorney, Agent or Firm:
Kawaguchi, Yoshiyuki (Higashi Nihonbashi 3-chome Chuo-ku, Tokyo 04, JP)
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