PROCESS FOR PRODUCING SULFONE DERIVATIVE

WIPO Patent Application WO/2002/074762

A1

A process for producing a sulfone derivative represented by the general formula R-W-S(O)¿2?-X-Y-L?2¿ (IIIa) (wherein R represents an optionally substituted cyclic hydrocarbon group, etc.; W represents a bond or an optionally substituted divalent chain hydrocarbon group; X represents an optionally substituted divalent chain hydrocarbon group; Y represents -N(R?5¿)-, -CO-, -S(O)-, -S(O)¿2?-, -CH¿2?-, or a bond; and L?2¿ represents hydrogen, hydroxy, or optionally substituted alkoxy) or a salt thereof, characterized by reacting a sulfinic acid derivative represented by the general formula R-W-S(O)¿2?-M (I) (wherein R and W are the same as defined above; and M represents hydrogen, an alkali metal, or an alkaline earth metal) or a salt thereof with a compound represented by the general formula L?1¿-X-Y-L?2¿ (IIa) (wherein X, Y, and L?2¿ are the same as defined above; L?1¿ represents a leaving group; and R?5¿ represents hydrogen, etc.) or a salt thereof.

MIZUFUNE HIDEYA (JP)
YAMAMOTO HIROAKI (JP)
MIKI SHOKYO (JP)

PCT/JP2002/002323

September 26, 2002

March 13, 2002

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TAKEDA CHEMICAL INDUSTRIES LTD (JP)
MIZUFUNE HIDEYA (JP)
YAMAMOTO HIROAKI (JP)
MIKI SHOKYO (JP)

C07C315/00; C07D401/04; C07C317/44; (IPC1-7): C07D401/04; C07C315/00; C07C317/44

WO2002006234A1	2002-01-24
WO1996010022A1	1996-04-04
WO1995028420A1	1995-10-26
WO2001066541A1	2001-09-13
WO1994022826A1	1994-10-13
WO1997036899A1	1997-10-09

JPS5942359A	1984-03-08
EP0619303A1	1994-10-12
JPH0748341A	1995-02-21
JPH0525119A	1993-02-02
GB1381570A	1975-01-22
JP2000178247A	2000-06-27
EP0008014A1	1980-02-20

Takahashi, Shuichi c/o Osaka Plant of TAKEDA CHEMICAL INDUSTRIES (LTD. 17-85 Jusohonmachi 2-chom, Yodogawa-ku Osaka-shi Osaka, JP)

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