Title:
PROCESS FOR PRODUCING TRANS-2-BROMOINDAN-1-OL
Document Type and Number:
WIPO Patent Application WO/1996/028406
Kind Code:
A1
Abstract:
An industrial process for producing trans-2-bromoindan-1-ol at a low cost. The trans-2-bromoindan-1-ol of formula (II) can be produced by hydrolyzing 1,2-dibromoindan of general formula (I), (wherein the relative configuration of two bromine atoms at the 1- and 2-positions may be either trans or cis). Alternatively, the compound of the formula (II) can be produced also by brominating indene into 1,2-dibromoindan and hydrolyzing the reaction mixture of the bromination continuously without the isolation of 1,2-dibromoindan. 1,2-Dibromoindan can be produced also by reacting indene with hydrogen bromide in the presence of hydrogen peroxide.
Inventors:
IGARASHI YOSHIO (JP)
NAKANO SHIGERU (JP)
KONNO YUZI (JP)
ASANO FUMIHIRO (JP)
NAKANO SHIGERU (JP)
KONNO YUZI (JP)
ASANO FUMIHIRO (JP)
Application Number:
PCT/JP1996/000619
Publication Date:
September 19, 1996
Filing Date:
March 13, 1996
Export Citation:
Assignee:
ICHIKAWA GOSEI KAGAKU KK (JP)
IGARASHI YOSHIO (JP)
NAKANO SHIGERU (JP)
KONNO YUZI (JP)
ASANO FUMIHIRO (JP)
IGARASHI YOSHIO (JP)
NAKANO SHIGERU (JP)
KONNO YUZI (JP)
ASANO FUMIHIRO (JP)
International Classes:
C07C17/02; C07C29/124; C07C35/23; C07C29/58; (IPC1-7): C07C35/52; C07C29/124; C07C23/18; C07C17/08
Foreign References:
| JPH07316106A | 1995-12-05 |
Other References:
ACTA CRYST. SEC. C., Vol. 50, (1994), L. BENMENNI, p. 1636-1638.
J. ORG. CHEM., Vol. 37, No. 20, (1972), A. GAGIS, p. 3181-3182.
J. CHEM. SOC. PERKIN TRANS 2, (1991), DALE F. SHELLHAMER, p. 401-403.
SYNTHESIS, (1977), T. HO, p. 676-677.
J. ORG. CHEM., Vol. 45, No. 23, (1980), W.E. BILLUPS, p. 4636-4641.
J. ORG. CHEM. Vol. 45, No. 25, (1980), G.E. HEASLEY, p. 5150-5155.
J. AM. CHEM. SOC., Vol. 118, No. 2, 17 January 1996, M.R. DETTY, p. 313-318.
J. AM. CHEM. SOC., Vol. 117, No. 1, 11 January 1995, D.T. SAWYER, p. 106-109.
J. ORG. CHEM., Vol. 37, No. 20, (1972), A. GAGIS, p. 3181-3182.
J. CHEM. SOC. PERKIN TRANS 2, (1991), DALE F. SHELLHAMER, p. 401-403.
SYNTHESIS, (1977), T. HO, p. 676-677.
J. ORG. CHEM., Vol. 45, No. 23, (1980), W.E. BILLUPS, p. 4636-4641.
J. ORG. CHEM. Vol. 45, No. 25, (1980), G.E. HEASLEY, p. 5150-5155.
J. AM. CHEM. SOC., Vol. 118, No. 2, 17 January 1996, M.R. DETTY, p. 313-318.
J. AM. CHEM. SOC., Vol. 117, No. 1, 11 January 1995, D.T. SAWYER, p. 106-109.
Download PDF:
Previous Patent: PROCESS FOR PRODUCING 1,2-ETHANEDIOL DERIVATIVES
Next Patent: PROCESS FOR THE ALKOXYLATION OF FLUORINATED ALCOHOLS
Next Patent: PROCESS FOR THE ALKOXYLATION OF FLUORINATED ALCOHOLS