Title:
PROCESS FOR PRODUCTION OF 1β-METHYLCARBAPENEM
Document Type and Number:
WIPO Patent Application WO/2007/116724
Kind Code:
A1
Abstract:
Disclosed is a novel process for producing a 1β-methylcarbapenem compound by culturing a microorganism. A 1β-methylcarbapenem compound can be produced by culturing a microorganism capable of producing a carbapenem compound, particularly a thienamycin-producing microorganism, in a culture medium supplemented with a (2S,4S)-4-methylglutamic acid analogue and isolating the 1β-methylcarbapenem compound from the culture. The 1β-methylcarbapenem compound is useful as a pharmaceutical agent or a raw material for a pharmaceutical agent.
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Inventors:
SASAKI TAKAYUKI (JP)
TANI MASATO (JP)
TAMURA TAKAYOSHI (JP)
TANI MASATO (JP)
TAMURA TAKAYOSHI (JP)
Application Number:
PCT/JP2007/056336
Publication Date:
October 18, 2007
Filing Date:
March 27, 2007
Export Citation:
Assignee:
MEIJI SEIKA KAISHA (JP)
SASAKI TAKAYUKI (JP)
TANI MASATO (JP)
TAMURA TAKAYOSHI (JP)
SASAKI TAKAYUKI (JP)
TANI MASATO (JP)
TAMURA TAKAYOSHI (JP)
International Classes:
C12P37/00; C12R1/465
Foreign References:
| JPS58152476A | 1983-09-10 | |||
| JPH0751092A | 1995-02-28 | |||
| JPH07196660A | 1995-08-01 |
Attorney, Agent or Firm:
YOSHITAKE, Kenji et al. (Room 323 Fuji Bldg., 2-3,Marunouchi 3-chom, Chiyoda-ku Tokyo 05, JP)
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