Title:
A PROCESS FOR STEREOSELECTIVE SYNTHESIS OF LAMIVUDINE
Document Type and Number:
WIPO Patent Application WO/2008/141485
Kind Code:
A1
Abstract:
A process for stereoselective synthesis of lamivudine, comprising (a) glycosylation of compounds of formula (I) and cytosine or protected cytosine, separating the resulting products by crystallization to afford intermediates of formula (II); (b) removing the protecting groups of intermediates of formula (II) to obtain lamivudine.
Inventors:
LI JINLIANG (CN)
LV FENG (CN)
LV FENG (CN)
Application Number:
PCT/CN2007/002038
Publication Date:
November 27, 2008
Filing Date:
June 29, 2007
Export Citation:
Assignee:
SHANGHAI DESANO PHARMACEUTICAL (CN)
SHANGHAI DESANO CHEMICAL PHARM (CN)
LI JINLIANG (CN)
LV FENG (CN)
SHANGHAI DESANO CHEMICAL PHARM (CN)
LI JINLIANG (CN)
LV FENG (CN)
International Classes:
C07D411/04; C07D327/04; A61P31/18; A61P31/20
Foreign References:
| CN1618795A | 2005-05-25 | |||
| CN1321641A | 2001-11-14 | |||
| CN1149871A | 1997-05-14 |
Other References:
See also references of EP 2161267A4
Attorney, Agent or Firm:
SHANGHAI L & W INTELLECTUAL PROPERTY LAW OFFICE, LLC (Suite 3011698 Yi Shan Road, Shanghai 3, CN)
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