Title:
PROCESSES FOR PRODUCING VANCOMYCIN
Document Type and Number:
WIPO Patent Application WO/1998/026085
Kind Code:
A1
Abstract:
Decoloring processes appropriate for the economical production of vancomycin on an industrial scale whereby a favorable decoloring effect and a high yield can be both established, characterized by bringing vancomycin into contact with adsorbent phenol resins which can be regenerated without resort to any organic solvents. These processes are typified by one comprising passing an acidic vancomycin solution through an adsorbent phenol resin to thereby give the eluate and another one comprising passing a weakly alkaline vancomycin solution through an adsorbent phenol resin and eluting the vancomycin thus adsorbed with an acidified lower alcohol to thereby give the eluate.
Inventors:
NISHIYAMA HIROAKI (JP)
ASADA HAJIME (JP)
ASADA HAJIME (JP)
Application Number:
PCT/JP1997/004460
Publication Date:
June 18, 1998
Filing Date:
December 05, 1997
Export Citation:
Assignee:
NIPPON KAYAKU KK (JP)
NISHIYAMA HIROAKI (JP)
ASADA HAJIME (JP)
NISHIYAMA HIROAKI (JP)
ASADA HAJIME (JP)
International Classes:
C07K9/00; C12P21/04; (IPC1-7): C12P21/04
Foreign References:
| EP0528117A2 | 1993-02-24 | |||
| US4440753A | 1984-04-03 | |||
| JPS57141253A | 1982-09-01 |
Other References:
ENCYCLOPAEDIA CHIMICA 5 (Reduced-Size Edition 30th Printing), KYORITSU SHUPPAN K.K., 1987, page 649, "Decolorizing Resin".
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