Title:
PRODRUGS OF VANCOMYCIN WITH HYDROLYSIS RESISTANT POLYMER LINKERS
Document Type and Number:
WIPO Patent Application WO2004044223
Kind Code:
A3
Abstract:
Vancomycin-polymer conjugates are disclosed. In preferred aspects, polymer residues which are hydrolysis resistant in vitro, are selectively attached to the sugar amino and/or N-methyl amino groups of vancomycin and related compounds. Vancomycin-polymer conjugates made by the methods and methods of treatment using the conjugates are also disclosed.
Inventors:
GREENWALD RICHARD B
ZHAO HONG
ZHAO HONG
Application Number:
PCT/US2003/035741
Publication Date:
July 22, 2004
Filing Date:
November 11, 2003
Export Citation:
Assignee:
ENZON PHARMACEUTICALS INC (US)
International Classes:
A61K38/14; C07K9/00; C08H1/00; C12Q; (IPC1-7): A61K38/14; C07K9/00; C08H1/00
Foreign References:
| JP2000302687A | 2000-10-31 | |||
| US5965119A | 1999-10-12 | |||
| US5965566A | 1999-10-12 |
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