Title:
PRODUCTION METHOD FOR CHEMICALS BY CONTINUOUS FERMENTATION
Document Type and Number:
WIPO Patent Application WO/2012/036003
Kind Code:
A1
Abstract:
A production method for chemicals by continuous fermentation, comprising: filtering a culture medium containing a fermentation feedstock, chemicals, microbes, or cultured cells by a separation membrane; collecting the chemicals from the filtrate; retaining or refluxing the unfiltered remains in the culture medium; and supplying washing liquid from the permeate side of a membrane unit to wash the membrane in a continuous fermentation in which the fermentation feedstock is added to the culture medium, characterized in that the washing liquid has a higher temperature than the culture medium, and is high-temperature water of 150°C or lower, and a microbial concentration in a fermenter is controlled by supplying the washing liquid. By using the production method, the retention of the filtration property for high cell-density cultivation of microbial mixture and the control of the microbial concentration can be simultaneously performed, in the collection of products by the fermentation using the separation membrane.
Inventors:
KOBAYASHI ATSUSHI
CHEON JIHOON
TAKEUCHI NORIHIRO
NISHIDA MAKOTO
TANAKA YUJI
MINEGISHI SHIN-ICHI
CHEON JIHOON
TAKEUCHI NORIHIRO
NISHIDA MAKOTO
TANAKA YUJI
MINEGISHI SHIN-ICHI
Application Number:
PCT/JP2011/070109
Publication Date:
March 22, 2012
Filing Date:
September 05, 2011
Export Citation:
Assignee:
TORAY INDUSTRIES (JP)
KOBAYASHI ATSUSHI
CHEON JIHOON
TAKEUCHI NORIHIRO
NISHIDA MAKOTO
TANAKA YUJI
MINEGISHI SHIN-ICHI
KOBAYASHI ATSUSHI
CHEON JIHOON
TAKEUCHI NORIHIRO
NISHIDA MAKOTO
TANAKA YUJI
MINEGISHI SHIN-ICHI
International Classes:
B01D65/02; C12P1/00; B01D65/06; C12P7/40; C12P7/56
Domestic Patent References:
| WO2007097260A1 | 2007-08-30 |
Foreign References:
| JP2008099667A | 2008-05-01 | |||
| JP2009065966A | 2009-04-02 | |||
| JP2009065970A | 2009-04-02 | |||
| JP2008199948A | 2008-09-04 | |||
| JP2000317273A | 2000-11-21 | |||
| JP2011188791A | 2011-09-29 | |||
| JPH08141375A | 1996-06-04 | |||
| JP2001038177A | 2001-02-13 | |||
| JP2002126470A | 2002-05-08 | |||
| JP2008289959A | 2008-12-04 | |||
| JP3577992B2 | 2004-10-20 | |||
| JP2006314883A | 2006-11-24 |
Other References:
See also references of EP 2617832A4
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Claims: