Title:
PRODUCTION METHOD FOR L-CYCLIC AMINO ACIDS
Document Type and Number:
WIPO Patent Application WO/2020/218624
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing a method for more easily and highly efficiently industrially producing high-purity L-cyclic amino acids from cyclic amino acids that have a double bond at the 1 position. According to the present invention, an L-cyclic amino acid is produced by making a specific enzyme act on a cyclic amino acid that has a double bond at the 1 position, the specific enzyme having catalytic performance that reduces cyclic amino acids that have a double bond at the 1 position to generate L-cyclic amino acids.
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Inventors:
MIZUTANI MASAHARU (JP)
MIYAKE RYOMA (JP)
KAWABATA HIROSHI (JP)
MIYAKE RYOMA (JP)
KAWABATA HIROSHI (JP)
Application Number:
PCT/JP2020/019517
Publication Date:
October 29, 2020
Filing Date:
May 15, 2020
Export Citation:
Assignee:
API CORP (JP)
International Classes:
C12P13/04; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N9/06; C12N15/29; C12N15/53; C12N15/63; C12P41/00
Domestic Patent References:
| WO2015033636A1 | 2015-03-12 | |||
| WO2002101003A2 | 2002-12-19 |
Foreign References:
| EP1033405A2 | 2000-09-06 | |||
| JP4590981B2 | 2010-12-01 | |||
| JPS57183799A | 1982-11-12 |
Other References:
DATABASE UniProtRB 14 May 2014 (2014-05-14), ANONYMOUS: "SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EXC05955.1; LOC21397372 protein SAR DEFICIENT 4 [ Morus notabilis ]", XP009524608, retrieved from Gene Database accession no. W9SGT1
F GARCIA ET AL., TETRAHYDRON ASYMMETRY, vol. 6, 1995, pages 2905 - 2906
TADASHI FUJII ET AL., BIOSCIENCE BIOTECHNOLOGY BIOCHEM, vol. 66, 2002, pages 1981 - 1984
RALPH N COSTILOW ET AL., JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 246, 1971, pages 6655 - 6660
ALTON MEISTER ET AL., JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 229, 1957, pages 789 - 800
CECIL W PAYTON ET AL., JOURNAL OF BACTERIOLOGY, vol. 149, 1982, pages 864 - 871
KARLIN ET AL., PROC. NATL. ACAD. SCI. USA, vol. 90, 1993, pages 5873 - 5877
ALTSCHUL ET AL., NUCLEIC ACIDS RES., vol. 25, 1997, pages 3389 - 3402
NEEDLEMAN ET AL., J. MOL. BIOL., vol. 48, 1970, pages 444 - 453
MYERSMILLER, CABIOS, vol. 4, 1988, pages 11 - 17
PEARSON ET AL., PROC. NATL. ACAD. SCI. USA, vol. 85, 1988, pages 2444 - 2448
"Current Protocols in Molecular Biology", vol. 16, 1999, JOHN WILEY & SONS
"Nucleic Acids Res.", vol. 10, 1982, pages: 6487
METHODS IN ENZYMOL., vol. 100, 1983, pages 448
"Molecular Cloning, PCR A Practical Approach", 1991, IRL PRESS, pages: 200
GENE, vol. 26, 1983, pages 273 - 82
GENE, vol. 39, 1985, pages 281
MOL. GEN. GENET., vol. 196, 1984, pages 175
TRENDSIN BIOTECHNOLOGY, vol. 7, 1989, pages 283 - 287
NATURE, vol. 315, 1985, pages 592 - 594
ENZYME AND MICROBIAL TECHNOLOGY, vol. 31, 2002, pages 77 - 87
HANES CS, BIOCHEMICAL JOURNAL, vol. 26, no. 5, 1932, pages 1406
MURAMATSU ET AL., JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 280, no. 7, 2005, pages 5329
See also references of EP 3960869A4
F GARCIA ET AL., TETRAHYDRON ASYMMETRY, vol. 6, 1995, pages 2905 - 2906
TADASHI FUJII ET AL., BIOSCIENCE BIOTECHNOLOGY BIOCHEM, vol. 66, 2002, pages 1981 - 1984
RALPH N COSTILOW ET AL., JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 246, 1971, pages 6655 - 6660
ALTON MEISTER ET AL., JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 229, 1957, pages 789 - 800
CECIL W PAYTON ET AL., JOURNAL OF BACTERIOLOGY, vol. 149, 1982, pages 864 - 871
KARLIN ET AL., PROC. NATL. ACAD. SCI. USA, vol. 90, 1993, pages 5873 - 5877
ALTSCHUL ET AL., NUCLEIC ACIDS RES., vol. 25, 1997, pages 3389 - 3402
NEEDLEMAN ET AL., J. MOL. BIOL., vol. 48, 1970, pages 444 - 453
MYERSMILLER, CABIOS, vol. 4, 1988, pages 11 - 17
PEARSON ET AL., PROC. NATL. ACAD. SCI. USA, vol. 85, 1988, pages 2444 - 2448
"Current Protocols in Molecular Biology", vol. 16, 1999, JOHN WILEY & SONS
"Nucleic Acids Res.", vol. 10, 1982, pages: 6487
METHODS IN ENZYMOL., vol. 100, 1983, pages 448
"Molecular Cloning, PCR A Practical Approach", 1991, IRL PRESS, pages: 200
GENE, vol. 26, 1983, pages 273 - 82
GENE, vol. 39, 1985, pages 281
MOL. GEN. GENET., vol. 196, 1984, pages 175
TRENDSIN BIOTECHNOLOGY, vol. 7, 1989, pages 283 - 287
NATURE, vol. 315, 1985, pages 592 - 594
ENZYME AND MICROBIAL TECHNOLOGY, vol. 31, 2002, pages 77 - 87
HANES CS, BIOCHEMICAL JOURNAL, vol. 26, no. 5, 1932, pages 1406
MURAMATSU ET AL., JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 280, no. 7, 2005, pages 5329
See also references of EP 3960869A4
Attorney, Agent or Firm:
IP FIRM SHUWA (JP)
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