AROMATICUM (CLOVE), LAVENDULA (LAVENDER), THYMUS (THYME) , CITRUS (ORANGE, LEMON)

Technical Field

The invention relates to products that are effective against pathogenic microorganisms (bacteria, fungi and viruses) and are also used as skin moisturisers and surface cleaners.

State of the Art

In general, moisturizing hand sanitizer refers to antimicrobial hand sanitizers that include alcohols that kill bacteria while also moisturizing the wearer's skin. More particularly, alcohol-based hand sanitizers have a high internal phase emulsion, which ensures the stable integration of moisturizers or skin protectants into the disinfection, such as emollients and/or silicones. It is, however, for a moisturizing hand sanitizer including water, alcohol, and a high internal phase emulsion. An emulsifier and a skin protectant from the group consisting of an emollient, silicone, and combinations thereof are present in the high internal phase emulsion. The high internal phase emulsion contains an aqueous phase of about 30% (by weight of the emulsion) or less. The intended use of alcohol in moisturising hand sanitiser is to provide the disinfectant with microbiocidal properties against most bacteria and fungi, while alcohol has the ability to suitably kill gram-positive and/or gram-negative bacteria, fungi, mould, various viruses, protozoa, parasites, and other microbes. It is known that the potent activity of alcohol against a microorganism is due to the denaturation of proteins and enzymes and cellular dehydration. In general, the more concentrated the alcohol in the disinfectant, the stronger the antimicrobial effect is expected. However, it needs additional compounds (such as Quaternary ammonium compounds, phenolic compounds and iodophors) as increasing the alcohol concentration has the detrimental effect of increasing the level of skin irritation for disinfectant users. Studies have shown that the effectiveness of the same disinfectant applied in different amounts such as 1 ml and 2,4 ml (FDA value) is insufficient for hands, since 1 .1 ml cannot cover the entire hand surface. Suitably, the hand sanitiser of the present disclosure comprises about 20% (by weight of disinfectant) to about 95% (by weight of disinfectant) and more typically about 60% (by weight of disinfectant) to about 95% (by weight of disinfectant) alcohol. In one particular embodiment, the hand sanitiser comprises isopropyl alcohol in an amount of about 20% (by weight of disinfectant) to about 95% (by weight of disinfectant) and more typically about 50% (by weight of disinfectant) to about 91.3% (by weight of disinfectant). Suitable disinfectants include, for example, quaternium compounds, biguanidines, halogenated compounds and combinations thereof. In preferred embodiments, disinfectants are FDA-approved or approved for use in the European Union. Examples of appropriate FDA-approved disinfectants are in the Interim Final Monograph for OTC Topical Antimicrobial Products (Federal Register, Jan. 6, 1978, 43 FR 1210: 1211 -49) and in the Provisional Final Monograph for Healthcare Antiseptic Drug Products (Federal Register, 17 Jun 1994, 59 FR 31402, 31402-52). As noted above, the alcohol in hand sanitiser can cause dryness, irritation and cracking on the user's skin. To help heal and protect the user's skin, disinfectants of the present disclosure also include one or more moisturisers or another skin protectant such as an emollient and/or a silicone. To avoid the instability that occurs when a moisturiser is added to an alcohol-based disinfectant, the disinfectants of the present disclosure are advantageously formulated using a high internal phase emulsion ("HIPE") comprising a softener and/or a silicone. When a moisturiser or skin protectant (eg, emollient and/or silicone) is added to the disinfectant as part of a HIPE, the moisturiser or skin protectant is not separated from the disinfectant. As a result, the disinfectant is largely stable over long periods of time.

The HIPE preferably has an average droplet size of about 5 microns or less. It is believed that it is the droplet size of the HIPE (and thus softeners and/or silicones) that lasts long in the disinfectant without deteriorating.

Suitable esters may include, but are not limited to, cetyl palmitate, stearyl palmitate, cetyl stearate, isopropyl laurate, isopropyl myristate, isopropyl palmitate, and combinations thereof. Fatty alcohols can generally include octyldodecanol, lauryl, myristyl, cetyl, stearyl, behenyl alcohol, and combinations thereof. Ethers such as eucalyptol, ceteraryl glucoside, dimethyl isosorbic polyglyceryl-3 cetyl ether, polyglyceryl-3 decyltetradecanol, propylene glycol myristyl ether and combinations thereof can also be used as softeners.

The difference of the patent presented is as follows: In the related patent, the damage to the skin caused using chemicals has been revealed, and all the compounds considered as moisturisers are generally obtained by chemical means. Said patent will use the extracts to be obtained without the use of chemicals in the production of disinfectants, and their positive effect on both nature and human health will be determined. In order to increase the antimicrobial activity, instead of increasing the alcohol concentration and/or increasing the synthetic substance ratio, the efficiency of extracts obtained from plants will be used, and the ferulic acid obtained from wheat bran will also have an effect on skin protection.

Description of the Invention

The content of our product is as follows.

Syzygium aromaticum (clove) 30mg extract, +70ml (70%EtOH) + 30ml dF +5mg Ferulic acid

Lavandula (lavender) 33mg extract, + 70ml (70%EtOH) + 30ml dH2O+5mg Ferulic acid

Thymus (thyme) 25mg extract, + 70ml (70%EtOH) + 30ml dH2O+5mg Ferulic acid

Citrus (orange, lemon) 29mg extract + 70ml (70%EtOH) + 30ml dH2O+5mg Ferulic acid. Our products introduced to market in spray capped bottles.

Application of the Invention to the Industry

Our product can be used in every public area (hospitals, health centres, university laboratories, restaurants, veterinary clinics...) indoor and outdoor areas.