Title:
PROGNOSIS METHOD FOR BLOOD DISORDERS
Document Type and Number:
WIPO Patent Application WO/2021/239665
Kind Code:
A1
Abstract:
The invention relates to a method for determining the risk of developing a blood disorder, comprising the following steps: - exposing a biological sample to radiation to obtain a spectrum characteristic of the sample, the spectrum being processed in order to obtain a spectral signature; - comparing the spectral signature obtained in the previous step with one or more reference spectral signatures; and - concluding * if the spectral signature of the individual is significantly different from control spectral signatures, that the individual is likely to develop a blood disorder, and * if not, that the individual is not likely to develop a blood disorder. The invention relates to a method for determining the risk of developing a blood disorder, comprising the following steps: - exposing a biological sample to radiation to obtain a spectrum characteristic of the sample, the spectrum being processed in order to obtain a spectral signature; - comparing the spectral signature obtained in the previous step with one or more reference spectral signatures; and - concluding * if the spectral signature of the individual is significantly different from control spectral signatures, that the individual is likely to develop a blood disorder, and * if not, that the individual is not likely to develop a blood disorder.
Inventors:
HERAULT OLIVIER (FR)
SIRE OLIVIER (FR)
SIRE OLIVIER (FR)
Application Number:
PCT/EP2021/063762
Publication Date:
December 02, 2021
Filing Date:
May 24, 2021
Export Citation:
Assignee:
CENTRE NAT RECH SCIENT (FR)
CENTRE HOSPITALIER REGIONAL UNIV DE TOURS (FR)
UNIV TOURS (FR)
CENTRE HOSPITALIER REGIONAL UNIV DE TOURS (FR)
UNIV TOURS (FR)
International Classes:
G01N21/3577; G01N21/35; G01N21/552
Domestic Patent References:
| WO2011121588A1 | 2011-10-06 |
Foreign References:
| US20130137134A1 | 2013-05-30 |
Other References:
LE CORVEC MAËNA ET AL: "Mid-infrared spectroscopy of serum, a promising non-invasive method to assess prognosis in patients with ascites and cirrhosis", PLOS ONE, vol. 12, no. 10, 2017, pages 1 - 15, XP055772274, DOI: 10.1371/journal.pone.0185997
SHENG DAPING ET AL: "Distinction of leukemia patients and healthy persons' serum using FTIR spectroscopy", SPECTROCHIMICA ACTA PART A: MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2013, pages 228 - 232, XP055772773, Retrieved from the Internet [retrieved on 20210205]
BABRAH JASPREET ET AL: "FT-infrared spectroscopic studies of lymphoma, lymphoid, and myeloid leukemia cell lines", SPIE PROCEEDINGS, vol. 6628, 2007, US, pages 1 - 8, XP055772606, ISBN: 978-1-5106-3673-6, DOI: 10.1117/12.728220
SHENG DAPING ET AL: "Distinction of leukemia patients and healthy persons' serum using FTIR spectroscopy", SPECTROCHIMICA ACTA PART A: MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2013, pages 228 - 232, XP055772773, Retrieved from the Internet
BABRAH JASPREET ET AL: "FT-infrared spectroscopic studies of lymphoma, lymphoid, and myeloid leukemia cell lines", SPIE PROCEEDINGS, vol. 6628, 2007, US, pages 1 - 8, XP055772606, ISBN: 978-1-5106-3673-6, DOI: 10.1117/12.728220
Attorney, Agent or Firm:
MONNI, Richard (FR)
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