Title:
PROGNOSTIC BIOMARKER FOR CANCER
Document Type and Number:
WIPO Patent Application WO/2022/154037
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide a biomarker for predicting the prognosis of a cancer patient and an antibody for detecting the biomarker. Provided is a biomarker for predicting the prognosis of a cancer patient, said biomarker comprising liver receptor homolog 1 in which the serine residue at the position 510 in the amino acid sequence represented by SEQ ID NO:1 is phosphorylated (pSer510-LRH1).
Inventors:
CHIBA HIDEKI (JP)
KOBAYASHI MAKOTO (JP)
SUGIMOTO KOTARO (JP)
KOBAYASHI MAKOTO (JP)
SUGIMOTO KOTARO (JP)
Application Number:
PCT/JP2022/000848
Publication Date:
July 21, 2022
Filing Date:
January 13, 2022
Export Citation:
Assignee:
UNIV FUKUSHIMA MEDICAL (JP)
International Classes:
C07K16/28; G01N33/15; G01N33/50; G01N33/574
Foreign References:
| JP2013245960A | 2013-12-09 | |||
| JP2016535270A | 2016-11-10 | |||
| JP2012515334A | 2012-07-05 |
Other References:
SUN WENZHOU, SHI QINGTAO, LI JIAXIN, LI JINMENG, YU LIBO: "LRH1 Promotes Tumor Cell Proliferation and Migration and Is Correlated With Poor Prognosis in Ovarian Cancer", FRONTIERS IN ONCOLOGY, vol. 10, 20 October 2020 (2020-10-20), pages 1 - 11, XP055951987, DOI: 10.3389/fonc.2020.583566
NADOLNY CHRISTINA, DONG XIAOQUN: "Liver receptor homolog-1 (LRH-1): a potential therapeutic target for cancer", CANCER BIOLOGY & THERAPY, vol. 16, no. 7, 1 January 2015 (2015-01-01), US , pages 997 - 1004, XP055951990, ISSN: 1538-4047, DOI: 10.1080/15384047.2015.1045693
NADOLNY CHRISTINA, DONG XIAOQUN: "Liver receptor homolog-1 (LRH-1): a potential therapeutic target for cancer", CANCER BIOLOGY & THERAPY, vol. 16, no. 7, 1 January 2015 (2015-01-01), US , pages 997 - 1004, XP055951990, ISSN: 1538-4047, DOI: 10.1080/15384047.2015.1045693
Attorney, Agent or Firm:
HIRAKI & ASSOCIATES (JP)
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