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Title:
PROPHYLACTIC OR THERAPEUTIC AGENT FOR ALOPECIA
Document Type and Number:
WIPO Patent Application WO/2008/075735
Kind Code:
A1
Abstract:
Disclosed is a novel therapeutic agent which is useful for the prevention or treatment of alopecia. Specifically disclosed is a prophylactic or therapeutic agent for alopecia, which comprises 1-[2-((2S)-2-[5-[(3,4-dimethoxyphenoxy)methyl]-1,2,4- oxadiazol-3-yl]pyrrolidin-1-yl)-1,1-difluoro-2-oxoethyl]- 3,3,5,5-tetramethylcyclohexanol as an active ingredient.

Inventors:
NAKAO AKIKO (JP)
UEMATSU NATSUKO (JP)
TAKAHASHI AKIKO (JP)
YOKOTA SHIN-ICHI (JP)
Application Number:
PCT/JP2007/074496
Publication Date:
June 26, 2008
Filing Date:
December 20, 2007
Export Citation:
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Assignee:
TAISHO PHARMACEUTICAL CO LTD (JP)
NAKAO AKIKO (JP)
UEMATSU NATSUKO (JP)
TAKAHASHI AKIKO (JP)
YOKOTA SHIN-ICHI (JP)
International Classes:
A61K31/4245; A61K8/49; A61P17/14; A61Q7/00; C07D413/04
Domestic Patent References:
WO1996040633A11996-12-19
WO1992019593A11992-11-12
WO2000027811A12000-05-18
WO1999062511A11999-12-09
WO1999045006A11999-09-10
WO2005000231A22005-01-06
WO2001042245A12001-06-14
WO1998055090A11998-12-10
Foreign References:
JP2004123557A2004-04-22
JP2002510301A2002-04-02
JP2925285B21999-07-28
JP2004123556A2004-04-22
JP2004123557A2004-04-22
Other References:
YAMAMOTO ET AL., J. INVEST. DERMATOL., vol. 102, 1994, pages 160 - 164
FREYSCHMIDT-PAUL ET AL., EUR. J. DERMATOL., vol. 11, 2001, pages 405 - 409
MCELWEE ET AL., BR. J. DERMATOL., vol. 137, 1997, pages 491 - 497
JIANG ET AL., J. INVEST. DERMATOL., vol. 104, 1995, pages 523 - 525
MAURER ET AL., AM. J. PATHOL., vol. 150, 1997, pages 1433 - 1441
See also references of EP 2100588A4
Attorney, Agent or Firm:
Patent Corporate body of Ono & Co. (1-13-1 Kandaizumi-cho, Chiyoda-ku Tokyo 24, JP)
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