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Title:
PROPHYLACTIC OR THERAPEUTIC AGENT FOR DYSURIA
Document Type and Number:
WIPO Patent Application WO/2013/084532
Kind Code:
A1
Abstract:
The present invention provides a prophylactic or therapeutic agent for dysuria which comprises, as the active ingredient, prosultiamine, fursultiamine, a metabolite thereof, or a pharmaceutically acceptable salt thereof.

Inventors:
NAKAMURA TATSUFUMI (JP)
MATSUO TOMOHIRO (JP)
SAKAI HIDEKI (JP)
Application Number:
PCT/JP2012/067984
Publication Date:
June 13, 2013
Filing Date:
July 13, 2012
Export Citation:
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Assignee:
UNIV NAGASAKI (JP)
NAKAMURA TATSUFUMI (JP)
MATSUO TOMOHIRO (JP)
SAKAI HIDEKI (JP)
International Classes:
A61K31/505; A61K31/51; A61P3/10; A61P9/00; A61P13/02; A61P13/08; A61P13/10; A61P25/00; A61P25/16; A61P35/00
Foreign References:
JP2007277223A2007-10-25
Other References:
KOICHIRO NOMATA ET AL.: "Bladder Involvement in HTLV-I Associated Myelopathy", THE JAPANESE JOURNAL OF UROLOGY, vol. 82, no. 7, July 1991 (1991-07-01), pages 1161 - 1164
TAKASHIGE NAMIMA ET AL.: "TWO CASES OF NEUROGENIC BLADDER DUE TO HTLV-1 ASSOCIATED MYELOPATHY (HAM)", THE JAPANESE JOURNAL OF UROLOGY, vol. 81, no. 3, March 1990 (1990-03-01), pages 475 - 478
RYUJI TAKAGI ET AL.: "Shinkeiinsei Boko no Yakubutsu Ryoho", KUSURI NO CHISHIKI, vol. 37, no. 2, February 1986 (1986-02-01), pages 10 - 11
KEN'ICHI IMABAYASHI: "Biochemical analysis of the effect of active vitamin Bl, TTFD, on the neurogenic bladder", HINYO KIYO, vol. 12, no. 9, 1966, pages 977 - 984
SHISHITO,S. ET AL.: "Experimental review on the neurogenic bladder--its pathological physiology and biochemistry, and the effects of relating therapeutic agents", TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE, vol. 82, 1964, pages 327 - 48
KANEYUKI FURUTA ET AL.: "Clinical Studies of ALINAMIN-F (TTFD) Effect on the Urination Disturbance induced by the Radical Operation of Uterus Carcinoma II. On Effect of ALINAMIN-F (TTFD) and ADETPHOS-KOWA No.3 (ATP:2Na) directly injected into Urine Bladder", ADVANCES IN OBSTETRICS AND GYNAECOLOGY, vol. 16, no. 5, 1964, pages 263 - 264
"Keiko Prosultiamine ni yoru HTLV-I Kanren Sekizuisho (HAM) ni Taisuru Shinki Chiryoho Kaihatsu ni Muketa Rinsho Shiken", 15 July 2011 (2011-07-15), Retrieved from the Internet [retrieved on 20120816]
"Clinical trial aimed at new therapeutic strategy for HAM by prosultiamine treatment with oral administration", 15 July 2011 (2011-07-15), Retrieved from the Internet [retrieved on 20120816]
Attorney, Agent or Firm:
TAKASHIMA, HAJIME (JP)
Takashima 1 (JP)
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Claims: