Title:
PROPHYLACTIC AND THERAPEUTIC AGENT FOR SEPSIS
Document Type and Number:
WIPO Patent Application WO/2010/038656
Kind Code:
A1
Abstract:
Disclosed is a prophylactic and therapeutic agent for sepsis, which comprises at least one component selected from the group consisting of a cyclic tetrasaccharide of which a constituent saccharide is glucose, a cyclic pentasaccharide of which a constituent saccharide is glucose and derivatives of the cyclic tetrasaccharide and the cyclic pentasaccharide as an active ingredient.
The prophylactic and therapeutic agent for sepsis can prevent and treat sepsis without inducing any adverse side effect such as hemolysis.
Inventors:
NISHIMURA MASUHIRO (JP)
SHIBUTANI TADAO (JP)
KIRYU KIMIO (JP)
FUKUNAGA TETSUYA (JP)
DOI MASAKO (JP)
TAMURA NOZOMI (JP)
WATANABE HIKARU (JP)
YAMAMOTO ROHKO (JP)
NISHIMOTO TOMOYUKI (JP)
SHIBUTANI TADAO (JP)
KIRYU KIMIO (JP)
FUKUNAGA TETSUYA (JP)
DOI MASAKO (JP)
TAMURA NOZOMI (JP)
WATANABE HIKARU (JP)
YAMAMOTO ROHKO (JP)
NISHIMOTO TOMOYUKI (JP)
Application Number:
PCT/JP2009/066593
Publication Date:
April 08, 2010
Filing Date:
September 25, 2009
Export Citation:
Assignee:
HAYASHIBARA BIOCHEM LAB (JP)
OTSUKA PHARMA CO LTD (JP)
NISHIMURA MASUHIRO (JP)
SHIBUTANI TADAO (JP)
KIRYU KIMIO (JP)
FUKUNAGA TETSUYA (JP)
DOI MASAKO (JP)
TAMURA NOZOMI (JP)
WATANABE HIKARU (JP)
YAMAMOTO ROHKO (JP)
NISHIMOTO TOMOYUKI (JP)
OTSUKA PHARMA CO LTD (JP)
NISHIMURA MASUHIRO (JP)
SHIBUTANI TADAO (JP)
KIRYU KIMIO (JP)
FUKUNAGA TETSUYA (JP)
DOI MASAKO (JP)
TAMURA NOZOMI (JP)
WATANABE HIKARU (JP)
YAMAMOTO ROHKO (JP)
NISHIMOTO TOMOYUKI (JP)
International Classes:
A61K31/702; A61P31/04; C07H3/06
Domestic Patent References:
| WO2006035725A1 | 2006-04-06 | |||
| WO2006115067A1 | 2006-11-02 | |||
| WO2007013122A1 | 2007-02-01 |
Foreign References:
| JP2005095148A | 2005-04-14 | |||
| JP2008056631A | 2008-03-13 | |||
| JPH03133931A | 1991-06-07 |
Other References:
GREGORY L. C. ET AL.: "Enzymically Produced Cyclic a-1,3-Linked and a-1,6-Linked Oligosaccharides of d-Glucose.", EUROPEAN JOURNAL OF BIOCHEMISTRY, vol. 226, no. 2, 1994, pages 641 - 648
HIDETOSHI ARIMA: "Cyclodextrin no Saranaru Kanosei o Motomete", JOURNAL OF PHARMACEUTICAL SCIENCE AND TECHNOLOGY, vol. 63, no. 3, 2003, JAPAN, pages 125 - 128
KEIICHI MOTOYAMA: "Endotoxin Shock Yokuseizai toshite no Dimethyl Acetyl-ยง-Cyclodextrin no Yuko Riyo", JOURNAL OF PHARMACEUTICAL SCIENCE AND TECHNOLOGY, vol. 68, no. 3, May 2008 (2008-05-01), JAPAN, pages 196 - 201
HIROSHI NISHIMOTO ET AL.: "Cyclodextrin Yudotai ni yoru Macrophage kara no NO Sansei no Yokusei", ABSTRACTS OF ANNUAL MEETING OF PHARMACEUTICAL SOCIETY OF JAPAN, vol. 120, no. 4, 2000, pages 21
HIDETOSHI ARIMA: "Cyclodextrin no Saranaru Kanosei o Motomete", JOURNAL OF PHARMACEUTICAL SCIENCE AND TECHNOLOGY, vol. 63, no. 3, 2003, JAPAN, pages 125 - 128
KEIICHI MOTOYAMA: "Endotoxin Shock Yokuseizai toshite no Dimethyl Acetyl-ยง-Cyclodextrin no Yuko Riyo", JOURNAL OF PHARMACEUTICAL SCIENCE AND TECHNOLOGY, vol. 68, no. 3, May 2008 (2008-05-01), JAPAN, pages 196 - 201
HIROSHI NISHIMOTO ET AL.: "Cyclodextrin Yudotai ni yoru Macrophage kara no NO Sansei no Yokusei", ABSTRACTS OF ANNUAL MEETING OF PHARMACEUTICAL SOCIETY OF JAPAN, vol. 120, no. 4, 2000, pages 21
Attorney, Agent or Firm:
SAEGUSA & PARTNERS (JP)
Patent business corporation 3 Edakuni [Hajime] patent firm (JP)
Patent business corporation 3 Edakuni [Hajime] patent firm (JP)
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