Title:
PROSTATE STEM CELL
Document Type and Number:
WIPO Patent Application WO2005089043
Kind Code:
A3
Abstract:
We describe a method for the isolation of prostate stem cells, typically prostate cancer stem cells which express CD 133 antigen; stem cells and cancer stem cells isolated by the method and their use.
Inventors:
MAITLAND NORMAN (GB)
COLLINS ANNE (GB)
COLLINS ANNE (GB)
Application Number:
PCT/GB2005/001142
Publication Date:
June 08, 2006
Filing Date:
March 18, 2005
Export Citation:
Assignee:
PROCURE THERAPEUTICS LTD (GB)
MAITLAND NORMAN (GB)
COLLINS ANNE (GB)
MAITLAND NORMAN (GB)
COLLINS ANNE (GB)
International Classes:
A61K39/395; C07K16/30; C12N5/095; G01N33/50; G01N33/574; A61K39/00
Other References:
RICHARDSON GAVIN D ET AL: "CD133, a novel marker for human prostatic epithelial stem cells", JOURNAL OF CELL SCIENCE, vol. 117, no. 16, 15 July 2004 (2004-07-15), pages 3539 - 3545, XP002354680, ISSN: 0021-9533
COLLINS ANNE T ET AL: "Identification and isolation of human prostate epithelial stem cells based on alpha2beta1-integrin expression", JOURNAL OF CELL SCIENCE, vol. 114, no. 21, November 2001 (2001-11-01), pages 3865 - 3872, XP002354681, ISSN: 0021-9533
BHATT RUPESH I ET AL: "Novel method for the isolation and characterisation of the putative prostatic stem cell.", CYTOMETRY, vol. 54A, no. 2, August 2003 (2003-08-01), pages 89 - 99, XP002354682, ISSN: 0196-4763
YIN A H ET AL: "AC133, a novel marker for human hematopoietic stem and progenitor cells", BLOOD, W.B. SAUNDERS, PHILADELPHIA, VA, US, vol. 90, no. 12, 15 December 1997 (1997-12-15), pages 5002 - 5012, XP002264586, ISSN: 0006-4971
COLLINS ANNE T ET AL: "Identification and isolation of human prostate epithelial stem cells based on alpha2beta1-integrin expression", JOURNAL OF CELL SCIENCE, vol. 114, no. 21, November 2001 (2001-11-01), pages 3865 - 3872, XP002354681, ISSN: 0021-9533
BHATT RUPESH I ET AL: "Novel method for the isolation and characterisation of the putative prostatic stem cell.", CYTOMETRY, vol. 54A, no. 2, August 2003 (2003-08-01), pages 89 - 99, XP002354682, ISSN: 0196-4763
YIN A H ET AL: "AC133, a novel marker for human hematopoietic stem and progenitor cells", BLOOD, W.B. SAUNDERS, PHILADELPHIA, VA, US, vol. 90, no. 12, 15 December 1997 (1997-12-15), pages 5002 - 5012, XP002264586, ISSN: 0006-4971
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