Title:
PROTACS OF MALT1
Document Type and Number:
WIPO Patent Application WO/2023/164175
Kind Code:
A3
Abstract:
The present invention is directed to compounds of Formula (I), characterized as PROTACs of MALT1. The PROTACs described herein can be useful in the treatment of diseases or disorders associated with MALT1, such as lymphoma. In particular, the invention is concerned with compounds and pharmaceutical compositions capable of degrading MALT1, methods of treating diseases or disorders associated with MALT1, and methods of synthesizing these compounds. (I)
Inventors:
ABAGYAN RUBEN (US)
PARCHINSKY VLADISLAV (RU)
KHVAT ALEXANDER (US)
IVACHTCHENKO ALEXANDRE (US)
SAVCHUK NIKOLAY (US)
PARCHINSKY VLADISLAV (RU)
KHVAT ALEXANDER (US)
IVACHTCHENKO ALEXANDRE (US)
SAVCHUK NIKOLAY (US)
Application Number:
PCT/US2023/013883
Publication Date:
September 28, 2023
Filing Date:
February 24, 2023
Export Citation:
Assignee:
TEGID THERAPEUTICS INC (US)
International Classes:
A61K31/519; A61K31/4035; A61K31/44; A61K31/495; C07D209/48; C07D213/04; C07D403/14
Domestic Patent References:
| WO2021162493A1 | 2021-08-19 | |||
| WO2020211822A1 | 2020-10-22 |
Foreign References:
| US20190263785A1 | 2019-08-29 | |||
| US20180186785A1 | 2018-07-05 |
Attorney, Agent or Firm:
PAPPALARDO, Paul, A. et al. (US)
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