Title:
PROTECTIVE AGENT FOR NEUROCYTE COMPRISING AMIDINO DERIVATIVE AS ACTIVE INGREDIENT
Document Type and Number:
WIPO Patent Application WO/2006/123675
Kind Code:
A1
Abstract:
Disclosed is a protective agent for a neurocyte. The protective agent comprises a compound represented by the general formula [I] or a salt thereof as an active ingredient. In the general formula [I], R1, R2 and R3 independently represent a hydrogen atom or an alkyl group, or R1 and R3 may together form a ring having one or more double bonds therein.
Inventors:
OOHASHI KOUJI (JP)
DOI REINA (JP)
KAGEYAMA MASAAKI (JP)
DOI REINA (JP)
KAGEYAMA MASAAKI (JP)
Application Number:
PCT/JP2006/309796
Publication Date:
November 23, 2006
Filing Date:
May 17, 2006
Export Citation:
Assignee:
SANTEN PHARMACEUTICAL CO LTD (JP)
OOHASHI KOUJI (JP)
DOI REINA (JP)
KAGEYAMA MASAAKI (JP)
OOHASHI KOUJI (JP)
DOI REINA (JP)
KAGEYAMA MASAAKI (JP)
International Classes:
A61K31/245; A61K31/4168; A61P21/04; A61P25/00; A61P25/02; A61P25/14; A61P25/16; A61P25/28; A61P27/02; A61P27/06; C07D233/50
Domestic Patent References:
| WO2004089918A1 | 2004-10-21 |
Foreign References:
| JP2004536138A | 2004-12-02 | |||
| JP2004516269A | 2004-06-03 | |||
| JP2003246730A | 2003-09-02 |
Other References:
MURKIN J.M.: "Anesthesia, the brain, and cardiopulmonary bypass", THE ANNALS OF THORACIC SURGERY, vol. 56, no. 6, December 1993 (1993-12-01), pages 1461 - 1463, XP003006959
MAEBA T. ET AL: "Jinfuzen Kanja no Ketsueki Joka Ryoho no Sentaku III Nichijo Sogu suru Byotai to Ketsueki Joka Ryoho no Sentaku (7) Kankakuki Shikkan", THE JAPANESE JOURNAL OF CLINICAL DIALYSIS, vol. 16, no. 1, 2000, pages 67 - 72, XP003006960
YANAMOTO H. ET AL.: "Therapeutic trial of cerebral vasospam with the serine protease inhibitor, FUT-175, administered in the acute stage after subarachnoid hemorrhage", NEUROSURGERY, vol. 30, no. 3, 1992, pages 358 - 363, XP003006961
See also references of EP 1884237A4
MAEBA T. ET AL: "Jinfuzen Kanja no Ketsueki Joka Ryoho no Sentaku III Nichijo Sogu suru Byotai to Ketsueki Joka Ryoho no Sentaku (7) Kankakuki Shikkan", THE JAPANESE JOURNAL OF CLINICAL DIALYSIS, vol. 16, no. 1, 2000, pages 67 - 72, XP003006960
YANAMOTO H. ET AL.: "Therapeutic trial of cerebral vasospam with the serine protease inhibitor, FUT-175, administered in the acute stage after subarachnoid hemorrhage", NEUROSURGERY, vol. 30, no. 3, 1992, pages 358 - 363, XP003006961
See also references of EP 1884237A4
Attorney, Agent or Firm:
Hibi, Norihiko c/o KISHIMOTO & CO. (3rd Floor Inaba Building, 13-18,
Nishishinsaibashi 1-chome, Chuo-k, Osaka-shi Osaka 86, JP)
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