PROTEIN DEGRADATION COMPOUNDS AND METHODS OF USE

Title:

PROTEIN DEGRADATION COMPOUNDS AND METHODS OF USE

Document Type and Number:

WIPO Patent Application WO/2024/002289

Kind Code:

A1

Abstract:

This disclosure relates to bivalent compounds (e.g., bi-functional small molecule compounds), compositions comprising one or more of the bivalent compounds, and to methods of use the bivalent compounds for the degrading target proteins associated with a disease or condition.

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Inventors:

LIN CHU-CHIANG (CN)
CHEN HUNG-CHUAN (CN)
CHENG PEI-CHIN (CN)
CHOU CHIH-CHANG (CN)

Application Number:

PCT/CN2023/104153

Publication Date:

January 04, 2024

Filing Date:

June 29, 2023

Export Citation:

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Assignee:

ANHORN MEDICINES CO LTD (CN)
LIN CHU CHIANG (CN)
CHEN HUNG CHUAN (CN)
CHENG PEI CHIN (CN)
CHOU CHIH CHANG (CN)

International Classes:

C07D487/10; A61K31/404; A61K31/454; A61K31/4545; A61K31/496; A61P15/00; C07D403/14

Domestic Patent References:

WO2021143816A1	2021-07-22
WO2021129653A1	2021-07-01
WO2018071606A1	2018-04-19
WO2018144649A1	2018-08-09
WO2022011205A1	2022-01-13

Foreign References:

CN114163444A

2022-03-11

Attorney, Agent or Firm:

AFD CHINA INTELLECTUAL PROPERTY LAW OFFICE (CN)

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