Title:
PROTEIN HAVING α1,2-FUCOSYLTRANSFERASE ACTIVITY AND METHOD FOR PRODUCING LACTO-N-FUCOPENTAOSE I (LNFPI)
Document Type and Number:
WIPO Patent Application WO/2023/182528
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide: a protein that has an α1,2-fucosyltransferase activity and that has excellent LNFPI productivity; and a method for producing LNFPI. The present invention pertains to: a protein that has an activity of transferring fucosyl groups to lacto-N-tetraose (LNT) and that has an amino acid sequence represented by SEQ ID NO. 2, 4, 6, 8, 10, 14, 18, or 26; or a mutant protein or a homologous protein thereof.
Inventors:
KAMAI SAYAKA (JP)
SUGITA TOMOTOSHI (JP)
YAMAZAKI FUHITO (JP)
NAKAMURA KAZUKI (JP)
SUGITA TOMOTOSHI (JP)
YAMAZAKI FUHITO (JP)
NAKAMURA KAZUKI (JP)
Application Number:
PCT/JP2023/012042
Publication Date:
September 28, 2023
Filing Date:
March 24, 2023
Export Citation:
Assignee:
KIRIN HOLDINGS KK (JP)
International Classes:
C12N15/54; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N9/10; C12P19/04
Domestic Patent References:
| WO2022040411A2 | 2022-02-24 |
Foreign References:
| JP2015529453A | 2015-10-08 |
Other References:
DATABASE UNIPROTKB ANONYMOUS : "A0A097EN33 · A0A097EN33_9GAMM", XP093095467, retrieved from UNIPROT
DATABASE UNIPROTKB ANONYMOUS : "A0A7R6P9T7 · A0A7R6P9T7_9GAMM", XP093095468, retrieved from UNIPROT
DATABASE UNIPROTKB ANONYMOUS : "A0A7R6P9T7 · A0A7R6P9T7_9GAMM", XP093095468, retrieved from UNIPROT
Attorney, Agent or Firm:
Eikoh, P.C. (JP)
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