PROTEIN SKELETAL MODULE WHICH INCREASES THE BINDING AFFINITY AND BINDING SPECIFICITY OF ACTIVE POLYPEPTIDES

WIPO Patent Application WO/2012/144799

A2

The present invention relates to a novel protein skeletal module which increases the binding affinity or binding specificity of active polypeptides. More particularly, the present invention relates to a protein skeletal module comprising polypeptides consisting of the 1st to 19th amino acids of the amino acid sequence expressed in sequence number 1; polypeptides comprising active polypeptides; and polypeptides consisting of the 29th to 86th amino acids of the amino acid sequence expressed in sequence number 1. The present invention also relates to a method for preparing the protein skeletal module. The protein skeletal module of the present invention increases the binding affinity or binding specificity of active polypeptides embedded therein, and therefore is effective in diagnosing and treating diseases.

WO/2001/030854	ANTIBODY TO HUMAN GASTROINTESTINAL EPITHELIAL TUMOR ANTIGEN RELATED TO ALPHA 6 BETA 4 INTEGRIN
WO/1999/018202	HUMAN PROTEINS HAVING TRANSMEMBRANE DOMAINS AND cDNAs ENCODING THESE PROTEINS
WO/1999/036539	NUCLEIC ACIDS ENCODING A FUNCTIONAL HUMAN PURINORECEPTOR P2X¿3? AND METHODS OF PRODUCTION AND USE THEREOF

CHA KIWEON (KR)
SO IN-SEOP (KR)
KIM SOYOUN (KR)
LEE BYUNG-HEON (KR)
KIM IN SAN (KR)

PCT/KR2012/002958

October 26, 2012

April 18, 2012

Click for automatic bibliography generation  

KYUNGPOOK NAT UNIV IND ACAD (KR)
CHA KIWEON (KR)
SO IN-SEOP (KR)
KIM SOYOUN (KR)
LEE BYUNG-HEON (KR)
KIM IN SAN (KR)

C07K14/705; C12N15/12; G01N33/68

See references of EP 2700649A4

LEE, Hee Sook et al. (9th Fl. JS Building, Teheran-ro 33 gil 11,Yeoksam-dong, Gangnam-gu, Seoul 135-915, KR)

View/Download PDF      PDF Help

Previous Patent: POLYMER AND PHOTOSENSITIVE RESIN COMPOSITION CONTAINING SAME

Next Patent: LED DRIVING DEVICE AND LED DRIVING METHOD USING SAME