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Title:
PURIFICATION PROCESS
Document Type and Number:
WIPO Patent Application WO/2024/023265
Kind Code:
A3
Abstract:
It is provided a purification processe for removing impurities, such as GroEL, from samples of outer membrane vesicles (OMVs). For example, the process is applied to OMVs derived from Bordetella or from Neisseria, for example Neisseria gonorrhoeae. Also provided are OMVs purified by the processes described herein and immunogenic compositions, such as vaccines, comprising the same.

Inventors:
VANDERCAMMEN ANNE RENÉE J (BE)
NARDI DEI DA FILICAIA DOTTI VINCENZO (BE)
CHAHIM WAEL (BE)
Application Number:
PCT/EP2023/070922
Publication Date:
March 07, 2024
Filing Date:
July 27, 2023
Export Citation:
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Assignee:
GLAXOSMITHKLINE BIOLOGICALS SA (BE)
International Classes:
B01D15/12; A61K35/12; A61K39/02; A61K39/095; B01D15/38; B01D61/14
Domestic Patent References:
WO2020191369A12020-09-24
WO2022066928A22022-03-31
WO2022019769A12022-01-27
Foreign References:
US20170252699A12017-09-07
EP3782646A12021-02-24
Attorney, Agent or Firm:
RAVASIO, Sara (GB)
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