Pyrazine compounds for the control of invertebrate pests Description The invention relates to compounds of formula I wherein R
1 is H, OH, C
1 -C
6 -alkyl, C
1 -C
6 -haloalkyl, C
3 -C
6 -cycloalkyl, C
3 -C
6 -halocycloalkyl, C
1 -C
5 - alkoxy, C
2 -C
4 -alkenyl, C
2 -C
4 -alkynyl, C
1 -C
4 -alkyl-C
3 -C
6 -cycloalkyl, C
1 -C
4 -alkyl-C
3 -C
6 -halo- cycloalkyl, which groups are unsubstituted, or partially or fully substituted with R
11 ; or C(=N-R
11 )R
12 , C(O)R
11a ; R
11 is CN, NO
2 , NR
12 R
13 , C(O)NH
2 , C(S)NH
2 , C(O)OH, OR
14 , Si(CH
3 )
3 ; C
1 -C
6 -alkyl; C
1 - C
6 -haloalkyl; C
2 -C
6 -alkenyl; C
2 -C
6 -haloalkenyl; C
2 -C
6 -alkynyl; C
2 -C
6 -haloalkynyl; C
3 - C
4 -cycloalkyl-C
1 -C
2 -alkyl which ring is unsubstituted or substituted with 1 or 2 halo- gen; 3- to 6-membered heterocyclyl, 5- or 6-membered hetaryl, phenyl, or phenoxy, naphthyl, naphthoxy, which rings are unsubstituted or substituted with R
3a ; R
11a is NR
12 R
13 , C(O)NH
2 , C(S)NH
2 , C(O)OH, OR
14 , Si(CH
3 )
3 ; C
1 -C
6 -haloalkyl; C
2 -C
6 - alkenyl; C
2 -C
6 -haloalkenyl; C
2 -C
6 -alkynyl; C
2 -C
6 -haloalkynyl; C
3 -C
4 -cycloalkyl-C
1 -C
2 - alkyl, which ring is unsubstituted or substituted with 1 or 2 halogen; 3- to 6-mem- bered heterocyclyl, which rings are unsubstituted or substituted with halogen, C
1 -C
3 - haloalkyl, and/or CN; R
12 , R
13 are independently from each other H, C
1 -C
4 -alkyl, C
1 -C
4 -alkoxy, C
1 -C
4 -haloal- koxy, C
1 -C
4 -haloalkyl, C
3 -C
6 -cycloalkyl, C(O)-C
1 -C
4 -alkyl, C(O)-C
1 -C
4 -haloalkyl, C(O)-C
3 -C
4 -cycloalkyl, C(O)-C
3 -C
4 -halocycloalkyl, C(O)NR
121 R
131 , S(O)
m -C
1 -C
4 - haloalkyl, S(O)
m -C
3 -C
4 -cycloalkyl, S(O)
m -C
3 -C
4 -halocycloalkyl, S(O)
m -NR
121 R
131 ; 3- to 6-membered heterocyclyl, 5- or 6-membered hetaryl, phenyl, phenoxy, phenyl- C
1 -C
4 -alkyl, naphthyl, naphthoxy, which rings are unsubstituted or substituted with R
3a ; or R
12 and R
13 , together with the nitrogen atom to which they are bound, form a 3-, 4-, 5-, 6- or 7-membered saturated, partially unsaturated or fully unsaturated heterocycle, which heterocycle may additionally contain 1 or 2 heteroatoms or heteroatom groups selected from N, O, and S(O)
m as ring members, and which heterocycle is unsubstituted or substituted with one or more substituents selected from halogen, C
1 -C
4 -alkyl, C
1 -C
4 -haloalkyl, C
1 -C
4 -alkoxy, C
1 -C
4 -haloalkoxy, and oxo; R
121 and R
131 are independently from each other hydrogen, C
1 -C
4 -alkyl, C
1 -C
4 -haloalkyl, C
3 -C
6 -cycloalkyl, C
3 -C
6 -halocycloalkyl, C
3 -C
4 -cycloalkyl-C
1 -C
2 -alkyl, C
1 -C
4 -alkoxy, C
1 -C
4 -haloalkoxy; C
1 -C
4 -alkyl-phenyl, C
1 -C
4 -alkyl-3-6-membered hetaryl, phenyl, 3- to 6-membered heterocyclyl or 5- or 6-membered hetaryl which rings are unsubsti- tuted or substituted with R
3a ; or R
121 and R
131 together with the nitrogen atom they are bound to form a 3-6 membered sat- urated, partially or fully unsaturated heterocycle, which may further contain 1 or 2 heteroatoms ring members selected from N, O and S, wherein S may be oxidized, which heterocycle is unsubstituted or substituted with halogen, C
1 -C
3 -haloalkyl, and/or CN; m is 0, 1, or 2; R
14 is H, C
1 -C
4 -alkyl, C
1 -C
4 -haloalkyl, C
3 -C
6 -cycloalkyl, C
3 -C
6 -halocycloalkyl, C
3 -C
4 -cy- cloalkyl-C
1 -C
2 -alkyl, C
3 -C
4 -halocycloalkyl-C
1 -C
2 -alkyl, C(O)-C
1 -C
4 -alkyl, C(O)-C
1 -C
4 - haloalkyl, C(O)-C
3 -C
4 -cycloalkyl, C(O)-C
3 -C
4 -halocycloalkyl, or phenyl which is un- substituted or partially or fully substituted with R
3a ; R
2 is CN, C
1- C
3 -alkyl, C
1 -C
3 -haloalkyl, C
2 -C
3 -alkynyl; R
3 is halogen, CN, NO
2 , C
1 -C
4 -alkyl, C
3 -C
6 -cycloalkyl, C
1 -C
6 -haloalkyl, C
1 -C
6 -halocycloalkyl, OR
14 , S(O)
m -R
14 ; which are unsubstituted or substituted with R
3a ; R
3a halogen, CN, NO
2 , OR
15 , C
1 -C
4 -alkyl, C
1 -C
4 -haloalkyl, C
1 -C
4 -alkoxy-C
1 -C
4 -alkyl, C
3 - C
6 -cycloalkyl, C
3 -C
6 -halocycloalkyl, S(O)
m -C
1 -C
4 -alkyl, S(O)
m -C
1 -C
4 -haloalkyl, S(O)
m - C
3 -C
4 -cycloalkyl, S(O)
m -C
3 -C
4 -halocycloalkyl, phenyl, phenyl-C
1 -C
4 -alkyl, which rings are unsubstituted or substituted with halogen, CN, NO
2 , C
1 -C
4 -alkyl, C
1 -C
4 -haloalkyl, C
1 -C
4 -alkoxy-C
1 -C
4 -alkyl, C
1 -C
4 -alkoxy, C
1 -C
4 -haloalkoxy, R
3a as substituent of cycloalkyl or heterocyclyl may also denote oxo; n is 0, 1, 2, or 3; Q is CH, CR
3 , or N; R
4 is H, OH, CN, C
1 -C
4 -alkyl, C
3 -C
6 -cycloalkyl, C
1 -C
6 -haloalkyl, C
1 -C
6 -halocycloalkyl, C
2 -C
4 - alkenyl, C
2 -C
4 -haloalkenyl, C
2 -C
4 -alkynyl, C
1 -C
4 -alkoxy, C
1 -C
4 -haloalkoxy, S(O)
m -C
1 -C
4 - alkyl, S(O)
m -C
1 -C
4 -haloalkyl, S(O)
m -C
3 -C
4 -cycloalkyl, S(O)
m -C
3 -C
4 -halocycloalkyl, NR
12 R
13 , C(O)NR
12 R
13 , C(O)OR
14 , 3- to 6-membered heterocyclyl, 5- or 6-membered hetaryl, or phenyl, which rings are unsubstituted or substituted with R
3 ; R
5 is H, OR
15 , NR
12 R
13 , or C
1 -C
6 -alkyl which is unsubstituted, or partially or fully substituted with R
11 ; R
15 is H, C
1 -C
4 -alkyl, or C
1 -C
4 -haloalkyl, C
3 -C
7 -cycloalkyl, C
3 -C
7 -halocycloalkyl, C
3 -C
7 - cycloalkenyl, C
3 -C
7 -halocycloalkenyl, which carbon chains or rings are unsubstituted or partially or fully substituted with R
11 ; or 3- to 6-membered heterocyclyl, 5- or 6- membered hetaryl, or phenyl, which rings are unsubstituted or substituted with R
3 ; and the N-oxides, stereoisomers and agriculturally or veterinarily acceptable salts thereof. The invention also provides agricultural compositions comprising at least one compound of for- mula I, a stereoisomer thereof and/or an agriculturally acceptable salt thereof and at least one liquid and/or solid carrier, especially at least one inert liquid and/or solid agriculturally accepta- ble carrier. The invention also provides a veterinary composition comprising at least one compound of for- mula I, a stereoisomer thereof and/or a veterinarily acceptable salt thereof and at least one liq- uid and/or solid carrier, especially at least one inert veterinarily liquid and/or solid acceptable carrier. The invention also provides a method for controlling invertebrate pests which method com- prises treating the pests, their food supply, their habitat or their breeding ground or a cultivated plant, plant propagation materials (such as seed), soil, area, material or environment in which the pests are growing or may grow, or the materials, cultivated plants, plant propagation materi- als (such as seed), soils, surfaces or spaces to be protected from pest attack or infestation with a pesticidally effective amount of a compound of formula I or a salt thereof as defined herein. The invention also relates to plant propagation material, in particular seed, comprising at least one compound of formula I and/or an agriculturally acceptable salt thereof. The invention further relates to a method for treating or protecting an animal from infestation or infection by parasites which comprises bringing the animal in contact with a parasiticidally effec- tive amount of a compound of formula I or a veterinarily acceptable salt thereof. Bringing the an- imal in contact with the compound I, its salt or the veterinary composition of the invention means applying or administering it to the animal. WO 2017/192385, WO2020/070049, WO2020/201079, WO2020/201398, WO2020/208036, WO2021/037614, WO2021/122656, WO2021/068179, and WO2021/069575 describe structur- ally closely related active compounds. These compounds are mentioned to be useful for com- bating invertebrate pests. Nevertheless, there remains a need for highly effective and versatile agents for combating in- vertebrate pests. It is therefore an object of the invention to provide compounds having a good pesticidal activity and showing a broad activity spectrum against a large number of different in- vertebrate pests, especially against difficult to control pests, such as insects. It has been found that these objects can be achieved by compounds of formula I as depicted and defined below, and by their stereoisomers, salts, tautomers and N-oxides, in particular their agriculturally acceptable salts. Compounds A wherein R
4 is bound via O or N (compounds of formula A.a) can be prepared from the corresponding compounds II by a carbonylation reaction, using 0.01 to 0.2 equivalents of a palladium complex, such as palladium diacetate, bis(benzonitrile)dichloropalladium, bis(dibenzylideneacetone)palladium, or tris(dibenzylideneacetone)dipalladium, and 0.01 to 0.2 equivalents of a ligand, such as triphenylphosphine, 1,1-bis(diphenylphosphino)ferrocene, or 1,3-bis(diphenylphosphino)propane, as catalysts, in the presence of 1 to 5 equivalents of a suit- able nucleophilic reagent, such as an alcohol or a primary or a secondary amine, in an inert sol- vent such as toluene, xylenes, mesitylene, MeCN, tetrahydrofurane (THF), 1,4-dioxane, dime- thylsulfoxide (DMSO), or optionally using the nucleophilic reagent as the solvent, and optionally in the presence of additives such as triethylamine, diisopropylethylamine, NaOAc, KOAc, CsOAc, Na
2 CO
3 , K
2 CO
3 , Cs
2 CO
3 , NaHCO
3 , KHCO
3 , and/or molecular sieves, at temperatures between 25°C and 180°C, preferably between 25°C and the boiling point of the solvent, and in the presence of carbon monoxide gas at pressures between 1 and 50bar (cf. Beller et al., An- gew. Chem. Int. Ed.2009, 4114 (and references therein); Takeuchi et al., J. Mol. Catal.1991, 277). In addition, using similar catalysts and additives as above, compounds I wherin X is O and R
4 is C-bound can be obtained from the corresponding compounds II by Stille reactions with alkoxyalkenylstannanes and subsequent enol ether hydrolysis (cf. H. Lin et al., Bioorg Med Chem Lett 2010, 679; Eastwood et al., Bioorg Med Chem Lett 2010, 1697). In compounds A the variables are as defined for formula I. Compounds II are known from WO2020070049. Compounds I can be obtained by condensation of a compound A, with an amine, hydroxyla- mine, hydrazine, or derivatives thereof, in a solvent such as (or solvent mixture composed of) dichloromethane (DCM), chloroform, benzene, toluene, xylenes, mesitylene, 1,4-dioxane, meth- anol, ethanol, 2-propanol, and/or water, at temperatures from 0°C to the boiling point of the sol- vent or solvent mixture, and optionally with concomitant water removal, e.g. by using a Dean- Stark apparatus, or molecular sieves, or salts such as MgSO
4 or Na
2 SO
4 , and optionally in the presence of 0.05 to 1 equivalent of an additive such as formic acid, acetic acid, hydrochloric acid, p-toluenesulfonic acid, NaOAc, KOAc, NaOH, or KOH (cf. G. Heinisch et al., Heterocycles 1996, 151; J. Liu, Bioorg Med Chem 2008, 1096, provided that R
4 is not O- or N-bound). In general, compounds I wherein R
5 is OH (compounds of formula I.d) can be converted to the corresponding compounds I wherein R
5 is OR
15 (compounds of formula I.e) with alkylating rea- gents such as alkyl halides, alkyl tosylates, or alkyl mesylates and following procedures known from literature (cf. Khomutov et al., Amino Acids 2010, 38, 509; Abele et al., Synthetic Commu- nications 1998, 28, 2621; Kocak et al., Synthetic Communications 2007, 37, 1155). Compounds I wherein R
4 is NH
2 (compounds of formula I.b1) can be obtained from com- pounds III by addition of a suitable nucleophile, such as hydroxylamine, hydrazine, or a deriva- tive thereof, optionally in the presence of 1 to 2 equivalents of a base such as NaOH, KOH, Na
2 CO
3 , K
2 CO
3 , or Cs
2 CO
3 , and in a solvent such as (or solvent mixture composed of) metha- nol, ethanol, 2-propanol, and/or water, and at temperatures ranging from 0°C to the boiling point of the solvent or solvent mixture (cf. Tiemann, Chem. Ber.1884, 17, 126; Gobis et al., Acta Pol Pharm (Drug Research) 2006, 39). Compounds III can be obtained by reaction of compounds II with 1 to 2 equivalents of Zn(CN)
2 in the presence of 0.01 to 0.2 equivalents of a transition-metal complex, such as palladium diac- etate, palladium trifluoroacetate, tris(dibenzylideneacetone)dipalladium, tetrakis(triphenylphos- phine)palladium, or nickel dichloride, and 0.01 to 0.2 equivalents of a ligand, such as 2-[di(tert- butyl)phosphino]-1,1´-binaphthyl, 1,1-bis(diphenylphosphino)ferrocene, or BINAP, as catalysts, and 0.1 to 0.5 equivalents of zinc powder or zinc flakes as a cocatalyst, and optionally with 1 to 3 equivalents of a base, such as 4-(dimethylamino)pyridine or sodium tert-butoxide, in a solvent such as dimethylformamide (DMF), N,N-dimethylacetamide (DMA), or acetonitrile, at tempera- tures between 25°C and 150°C, preferably between 25°C and the boiling point of the solvent (cf. A. Littke et al., Org. Lett.2007, 1711). Compounds I wherein R
5 is OR
15 and R
4 is NH
2 (compounds I.e1) can be converted to com- pounds I wherein R
5 is OR
15 and R
4 is NR
12 R
13 (compounds i.e2) in two steps by reaction with sodium nitrite in aqueous HCl followed by substitution of the chloride with HNR
12 R
13 (cf. K. Go- bis et al., Acta Pol Pharm (Drug Research) 2006, 39; A. M. Martsynkevich et al., Russ. Chem. Bull. Int. Ed.2011, 521). If individual compounds I cannot be obtained by the routes described above, they can be pre- pared by derivatization of other compounds I. The reaction mixtures are worked up in a customary manner, for example by mixing with wa- ter, extracting with an appropriate organic solvent, separating the phases and, if appropriate, chromatographic purification of the crude products. Some of the intermediates and end products are obtained in the form of colourless or slightly brownish viscous oils which are purified or freed from volatile components under reduced pressure and at moderately elevated temperature. If the intermediates and end products are obtained as solids, purification can also be carried out by recrystallization or digestion. However, if the synthesis yields mixtures of isomers, a separation is generally not necessarily required since in some cases the individual isomers can be interconverted during work-up for use or during application (for example under the action of light, acids or bases). Such conver- sions may also take place after use, for example in the treatment of plants in the treated plant, or in the pest to be controlled. The organic moieties groups mentioned in the above definitions of the variables are - like the term halogen - collective terms for individual listings of the individual group members. The prefix C
n -C
m indicates in each case the possible number of carbon atoms in the group. The term “partially or fully substituted” by a radical means that in general the group is substi- tuted with same or different radicals. The term “halogen” denotes in each case fluorine, bromine, chlorine, or iodine, in particular flu- orine, chlorine, or bromine. The term "alkyl" as used herein and in the alkyl moieties of alkylamino, alkylcarbonyl, alkylthio, alkylsulfinyl, alkylsulfonyl and alkoxyalkyl denotes in each case a straight-chain or branched al- kyl group having usually from 1 to 10 carbon atoms, frequently from 1 to 6 carbon atoms, prefer- ably 1 to 4 carbon atoms, more preferably from 1 to 3 carbon atoms. Examples of an alkyl group are methyl (Me), ethyl (Et), n-propyl (n-Pr), iso-propyl, n-butyl, 2-butyl, iso-butyl, tert-butyl, n- pentyl, 1-methylbutyl, 2-methylbutyl, 3-methylbutyl, 2,2-dimethylpropyl, 1-ethylpropyl, n-hexyl, 1,1-dimethylpropyl, 1,2-dimethylpropyl, 1-methylpentyl, 2-methylpentyl, 3-methylpentyl, 4- methylpentyl, 1,1-dimethylbutyl, 1,2-dimethylbutyl, 1,3-dimethylbutyl, 2,2-dimethylbutyl, 2,3-di- methylbutyl, 3,3-dimethylbutyl, 1-ethylbutyl, 2-ethylbutyl, 1,1,2-trimethylpropyl, 1,2,2-trime- thylpropyl, 1-ethyl-1-methylpropyl, and 1-ethyl-2-methylpropyl. The term "haloalkyl" as used herein and in the haloalkyl moieties of haloalkylcarbonyl, haloal- koxycarbonyl, haloalkylthio, haloalkylsulfonyl, haloalkylsulfinyl, haloalkoxy and haloalkoxyalkyl, denotes in each case a straight-chain or branched alkyl group having usually from 1 to 10 car- bon atoms, frequently from 1 to 6 carbon atoms, preferably from 1 to 4 carbon atoms, wherein the hydrogen atoms of this group are partially or totally replaced with halogen atoms. Preferred haloalkyl moieties are selected from C
1 -C
4 -haloalkyl, more preferably from C
1 -C
3 -haloalkyl or C
1 -C
2 -haloalkyl, in particular from C
1 -C
2 -fluoroalkyl such as fluoromethyl, difluoromethyl, trifluoromethyl, 1-fluoroethyl, 2-fluoroethyl, 2,2-difluoroethyl, 2,2,2-trifluoroethyl, pentafluoro- ethyl, and the like. The term "alkoxy" as used herein denotes in each case a straight-chain or branched alkyl group which is bonded via an oxygen atom and has usually from 1 to 10 carbon atoms, fre- quently from 1 to 6 carbon atoms, preferably 1 to 4 carbon atoms. Examples of an alkoxy group are methoxy, ethoxy, n-propoxy, iso-propoxy, n-butyloxy, 2-butyloxy, iso-butyloxy, tert.-butyloxy, and the like. The term "alkoxyalkyl" as used herein refers to alkyl usually comprising 1 to 10, frequently 1 to 4, preferably 1 to 2 carbon atoms, wherein 1 carbon atom carries an alkoxy radical usually com- prising 1 to 4, preferably 1 or 2 carbon atoms as defined above. Examples are CH
2 OCH
3 , CH
2 - OC
2 H
5 , 2-(methoxy)ethyl, and 2-(ethoxy)ethyl. The term "haloalkoxy" as used herein denotes in each case a straight-chain or branched alkoxy group having from 1 to 10 carbon atoms, frequently from 1 to 6 carbon atoms, preferably 1 to 4 carbon atoms, wherein the hydrogen atoms of this group are partially or totally replaced with halogen atoms, in particular fluorine atoms. Preferred haloalkoxy moieties include C
1 -C
4 - haloalkoxy, in particular C
1 -C
2 -fluoroalkoxy, such as fluoromethoxy, difluoromethoxy, trifluoro- methoxy, 1-fluoroethoxy, 2-fluoroethoxy, 2,2-difluoroethoxy, 2,2,2-trifluoroethoxy, 2-chloro-2-flu- oroethoxy, 2-chloro-2,2-difluoro-ethoxy, 2,2dichloro-2-fluorethoxy, 2,2,2-trichloroethoxy, penta- fluoroethoxy and the like. The term "alkylthio "(alkylsulfanyl: -S-alkyl)" as used herein refers to a straight-chain or branched saturated alkyl group having 1 to 10 carbon atoms, preferably 1 to 4 carbon atoms (= C
1 -C
4 -alkylthio), more preferably 1 to 3 carbon atoms, which is attached via a sulfur atom. The term "haloalkylthio" as used herein refers to an alkylthio group as mentioned above wherein the hydrogen atoms are partially or fully substituted by fluorine, chlorine, bromine and/or iodine. The term "alkylsulfinyl" (alkylsulfoxyl: -S(=O)-C
1 -C
6 -alkyl), as used herein refers to a straight- chain or branched saturated alkyl group (as mentioned above) having 1 to 10 carbon atoms, preferably 1 to 4 carbon atoms (= C
1 -C
4 -alkylsulfinyl), more preferably 1 to 3 carbon atoms bonded through the sulfur atom of the sulfinyl group at any position in the alkyl group. The term "haloalkylsulfinyl" as used herein refers to an alkylsulfinyl group as mentioned above wherein the hydrogen atoms are partially or fully substituted by fluorine, chlorine, bromine and/or iodine. The term "alkylsulfonyl" (S(=O)
2 -alkyl) as used herein refers to a straight-chain or branched saturated alkyl group having 1 to 10 carbon atoms, preferably 1 to 4 carbon atoms (= C
1 -C
4 -al- kylsulfonyl), preferably 1 to 3 carbon atoms, which is bonded via the sulfur atom of the sulfonyl group at any position in the alkyl group. The term "haloalkylsulfonyl" as used herein refers to an alkylsulfonyl group as mentioned above wherein the hydrogen atoms are partially or fully substituted by fluorine, chlorine, bro- mine and/or iodine. The term "alkylcarbonyl" refers to an alkyl group as defined above, which is bonded via the carbon atom of a carbonyl group (C=O) to the remainder of the molecule. The term "haloalkylcarbonyl" refers to an alkylcarbonyl group as mentioned above, wherein the hydrogen atoms are partially or fully substituted by fluorine, chlorine, bromine and/or iodine. The term "alkoxycarbonyl" refers to an alkylcarbonyl group as defined above, which is bonded via an oxygen atom to the remainder of the molecule. The term "haloalkoxycarbonyl” refers to an alkoxycarbonyl group as mentioned above, wherein the hydrogen atoms are partially or fully substituted by fluorine, chlorine, bromine and/or iodine. The term "alkenyl" as used herein denotes in each case a singly unsaturated hydrocarbon rad- ical having usually 2 to 10, frequently 2 to 6, preferably 2 to 4 carbon atoms, e.g. vinyl, allyl (2- propen-1-yl), 1-propen-1-yl, 2-propen-2-yl, methallyl (2-methylprop-2-en-1-yl), 2-buten-1-yl, 3- buten-1-yl, 2-penten-1-yl, 3-penten-1-yl, 4-penten-1-yl, 1-methylbut-2-en-1-yl, 2-ethylprop-2-en- 1-yl and the like. The term "haloalkenyl" as used herein refers to an alkenyl group as defined above, wherein the hydrogen atoms are partially or totally replaced with halogen atoms. The term "alkynyl" as used herein denotes in each case a singly unsaturated hydrocarbon rad- ical having usually 2 to 10, frequently 2 to 6, preferably 2 to 4 carbon atoms, e.g. ethynyl, pro- pargyl (2-propyn-1-yl), 1-propyn-1-yl, 1-methylprop-2-yn-1-yl), 2-butyn-1-yl, 3-butyn-1-yl, 1- pentyn-1-yl, 3-pentyn-1-yl, 4-pentyn-1-yl, 1-methylbut-2-yn-1-yl, 1-ethylprop-2-yn-1-yl and the like. The term "haloalkynyl" as used herein refers to an alkynyl group as defined above, wherein the hydrogen atoms are partially or totally replaced with halogen atoms. The term "cycloalkyl" as used herein and in the cycloalkyl moieties of cycloalkoxy and cycloal- kylthio denotes in each case a mono- or bicyclic, preferably monocyclic, cycloaliphatic radical having usually from 3 to 10 or from 3 to 6 carbon atoms, such as cyclopropyl (cC
3 H
5 ), cyclobutyl (cC
4 H
7 ), cyclopentyl (cC
5 H
9 ), cyclohexyl (cC
6 H
11 ), cycloheptyl, cyclooctyl, cyclononyl, and cy- clodecyl, or cyclopropyl, cyclobutyl, cyclopentyl, and cyclohexyl. The term "halocycloalkyl" as used herein and in the halocycloalkyl moieties of halocycloalkoxy and halocycloalkylthio denotes in each case a mono- or bicyclic, preferably monocyclic, cycloali- phatic radical having usually from 3 to 10 C atoms or 3 to 6 C atoms, wherein at least one, e.g. 1, 2, 3, 4 or 5 of the hydrogen atoms, are replaced by halogen, in particular by fluorine or chlo- rine. Examples are 1- and 2-fluorocyclopropyl, 1,2-, 2,2- and 2,3-difluorocyclopropyl, 1,2,2-tri- fluorocyclopropyl, 2,2,3,3-tetrafluorocyclpropyl, 1- and 2-chlorocyclopropyl, 1,2-, 2,2- and 2,3- dichlorocyclopropyl, 1,2,2-trichlorocyclopropyl, 2,2,3,3-tetrachlorocyclpropyl, 1-,2- and 3- fluorocyclopentyl, 1,2-, 2,2-, 2,3-, 3,3-, 3,4-, 2,5-difluorocyclopentyl, 1-,2- and 3-chlorocyclopen- tyl, 1,2-, 2,2-, 2,3-, 3,3-, 3,4-, 2,5-dichlorocyclopentyl and the like. The term “cycloalkenyl” as used herein and in the cycloalkenyl moieties of cycloalkenyloxy and cycloalkenylthio denotes in each case a mono- or bicyclic, preferably monocyclic, singly unsatu- rated non-aromatic radical having usually from 3 to 10, e.g.3 or 4 or from 5 to 10 carbon atoms, preferably from 3- to 8 carbon atoms. Examples are cyclopenten-1-yl, and cyclohexen-1-yl. The term “halocycloalkenyl” as used herein and in the halocycloalkenyl moieties of halocyclo- alkenyloxy and halocycloalkenylthio denotes in each case a mono- or bicyclic, preferably mono- cyclic, singly unsaturated non-aromatic radical having usually from 3 to 10, e.g.3 or 4 or from 5 to 10 carbon atoms, preferably from 3- to 8 carbon atoms, wherein at least one, e.g.1, 2, 3, 4 or 5 of the hydrogen atoms, are replaced by halogen, in particular by fluorine or chlorine. Exam- ples are 3,3-difluorocyclopropen-1-yl and 3,3-dichlorocyclopropen-1-yl. The term "cycloalkenylalkyl" refers to a cycloalkenyl group as defined above which is bonded via an alkyl group, such as a C
1 -C
5 -alkyl group or a C
1 -C
4 -alkyl group, in particular a methyl group (= cycloalkenylmethyl), to the remainder of the molecule. The term “carbocycle” or “carbocyclyl” includes in general a 3- to 12-membered, preferably a 3- to 8-membered or a 5- to 8-membered, more preferably a 5- or 6-membered mono-cyclic, non-aromatic ring comprising 3 to 12, preferably 3 to 8 or 5 to 8, more preferably 5 or 6 carbon atoms. Preferably, the term “carbocycle” covers cycloalkyl and cycloalkenyl groups as defined above. The term “heterocycle” or "heterocyclyl" includes in general 3- to 12-membered, preferably 3- to 6-membered, in particular 6-membered monocyclic heterocyclic non-aromatic radicals. The heterocyclic non-aromatic radicals usually comprise 1, 2, 3, 4 or 5, preferably 1, 2 or 3 heteroa- toms selected from N, O, and S as ring members, wherein S-atoms as ring members may be present as S, SO, or SO
2 . Examples of 5- or 6-membered heterocyclic radicals comprise satu- rated or unsaturated, non-aromatic heterocyclic rings, such as oxiranyl, oxetanyl, thietanyl, thietanyl-S-oxid (S-oxothietanyl), thietanyl-S-dioxid (S-dioxothiethanyl), pyrrolidinyl, pyrrolinyl, pyrazolinyl, tetrahydrofuranyl, dihydrofuranyl, 1,3-dioxolanyl, thiolanyl, S-oxothiolanyl, S-dioxo- thiolanyl, dihydrothienyl, S-oxodihydrothienyl, S-dioxodihydrothienyl, oxazolidinyl, oxazolinyl, thi- azolinyl, oxathiolanyl, piperidinyl, piperazinyl, pyranyl, dihydropyranyl, tetrahydropyranyl, 1,3- and 1,4-dioxanyl, thiopyranyl, S.oxothiopyranyl, S-dioxothiopyranyl, dihydrothiopyranyl, S-oxodi- hydrothiopyranyl, S-dioxodihydrothiopyranyl, tetrahydrothiopyranyl, S-oxotetrahydrothiopyranyl, S-dioxotetrahydrothiopyranyl, morpholinyl, thiomorpholinyl, S-oxothiomorpholinyl, S-dioxothio- morpholinyl, thiazinyl and the like. Examples for heterocyclic ring also comprising 1 or 2 car- bonyl groups as ring members comprise pyrrolidin-2-onyl, pyrrolidin-2,5-dionyl, imidazolidin-2- onyl, oxazolidin-2-onyl, thiazolidin-2-only, and the like. The term "hetaryl" includes monocyclic 5- or 6-membered heteroaromatic radicals comprising as ring members 1, 2, 3 or 4 heteroatoms selected from N, O, and S. Examples of 5- or 6-mem- bered heteroaromatic radicals include pyridyl, i.e.2-, 3-, or 4-pyridyl, pyrimidinyl, i.e.2-, 4- or 5- pyrimidinyl, pyrazinyl, pyridazinyl, i.e.3- or 4-pyridazinyl, thienyl, i.e.2- or 3-thienyl, furyl, i.e.2- or 3-furyl, pyrrolyl, i.e.2- or 3-pyrrolyl, oxazolyl, i.e.2-, 3- or 5-oxazolyl, isoxazolyl, i.e.3-, 4- or 5-isoxazolyl, thiazolyl, i.e.2-, 3- or 5-thiazolyl, isothiazolyl, i.e.3-, 4- or 5-isothiazolyl, pyrazolyl, i.e.1-, 3-, 4- or 5-pyrazolyl, i.e.1-, 2-, 4- or 5-imidazolyl, oxadiazolyl, e.g.2- or 5-[1,3,4]oxadia- zolyl, 4- or 5-(1,2,3-oxadiazol)yl, 3- or 5-(1,2,4-oxadiazol)yl, 2- or 5-(1,3,4-thiadiazol)yl, thiadia- zolyl, e.g.2- or 5-(1,3,4-thiadiazol)yl, 4- or 5-(1,2,3-thiadiazol)yl, 3- or 5-(1,2,4-thiadiazol)yl, tria- zolyl, e.g.1H-, 2H- or 3H-1,2,3-triazol-4-yl, 2H-triazol-3-yl, 1H-, 2H-, or 4H-1,2,4-triazolyl and te- trazolyl, i.e.1H- or 2H-tetrazolyl. The term "hetaryl" also includes bicyclic 8 to 10-membered heteroaromatic radicals comprising as ring members 1, 2 or 3 heteroatoms selected from N, O, and S, wherein a 5- or 6-membered heteroaromatic ring is fused to a phenyl ring or to a 5- or 6- membered heteroaromatic radical. Examples of a 5- or 6-membered heteroaromatic ring fused to a phenyl ring or to a 5- or 6-membered heteroaromatic radical include benzofuranyl, benzo- thienyl, indolyl, indazolyl, benzimidazolyl, benzoxathiazolyl, benzoxadiazolyl, benzothiadiazolyl, benzoxazinyl, chinolinyl, isochinolinyl, purinyl, 1,8-naphthyridyl, pteridyl, pyrido[3,2-d]pyrimidyl or pyridoimidazolyl and the like. These fused hetaryl radicals may be bonded to the remainder of the molecule via any ring atom of 5- or 6-membered heteroaromatic ring or via a carbon atom of the fused phenyl moiety. The terms "heterocyclylalkyl" and "hetarylalkyl" refer to heterocyclyl or hetaryl, respectively, as defined above which are bonded via a C
1 -C
5 -alkyl group or a C
1 -C
4 -alkyl group, in particular a methyl group (= heterocyclylmethyl or hetarylmethyl, respectively), to the remainder of the mole- cule. The term “arylalkyl” and "phenylalkyl" refer to aryl as defined above and phenyl, respectively, which are bonded via C
1 -C
5 -alkyl group or a C
1 -C
4 -alkyl group, in particular a methyl group (= arylmethyl or phenylmethyl), to the remainder of the molecule, examples including benzyl, 1- phenylethyl, 2-phenylethyl, 2-phenoxyethyl etc. The terms “alkylene”, “cycloalkylene”, “heterocycloalkylene”, “alkenylene”, “cycloalkenylene”, “heterocycloalkenylene” and “alkynylene” refer to alkyl, cycloalkyl, heterocycloalkyl, alkenyl, cy- cloalkenyl, heterocycloalkenyl and alkynyl as defined above, respectively, which are bonded to the remainder of the molecule, via two atoms, preferably via two carbon atoms, of the respec- tive group, so that they represent a linker between two moieties of the molecule. In a particular embodiment, the variables of the compounds of the formula I have the following meanings, these meanings, both on their own and in combination with one another, being par- ticular embodiments of the compounds of the formula I. Embodiments and preferred compounds of the invention for use in pesticidal methods and for insecticidal application purposes are outlined in the following paragraphs. With respect to the variables, the particularly preferred embodiments of the intermediates cor- respond to those of the compounds of the formula I. In a preferred embodiment, the compounds I are present in form of a mixture of compounds I.A and I.B, wherein compound I.A with S-configuration of the carbon atom neighboring the ni- trogen is present in an amount of more than 50% by weight, in particular of at least 70% by weight, more particularly of at least 85% by weight, specifically of at least 90% by weight, based on the total weight of compounds I.A and I.B. In one particularly preferred embodiment of the invention, the method comprises the step of contacting the plant, parts of it, its propagation material, the pests, their food supply, habitat or breeding grounds with a pesticidally effective amount of a compound of formula I.A. Preferably R
1 is H, C
1 -C
6 -alkyl, C
3 -C
4 -alkenyl, C
3 -C
4 -alkynyl, C
3 -C
6 -cycloalkyl, or C
1 -C
4 -alkyl- C
3 -C
6 -cycloalkyl. Particularly R
1 is H or CH
2 -cC
3 H
5 . Preferably R
2 is CH
3 . R
3 is preferably halogen, CN, C
1 -C
4 -haloalkyl, C
1 -C
4 -haloalkoxy, C
3 -C
4 -cycloalkyl, C
3 -C
4 -halo- cycloalkyl, S(O)
m -C
1 -C
4 -alkyl, S(O)
m -C
1 -C
4 -haloalkyl, S(O)
m -C
3 -C
4 -cycloalkyl, S(O)
m -C
3 -C
4 -halo- cycloalkyl. Index m in R
3 is preferably 2. Index n is preferably 2. In one embodiment Q is CH or CR
3 , preferably CH. Such compounds correspond to formula I.1 In another embodiment Q is N. Such compounds correspond to formula I.2 R
3 groups stand preferably in positions 3 and 5. In another embodiment R
3 is preferably halogen, CN, C
1 -C
4 -haloalkyl, C
1 -C
4 -haloalkoxy, C
3 - C
4 -cycloalkyl, C
3 -C
4 -halocycloalkyl, S(O)
m -C
1 -C
4 -alkyl, S(O)
m -C
1 -C
4 -haloalkyl, S(O)
m -C
3 -C
4 -cy- cloalkyl, S(O)
m -C
3 -C
4 -halocycloalkyl, or S(O)m-R
14 , wherein R
14 is phenyl, which is partially substituted with R
3a . In another embodiment of formula I compounds R
3 is halogen, CN, NO
2 , C
1 -C
4 -alkyl, C
3 -C
6 - cycloalkyl, C
1 -C
6 -haloalkyl, C
1 -C
6 -halocycloalkyl, OR
14 , S(O)
m -R
14 ; wherein rings are unsubsti- tuted or substituted with R
11 . In another embodiment of formula I compounds R
3 is halogen, CN, NO
2 , C
1 -C
4 -alkyl, C
3 -C
6 - cycloalkyl, C
1 -C
6 -haloalkyl, C
1 -C
6 -halocycloalkyl, OR
14 , S(O)
m -R
14 ; wherein rings are unsubsti- tuted or substituted with one or more CN, OH, C
1 -C
4 -alkoxy. In another embodiment of formula I compounds R
3 is C
3 -C
6 -cycloalkyl unsubstituted or substi- tuted with one or more CN, OH, C
1 -C
4 -alkoxy. R
4 is preferably H, C
1 -C
3 -alkyl, or C
1 -C
3 -haloalkyl. In another embodiment R
4 is H, C
1 -C
3 -alkyl, C
1 -C
3 -haloalkyl, or NR
12 R
13 wherein R
12 and R
13 are independently from each other H or C
1 -C
3 -alkyl. R
5 is preferably OH, C
1 -C
3 -alkoxy, or C
1 -C
3 -haloalkoxy. In a preferred embodiment R
5 is OH, C
1 -C
3 -alkoxy, C
1 -C
3 -haloalkoxy, or NR
12 R
13 , wherein R
12 and R
13 are independently from each other H or C(O)NR
121 R
131 , with R
121 , and R
131 being prefer- ably independently from each other H, C
1 -C
3 -alkyl, or C
3 -C
4 -cycloalkyl-C
1 -C
2 -alkyl. In another preferred embodiment R
5 is NR
12 R
13 , wherein R
12 and R
13 form, together with the N atom they are bound to, a 4- to 7-membered heterocycle unsubstituted or substituted with R
3a , wherein R
3a is preferably halogen, C
1 -C
4 -alkyl, C
1 -C
4 -haloalkyl, or oxo. R
5 is present as E-/Z-isomers of formula I. The E-isomer is preferred, particularly in formula I compounds wherein R
5 is OR
15 and R
4 is H or alkyl, such as CH
3 . In particular with a view to their use, preference is given to the compounds of formula I com- piled in the tables below, which compounds correspond to formula I.1*, and I.2*, resp.. Each of the groups mentioned for a substituent in the tables is furthermore per se, independently of the combination in which it is mentioned, a particularly preferred aspect of the substituent in ques- tion. Table 1 Compounds of formula I.1* in which R
1 is H, R
4 is H, and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 2 Compounds of formula I.1* in which R
1 is CH
3 , R
4 is H, and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 3 Compounds of formula I.1* in which R
1 is C
2 H
5 , R
4 is H, and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 4 Compounds of formula I.1* in which R
1 is CH
2 -cC
3 H
5 , R
4 is H, and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 5 Compounds of formula I.1* in which R
1 is CH
2 -cC
5 H
9 , R
4 is H, and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 6 Compounds of formula I.1* in which R
1 is CH
2 CH=CH
2 , R
4 is H, and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 7 Compounds of formula I.1* in which R
1 is CH
2 C≡CH, R
4 is H, and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 8 Compounds of formula I.1* in which R
1 is H, R
4 is CN, and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 9 Compounds of formula I.1* in which R
1 is CH
3 , R
4 is CN, and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 10 Compounds of formula I.1* in which R
1 is C
2 H
5 , R
4 is CN, and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 11 Compounds of formula I.1* in which R
1 is CH
2 -cC
3 H
5 , R
4 is CN, and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 12 Compounds of formula I.1* in which R
1 is CH
2 -cC
5 H
9 , R
4 is CN, and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 13 Compounds of formula I.1* in which R
1 is CH
2 CH=CH
2 , R
4 is CN, and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 14 Compounds of formula I.1* in which R
1 is CH
2 C≡CH, R
4 is CN, and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 15 Compounds of formula I.1* in which R
1 is H, R
4 is CH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 16 Compounds of formula I.1* in which R
1 is CH
3 , R
4 is CH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 17 Compounds of formula I.1* in which R
1 is C
2 H
5 , R
4 is CH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 18 Compounds of formula I.1* in which R
1 is CH
2 -cC
3 H
5 , R
4 is CH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 19 Compounds of formula I.1* in which R
1 is CH
2 -cC
5 H
9 , R
4 is CH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 20 Compounds of formula I.1* in which R
1 is CH
2 CH=CH
2 , R
4 is CH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 21 Compounds of formula I.1* in which R
1 is CH
2 C≡CH, R
4 is CH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 22 Compounds of formula I.1* in which R
1 is H, R
4 is C
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 23 Compounds of formula I.1* in which R
1 is CH
3 , R
4 is C
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 24 Compounds of formula I.1* in which R
1 is C
2 H
5 , R
4 is C
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 25 Compounds of formula I.1* in which R
1 is CH
2 -cC
3 H
5 , R
4 is C
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 26 Compounds of formula I.1* in which R
1 is CH
2 -cC
5 H
9 , R
4 is C
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 27 Compounds of formula I.1* in which R
1 is CH
2 CH=CH
2 , R
4 is C
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 28 Compounds of formula I.1* in which R
1 is CH
2 C≡CH, R
4 is C
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 29 Compounds of formula I.1* in which R
1 is H, R
4 is CH
2 CH
2 CH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 30 Compounds of formula I.1* in which R
1 is CH
3 , R
4 is CH
2 CH
2 CH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 31 Compounds of formula I.1* in which R
1 is C
2 H
5 , R
4 is CH
2 CH
2 CH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 32 Compounds of formula I.1* in which R
1 is CH
2 -cC
3 H
5 , R
4 is CH
2 CH
2 CH
3 , and the combination of X and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 33 Compounds of formula I.1* in which R
1 is CH
2 -cC
5 H
9 , R
4 is CH
2 CH
2 CH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 34 Compounds of formula I.1* in which R
1 is CH
2 CH=CH
2 , R
4 is CH
2 CH
2 CH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 35 Compounds of formula I.1* in which R
1 is CH
2 C≡CH, R
4 is CH
2 CH
2 CH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 36 Compounds of formula I.1* in which R
1 is H, R
4 is CH(CH
3 )
2 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 37 Compounds of formula I.1* in which R
1 is CH
3 , R
4 is CH(CH
3 )
2 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 38 Compounds of formula I.1* in which R
1 is C
2 H
5 , R
4 is CH(CH
3 )
2 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 39 Compounds of formula I.1* in which R
1 is CH
2 -cC
3 H
5 , R
4 is CH(CH
3 )
2 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 40 Compounds of formula I.1* in which R
1 is CH
2 -cC
5 H
9 , R
4 is CH(CH
3 )
2 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 41 Compounds of formula I.1* in which R
1 is CH
2 CH=CH
2 , R
4 is CH(CH
3 )
2 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 42 Compounds of formula I.1* in which R
1 is CH
2 C≡CH, R
4 is CH(CH
3 )
2 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 43 Compounds of formula I.1* in which R
1 is H, R
4 is C(=O)NH
2 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 44 Compounds of formula I.1* in which R
1 is CH
3 , R
4 is C(=O)NH
2 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 45 Compounds of formula I.1* in which R
1 is C
2 H
5 , R
4 is C(=O)NH
2 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 46 Compounds of formula I.1* in which R
1 is CH
2 -cC
3 H
5 , R
4 is C(=O)NH
2 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 47 Compounds of formula I.1* in which R
1 is CH
2 -cC
5 H
9 , R
4 is C(=O)NH
2 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 48 Compounds of formula I.1* in which R
1 is CH
2 CH=CH
2 , R
4 is C(=O)NH
2 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 49 Compounds of formula I.1* in which R
1 is CH
2 C≡CH, R
4 is C(=O)NH
2 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 50 Compounds of formula I.1* in which R
1 is H, R
4 is C(=O)NHCH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 51 Compounds of formula I.1* in which R
1 is CH
3 , R
4 is C(=O)NHCH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 52 Compounds of formula I.1* in which R
1 is C
2 H
5 , R
4 is C(=O)NHCH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 53 Compounds of formula I.1* in which R
1 is CH
2 -cC
3 H
5 , R
4 is C(=O)NHCH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 54 Compounds of formula I.1* in which R
1 is CH
2 -cC
5 H
9 , R
4 is C(=O)NHCH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 55 Compounds of formula I.1* in which R
1 is CH
2 CH=CH
2 , R
4 is C(=O)NHCH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 56 Compounds of formula I.1* in which R
1 is CH
2 C≡CH, R
4 is C(=O)NHCH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 57 Compounds of formula I.1* in which R
1 is H, R
4 is C(=O)NHC
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 58 Compounds of formula I.1* in which R
1 is CH
3 , R
4 is C(=O)NHC
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 59 Compounds of formula I.1* in which R
1 is C
2 H
5 , R
4 is C(=O)NHC
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 60 Compounds of formula I.1* in which R
1 is CH
2 -cC
3 H
5 , R
4 is C(=O)NHC
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 61 Compounds of formula I.1* in which R
1 is CH
2 -cC
5 H
9 , R
4 is C(=O)NHC
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 62 Compounds of formula I.1* in which R
1 is CH
2 CH=CH
2 , R
4 is C(=O)NHC
2 H
5 , and the combina- tion of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 63 Compounds of formula I.1* in which R
1 is CH
2 C≡CH, R
4 is C(=O)NHC
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 64 Compounds of formula I.1* in which R
1 is H, R
4 is C(=O)N(CH
3 )
2 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 65 Compounds of formula I.1* in which R
1 is CH
3 , R
4 is C(=O)N(CH
3 )
2 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 66 Compounds of formula I.1* in which R
1 is C
2 H
5 , R
4 is C(=O)N(CH
3 )
2 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 67 Compounds of formula I.1* in which R
1 is CH
2 -cC
3 H
5 , R
4 is C(=O)N(CH
3 )
2 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 68 Compounds of formula I.1* in which R
1 is CH
2 -cC
5 H
9 , R
4 is C(=O)N(CH
3 )
2 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 69 Compounds of formula I.1* in which R
1 is CH
2 CH=CH
2 , R
4 is C(=O)N(CH
3 )
2 , and the combina- tion of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 70 Compounds of formula I.1* in which R
1 is CH
2 C≡CH, R
4 is C(=O)N(CH
3 )
2 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 71 Compounds of formula I.1* in which R
1 is H, R
4 is C(=O)N(CH
3 )C
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 72 Compounds of formula I.1* in which R
1 is CH
3 , R
4 is C(=O)N(CH
3 )C
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 73 Compounds of formula I.1* in which R
1 is C
2 H
5 , R
4 is C(=O)N(CH
3 )C
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 74 Compounds of formula I.1* in which R
1 is CH
2 -cC
3 H
5 , R
4 is C(=O)N(CH
3 )C
2 H
5 , and the combina- tion of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 75 Compounds of formula I.1* in which R
1 is CH
2 -cC
5 H
9 , R
4 is C(=O)N(CH
3 )C
2 H
5 , and the combina- tion of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 76 Compounds of formula I.1* in which R
1 is CH
2 CH=CH
2 , R
4 is C(=O)N(CH
3 )C
2 H
5 , and the combi- nation of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 77 Compounds of formula I.1* in which R
1 is CH
2 C≡CH, R
4 is C(=O)N(CH
3 )C
2 H
5 , and the combina- tion of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 78 Compounds of formula I.1* in which R
1 is H, R
4 is C(=O)OCH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 79 Compounds of formula I.1* in which R
1 is CH
3 , R
4 is C(=O)OCH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 80 Compounds of formula I.1* in which R
1 is C
2 H
5 , R
4 is C(=O)OCH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 81 Compounds of formula I.1* in which R
1 is CH
2 -cC
3 H
5 , R
4 is C(=O)OCH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 82 Compounds of formula I.1* in which R
1 is CH
2 -cC
5 H
9 , R
4 is C(=O)OCH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 83 Compounds of formula I.1* in which R
1 is CH
2 CH=CH
2 , R
4 is C(=O)OCH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 84 Compounds of formula I.1* in which R
1 is CH
2 C≡CH, R
4 is C(=O)OCH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 85 Compounds of formula I.1* in which R
1 is H, R
4 is C(=O)OC
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 86 Compounds of formula I.1* in which R
1 is CH
3 , R
4 is C(=O)OC
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 87 Compounds of formula I.1* in which R
1 is C
2 H
5 , R
4 is C(=O)OC
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 88 Compounds of formula I.1* in which R
1 is CH
2 -cC
3 H
5 , R
4 is C(=O)OC
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 89 Compounds of formula I.1* in which R
1 is CH
2 -cC
5 H
9 , R
4 is C(=O)OC
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 90 Compounds of formula I.1* in which R
1 is CH
2 CH=CH
2 , R
4 is C(=O)OC
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 91 Compounds of formula I.1* in which R
1 is CH
2 C≡CH, R
4 is C(=O)OC
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 92 Compounds of formula I.1* in which R
1 is H, R
4 is NH
2 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 93 Compounds of formula I.1* in which R
1 is CH
3 , R
4 is NH
2 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 94 Compounds of formula I.1* in which R
1 is C
2 H
5 , R
4 is NH
2 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 95 Compounds of formula I.1* in which R
1 is CH
2 -cC
3 H
5 , R
4 is NH
2 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 96 Compounds of formula I.1* in which R
1 is CH
2 -cC
5 H
9 , R
4 is NH
2 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 97 Compounds of formula I.1* in which R
1 is CH
2 CH=CH
2 , R
4 is NH
2 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 98 Compounds of formula I.1* in which R
1 is CH
2 C≡CH, R
4 is NH
2 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 99 Compounds of formula I.1* in which R
1 is H, R
4 is NHCH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 100 Compounds of formula I.1* in which R
1 is CH
3 , R
4 is NHCH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 101 Compounds of formula I.1* in which R
1 is C
2 H
5 , R
4 is NHCH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 102 Compounds of formula I.1* in which R
1 is CH
2 -cC
3 H
5 , R
4 is NHCH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 103 Compounds of formula I.1* in which R
1 is CH
2 -cC
5 H
9 , R
4 is NHCH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 104 Compounds of formula I.1* in which R
1 is CH
2 CH=CH
2 , R
4 is NHCH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 105 Compounds of formula I.1* in which R
1 is CH
2 C≡CH, R
4 is NHCH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 106 Compounds of formula I.1* in which R
1 is H, R
4 is N(CH
3 )C
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 107 Compounds of formula I.1* in which R
1 is CH
3 , R
4 is N(CH
3 )C
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 108 Compounds of formula I.1* in which R
1 is C
2 H
5 , R
4 is N(CH
3 )C
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 109 Compounds of formula I.1* in which R
1 is CH
2 -cC
3 H
5 , R
4 is N(CH
3 )C
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 110 Compounds of formula I.1* in which R
1 is CH
2 -cC
5 H
9 , R
4 is N(CH
3 )C
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 111 Compounds of formula I.1* in which R
1 is CH
2 CH=CH
2 , R
4 is N(CH
3 )C
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 112 Compounds of formula I.1* in which R
1 is CH
2 C≡CH, R
4 is N(CH
3 )C
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 113 Compounds of formula I.1* in which R
1 is H, R
4 is NHCH
2 CN, and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 114 Compounds of formula I.1* in which R
1 is CH
3 , R
4 is NHCH
2 CN, and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 115 Compounds of formula I.1* in which R
1 is C
2 H
5 , R
4 is NHCH
2 CN, and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 116 Compounds of formula I.1* in which R
1 is CH
2 -cC
3 H
5 , R
4 is NHCH
2 CN, and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 117 Compounds of formula I.1* in which R
1 is CH
2 -cC
5 H
9 , R
4 is NHCH
2 CN, and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 118 Compounds of formula I.1* in which R
1 is CH
2 CH=CH
2 , R
4 is NHCH
2 CN, and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 119 Compounds of formula I.1* in which R
1 is CH
2 C≡CH, R
4 is NHCH
2 CN, and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 120 Compounds of formula I.1* in which R
1 is H, R
4 is 4,5-dihydrooxazol-2-yl, and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 121 Compounds of formula I.1* in which R
1 is CH
3 , R
4 is 4,5-dihydrooxazol-2-yl, and the combina- tion of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 122 Compounds of formula I.1* in which R
1 is C
2 H
5 , R
4 is 4,5-dihydrooxazol-2-yl, and the combina- tion of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 123 Compounds of formula I.1* in which R
1 is CH
2 -cC
3 H
5 , R
4 is 4,5-dihydrooxazol-2-yl, and the com- bination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 124 Compounds of formula I.1* in which R
1 is CH
2 -cC
5 H
9 , R
4 is 4,5-dihydrooxazol-2-yl, and the com- bination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 125 Compounds of formula I.1* in which R
1 is CH
2 CH=CH
2 , R
4 is 4,5-dihydrooxazol-2-yl, and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 126 Compounds of formula I.1* in which R
1 is CH
2 C≡CH, R
4 is 4,5-dihydrooxazol-2-yl, and the com- bination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 127 Compounds of formula I.2* in which R
1 is H, R
4 is H, and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 128 Compounds of formula I.2* in which R
1 is CH
3 , R
4 is H, and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 129 Compounds of formula I.2* in which R
1 is C
2 H
5 , R
4 is H, and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 130 Compounds of formula I.2* in which R
1 is CH
2 -cC
3 H
5 , R
4 is H, and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 131 Compounds of formula I.2* in which R
1 is CH
2 -cC
5 H
9 , R
4 is H, and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 132 Compounds of formula I.2* in which R
1 is CH
2 CH=CH
2 , R
4 is H, and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 133 Compounds of formula I.2* in which R
1 is CH
2 C≡CH, R
4 is H, and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 134 Compounds of formula I.2* in which R
1 is H, R
4 is CN, and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 135 Compounds of formula I.2* in which R
1 is CH
3 , R
4 is CN, and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 136 Compounds of formula I.2* in which R
1 is C
2 H
5 , R
4 is CN, and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 137 Compounds of formula I.2* in which R
1 is CH
2 -cC
3 H
5 , R
4 is CN, and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 138 Compounds of formula I.2* in which R
1 is CH
2 -cC
5 H
9 , R
4 is CN, and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 139 Compounds of formula I.2* in which R
1 is CH
2 CH=CH
2 , R
4 is CN, and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 140 Compounds of formula I.2* in which R
1 is CH
2 C≡CH, R
4 is CN, and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 141 Compounds of formula I.2* in which R
1 is H, R
4 is CH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 142 Compounds of formula I.2* in which R
1 is CH
3 , R
4 is CH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 143 Compounds of formula I.2* in which R
1 is C
2 H
5 , R
4 is CH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 144 Compounds of formula I.2* in which R
1 is CH
2 -cC
3 H
5 , R
4 is CH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 145 Compounds of formula I.2* in which R
1 is CH
2 -cC
5 H
9 , R
4 is CH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 146 Compounds of formula I.2* in which R
1 is CH
2 CH=CH
2 , R
4 is CH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 147 Compounds of formula I.2* in which R
1 is CH
2 C≡CH, R
4 is CH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 148 Compounds of formula I.2* in which R
1 is H, R
4 is C
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 149 Compounds of formula I.2* in which R
1 is CH
3 , R
4 is C
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 150 Compounds of formula I.2* in which R
1 is C
2 H
5 , R
4 is C
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 151 Compounds of formula I.2* in which R
1 is CH
2 -cC
3 H
5 , R
4 is C
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 152 Compounds of formula I.2* in which R
1 is CH
2 -cC
5 H
9 , R
4 is C
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 153 Compounds of formula I.2* in which R
1 is CH
2 CH=CH
2 , R
4 is C
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 154 Compounds of formula I.2* in which R
1 is CH
2 C≡CH, R
4 is C
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 155 Compounds of formula I.2* in which R
1 is H, R
4 is CH
2 CH
2 CH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 156 Compounds of formula I.2* in which R
1 is CH
3 , R
4 is CH
2 CH
2 CH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 157 Compounds of formula I.2* in which R
1 is C
2 H
5 , R
4 is CH
2 CH
2 CH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 158 Compounds of formula I.2* in which R
1 is CH
2 -cC
3 H
5 , R
4 is CH
2 CH
2 CH
3 , and the combination of X and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 159 Compounds of formula I.2* in which R
1 is CH
2 -cC
5 H
9 , R
4 is CH
2 CH
2 CH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 160 Compounds of formula I.2* in which R
1 is CH
2 CH=CH
2 , R
4 is CH
2 CH
2 CH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 161 Compounds of formula I.2* in which R
1 is CH
2 C≡CH, R
4 is CH
2 CH
2 CH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 162 Compounds of formula I.2* in which R
1 is H, R
4 is CH(CH
3 )
2 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 163 Compounds of formula I.2* in which R
1 is CH
3 , R
4 is CH(CH
3 )
2 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 164 Compounds of formula I.2* in which R
1 is C
2 H
5 , R
4 is CH(CH
3 )
2 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 165 Compounds of formula I.2* in which R
1 is CH
2 -cC
3 H
5 , R
4 is CH(CH
3 )
2 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 166 Compounds of formula I.2* in which R
1 is CH
2 -cC
5 H
9 , R
4 is CH(CH
3 )
2 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 167 Compounds of formula I.2* in which R
1 is CH
2 CH=CH
2 , R
4 is CH(CH
3 )
2 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 168 Compounds of formula I.2* in which R
1 is CH
2 C≡CH, R
4 is CH(CH
3 )
2 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 169 Compounds of formula I.2* in which R
1 is H, R
4 is C(=O)NH
2 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 170 Compounds of formula I.2* in which R
1 is CH
3 , R
4 is C(=O)NH
2 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 171 Compounds of formula I.2* in which R
1 is C
2 H
5 , R
4 is C(=O)NH
2 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 172 Compounds of formula I.2* in which R
1 is CH
2 -cC
3 H
5 , R
4 is C(=O)NH
2 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 173 Compounds of formula I.2* in which R
1 is CH
2 -cC
5 H
9 , R
4 is C(=O)NH
2 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 174 Compounds of formula I.2* in which R
1 is CH
2 CH=CH
2 , R
4 is C(=O)NH
2 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 175 Compounds of formula I.2* in which R
1 is CH
2 C≡CH, R
4 is C(=O)NH
2 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 176 Compounds of formula I.2* in which R
1 is H, R
4 is C(=O)NHCH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 177 Compounds of formula I.2* in which R
1 is CH
3 , R
4 is C(=O)NHCH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 178 Compounds of formula I.2* in which R
1 is C
2 H
5 , R
4 is C(=O)NHCH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 179 Compounds of formula I.2* in which R
1 is CH
2 -cC
3 H
5 , R
4 is C(=O)NHCH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 180 Compounds of formula I.2* in which R
1 is CH
2 -cC
5 H
9 , R
4 is C(=O)NHCH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 181 Compounds of formula I.2* in which R
1 is CH
2 CH=CH
2 , R
4 is C(=O)NHCH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 182 Compounds of formula I.2* in which R
1 is CH
2 C≡CH, R
4 is C(=O)NHCH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 183 Compounds of formula I.2* in which R
1 is H, R
4 is C(=O)NHC
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 184 Compounds of formula I.2* in which R
1 is CH
3 , R
4 is C(=O)NHC
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 185 Compounds of formula I.2* in which R
1 is C
2 H
5 , R
4 is C(=O)NHC
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 186 Compounds of formula I.2* in which R
1 is CH
2 -cC
3 H
5 , R
4 is C(=O)NHC
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 187 Compounds of formula I.2* in which R
1 is CH
2 -cC
5 H
9 , R
4 is C(=O)NHC
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 188 Compounds of formula I.2* in which R
1 is CH
2 CH=CH
2 , R
4 is C(=O)NHC
2 H
5 , and the combina- tion of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 189 Compounds of formula I.2* in which R
1 is CH
2 C≡CH, R
4 is C(=O)NHC
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 190 Compounds of formula I.2* in which R
1 is H, R
4 is C(=O)N(CH
3 )
2 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 191 Compounds of formula I.2* in which R
1 is CH
3 , R
4 is C(=O)N(CH
3 )
2 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 192 Compounds of formula I.2* in which R
1 is C
2 H
5 , R
4 is C(=O)N(CH
3 )
2 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 193 Compounds of formula I.2* in which R
1 is CH
2 -cC
3 H
5 , R
4 is C(=O)N(CH
3 )
2 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 194 Compounds of formula I.2* in which R
1 is CH
2 -cC
5 H
9 , R
4 is C(=O)N(CH
3 )
2 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 195 Compounds of formula I.2* in which R
1 is CH
2 CH=CH
2 , R
4 is C(=O)N(CH
3 )
2 , and the combina- tion of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 196 Compounds of formula I.2* in which R
1 is CH
2 C≡CH, R
4 is C(=O)N(CH
3 )
2 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 197 Compounds of formula I.2* in which R
1 is H, R
4 is C(=O)N(CH
3 )C
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 198 Compounds of formula I.2* in which R
1 is CH
3 , R
4 is C(=O)N(CH
3 )C
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 199 Compounds of formula I.2* in which R
1 is C
2 H
5 , R
4 is C(=O)N(CH
3 )C
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 200 Compounds of formula I.2* in which R
1 is CH
2 -cC
3 H
5 , R
4 is C(=O)N(CH
3 )C
2 H
5 , and the combina- tion of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 201 Compounds of formula I.2* in which R
1 is CH
2 -cC
5 H
9 , R
4 is C(=O)N(CH
3 )C
2 H
5 , and the combina- tion of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 202 Compounds of formula I.2* in which R
1 is CH
2 CH=CH
2 , R
4 is C(=O)N(CH
3 )C
2 H
5 , and the combi- nation of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 203 Compounds of formula I.2* in which R
1 is CH
2 C≡CH, R
4 is C(=O)N(CH
3 )C
2 H
5 , and the combina- tion of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 204 Compounds of formula I.2* in which R
1 is H, R
4 is C(=O)OCH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 205 Compounds of formula I.2* in which R
1 is CH
3 , R
4 is C(=O)OCH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 206 Compounds of formula I.2* in which R
1 is C
2 H
5 , R
4 is C(=O)OCH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 207 Compounds of formula I.2* in which R
1 is CH
2 -cC
3 H
5 , R
4 is C(=O)OCH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 208 Compounds of formula I.2* in which R
1 is CH
2 -cC
5 H
9 , R
4 is C(=O)OCH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 209 Compounds of formula I.2* in which R
1 is CH
2 CH=CH
2 , R
4 is C(=O)OCH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 210 Compounds of formula I.2* in which R
1 is CH
2 C≡CH, R
4 is C(=O)OCH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 211 Compounds of formula I.2* in which R
1 is H, R
4 is C(=O)OC
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 212 Compounds of formula I.2* in which R
1 is CH
3 , R
4 is C(=O)OC
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 213 Compounds of formula I.2* in which R
1 is C
2 H
5 , R
4 is C(=O)OC
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 214 Compounds of formula I.2* in which R
1 is CH
2 -cC
3 H
5 , R
4 is C(=O)OC
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 215 Compounds of formula I.2* in which R
1 is CH
2 -cC
5 H
9 , R
4 is C(=O)OC
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 216 Compounds of formula I.2* in which R
1 is CH
2 CH=CH
2 , R
4 is C(=O)OC
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 217 Compounds of formula I.2* in which R
1 is CH
2 C≡CH, R
4 is C(=O)OC
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 218 Compounds of formula I.2* in which R
1 is H, R
4 is NH
2 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 219 Compounds of formula I.2* in which R
1 is CH
3 , R
4 is NH
2 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 220 Compounds of formula I.2* in which R
1 is C
2 H
5 , R
4 is NH
2 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 221 Compounds of formula I.2* in which R
1 is CH
2 -cC
3 H
5 , R
4 is NH
2 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 222 Compounds of formula I.2* in which R
1 is CH
2 -cC
5 H
9 , R
4 is NH
2 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 223 Compounds of formula I.2* in which R
1 is CH
2 CH=CH
2 , R
4 is NH
2 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 224 Compounds of formula I.2* in which R
1 is CH
2 C≡CH, R
4 is NH
2 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 225 Compounds of formula I.2* in which R
1 is H, R
4 is NHCH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 226 Compounds of formula I.2* in which R
1 is CH
3 , R
4 is NHCH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 227 Compounds of formula I.2* in which R
1 is C
2 H
5 , R
4 is NHCH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 228 Compounds of formula I.2* in which R
1 is CH
2 -cC
3 H
5 , R
4 is NHCH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 229 Compounds of formula I.2* in which R
1 is CH
2 -cC
5 H
9 , R
4 is NHCH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 230 Compounds of formula I.2* in which R
1 is CH
2 CH=CH
2 , R
4 is NHCH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 231 Compounds of formula I.2* in which R
1 is CH
2 C≡CH, R
4 is NHCH
3 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 232 Compounds of formula I.2* in which R
1 is H, R
4 is N(CH
3 )C
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 233 Compounds of formula I.2* in which R
1 is CH
3 , R
4 is N(CH
3 )C
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 234 Compounds of formula I.2* in which R
1 is C
2 H
5 , R
4 is N(CH
3 )C
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 235 Compounds of formula I.2* in which R
1 is CH
2 -cC
3 H
5 , R
4 is N(CH
3 )C
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 236 Compounds of formula I.2* in which R
1 is CH
2 -cC
5 H
9 , R
4 is N(CH
3 )C
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 237 Compounds of formula I.2* in which R
1 is CH
2 CH=CH
2 , R
4 is N(CH
3 )C
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 238 Compounds of formula I.2* in which R
1 is CH
2 C≡CH, R
4 is N(CH
3 )C
2 H
5 , and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 239 Compounds of formula I.2* in which R
1 is H, R
4 is NHCH
2 CN, and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 240 Compounds of formula I.2* in which R
1 is CH
3 , R
4 is NHCH
2 CN, and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 241 Compounds of formula I.2* in which R
1 is C
2 H
5 , R
4 is NHCH
2 CN, and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 242 Compounds of formula I.2* in which R
1 is CH
2 -cC
3 H
5 , R
4 is NHCH
2 CN, and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 243 Compounds of formula I.1* in which R
1 is CH
2 -cC
5 H
9 , R
4 is NHCH
2 CN, and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 244 Compounds of formula I.2* in which R
1 is CH
2 CH=CH
2 , R
4 is NHCH
2 CN, and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 245 Compounds of formula I.2* in which R
1 is CH
2 C≡CH, R
4 is NHCH
2 CN, and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 246 Compounds of formula I.2* in which R
1 is H, R
4 is 4,5-dihydrooxazol-2-yl, and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 247 Compounds of formula I.2* in which R
1 is CH
3 , R
4 is 4,5-dihydrooxazol-2-yl, and the combina- tion of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 248 Compounds of formula I.2* in which R
1 is C
2 H
5 , R
4 is 4,5-dihydrooxazol-2-yl, and the combina- tion of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 249 Compounds of formula I.2* in which R
1 is CH
2 -cC
3 H
5 , R
4 is 4,5-dihydrooxazol-2-yl, and the com- bination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 250 Compounds of formula I.2* in which R
1 is CH
2 -cC
5 H
9 , R
4 is 4,5-dihydrooxazol-2-yl, and the com- bination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 251 Compounds of formula I.2* in which R
1 is CH
2 CH=CH
2 , R
4 is 4,5-dihydrooxazol-2-yl, and the combination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table 252 Compounds of formula I.2* in which R
1 is CH
2 C≡CH, R
4 is 4,5-dihydrooxazol-2-yl, and the com- bination of NR
5 and (R
3 )
n for a compound corresponds in each case to one row of Table A Table A
The term “compound(s) of the invention” refers to compound(s) of formula I, or “compound(s) I”, and includes their salts, tautomers, stereoisomers, and N-oxides. The invention also relates to agrochemical compositions comprising an auxiliary and at least one compound I. An agrochemical composition comprises a pesticidally effective amount of a compound I. An agrochemical composition comprises a pesticidally effective amount of a compound I. The compounds I can be converted into customary types of agro-chemical compositions, e.g. solutions, emulsions, suspensions, dusts, powders, pastes, granules, pressings, capsules, and mixtures thereof. Examples for composition types are suspensions (e.g. SC, OD, FS), emulsifia- ble concentrates (e.g. EC), emulsions (e.g. EW, EO, ES, ME), capsules (e.g. CS, ZC), pastes, pastilles, wettable powders or dusts (e.g. WP, SP, WS, DP, DS), pressings (e.g. BR, TB, DT), granules (e.g. WG, SG, GR, FG, GG, MG), insecticidal articles (e.g. LN), as well as gel formula- tions for the treatment of plant propagation materials e.g. seeds (e.g. GF). These and further compositions types are defined in the “Catalogue of pesticide formulation types and interna- tional coding system”, Technical Monograph No.2, 6th Ed. May 2008, CropLife International. Suitable auxiliaries are solvents, liquid carriers, solid carriers or fillers, surfactants, disper- sants, emulsifiers, wetters, adjuvants, solubilizers, penetration enhancers, protective colloids, adhesion agents, thickeners, humectants, repellents, attractants, feeding stimulants, compatibil- izers, bactericides, anti-freezing agents, anti-foaming agents, colorants, tackifiers and binders. Suitable solvents and liquid carriers are water and organic solvents. Suitable solid carriers or fillers are mineral earths. Suitable surfactants are surface-active compounds, e.g. anionic, cationic, nonionic, and am- photeric surfactants, block polymers, polyelectrolytes. Such surfactants can be used as emulsi- fier, dispersant, solubilizer, wetter, penetration enhancer, protective colloid, or adjuvant. Surfac- tants are listed in McCutcheon’s, Vol.1: Emulsifiers & Detergents, McCutcheon’s Directories, Glen Rock, USA, 2008 (International or North American Ed.). Suitable anionic surfactants are alkali, alkaline earth, or ammonium salts of sulfonates, sulfates, phosphates, carboxylates. Suit- able nonionic surfactants are alkoxylates, N-subsituted fatty acid amides, amine oxides, esters, sugar-based surfactants, polymeric surfactants. Suitable cationic surfactants are quaternary surfactants. The agrochemical compositions generally comprise between 0.01 and 95%, preferably be- tween 0.1 and 90%, and most preferably between 0.5 and 75%, by weight of active substance. The active substances are employed in a purity of from 90% to 100%, preferably from 95% to 100%. Various types of oils, wetters, adjuvants, or fertilizer may be added to the active substances or the compositions comprising them as premix or, if appropriate not until immediately prior to use (tank mix). These agents can be admixed with the compositions according to the invention in a weight ratio of 1:100 to 100:1. The user applies the composition according to the invention usually from a predosage device, a knapsack sprayer, a spray tank, a spray plane, or an irrigation system. Usually, the agrochem- ical composition is made up with water, buffer, and/or further auxiliaries to the desired applica- tion concentration and the ready-to-use spray liquor or the agrochemical composition according to the invention is thus obtained. Usually, 20 to 2000 liters of the ready-to-use spray liquor are applied per hectare of agricultural useful area. The compounds I are suitable for use in protecting crops, plants, plant propagation materials, e.g. seeds, or soil or water, in which the plants are growing, from attack or infestation by animal pests. Therefore, the invention also relates to a plant protection method, which comprises con- tacting crops, plants, plant propagation materials, e.g. seeds, or soil or water, in which the plants are growing, to be protected from attack or infestation by animal pests, with a pesticidally effective amount of a compound I. The compounds I are also suitable for use in combating or controlling animal pests. Therefore, the invention also relates to a method of combating or controlling animal pests, which comprises contacting the animal pests, their habitat, breeding ground, or food supply, or the crops, plants, plant propagation materials, e.g. seeds, or soil, or the area, material or environment in which the animal pests are growing or may grow, with a pesticidally effective amount of a compound I. The compounds I are effective through both contact and ingestion to any and all developmen- tal stages, such as egg, larva, pupa, and adult. The compounds I can be applied as such or in form of compositions comprising them. The application can be carried out both before and after the infestation of the crops, plants, plant propagation materials by the pests. The term "contacting" includes both direct contact (applying the compounds/compositions di- rectly on the animal pest or plant) and indirect contact (applying the compounds/compositions to the locus). The term “animal pest” includes arthropods, gastropods, and nematodes. Preferred animal pests according to the invention are arthropods, preferably insects and arachnids, in particular insects. The term “plant” includes cereals, e.g. durum and other wheat, rye, barley, triticale, oats, rice, or maize (fodder maize and sugar maize / sweet and field corn); beet, e.g. sugar beet, or fodder beet; fruits, e.g. pomes, stone fruits, or soft fruits, e.g. apples, pears, plums, peaches, nectar- ines, almonds, cherries, papayas, strawberries, raspberries, blackberries or gooseberries; legu- minous plants, e.g. beans, lentils, peas, alfalfa, or soybeans; oil plants, e.g. rapeseed (oilseed rape), turnip rape, mustard, olives, sunflowers, coconut, cocoa beans, castor oil plants, oil palms, ground nuts, or soybeans; cucurbits, e.g. squashes, pumpkins, cucumber or melons; fi- ber plants, e.g. cotton, flax, hemp, or jute; citrus fruit, e.g. oranges, lemons, grapefruits or man- darins; vegetables, e.g. eggplant, spinach, lettuce (e.g. iceberg lettuce), chicory, cabbage, as- paragus, cabbages, carrots, onions, garlic, leeks, tomatoes, potatoes, cucurbits or sweet pep- pers; lauraceous plants, e.g. avocados, cinnamon, or camphor; energy and raw material plants, e.g. corn, soybean, rapeseed, sugar cane or oil palm; tobacco; nuts, e.g. walnuts; pistachios; coffee; tea; bananas; vines; hop; sweet leaf (Stevia); natural rubber plants or ornamental and forestry plants, shrubs, broad-leaved trees or evergreens, eucalyptus; turf; lawn; grass. Pre- ferred plants include potatoes, sugar beets, tobacco, wheat, rye, barley, oats, rice, corn, cotton, soybeans, rapeseed, legumes, sunflowers, coffee, or sugar cane; fruits; vines; ornamentals; or vegetables, e.g. cucumbers, tomatoes, beans or squashes. The term “seed” embraces seeds and plant propagules including true seeds, seed pieces, suckers, corms, bulbs, fruit, tubers, grains, cuttings, cut shoots, and means preferably true seeds. "Pesticidally effective amount" means the amount of active ingredient needed to achieve an observable effect on growth, including the effects of necrosis, death, retardation, prevention, and removal, destruction, or otherwise diminishing the occurrence and activity of the target or- ganism. The pesticidally effective amount can vary for the various compounds/compositions used in the invention. A pesticidally effective amount of the compositions will also vary accord- ing to the prevailing conditions e.g. desired pesticidal effect and duration, weather, target spe- cies, locus, mode of application. For use in treating crop plants, e.g. by foliar application, the rate of application of the active in- gredients of this invention may be in the range of 0.0001 g to 4000 g per hectare, e.g. from 1 g to 2 kg per hectare or from 1 g to 750 g per hectare, desirably from 1 g to 100 g per hectare. The compounds I are also suitable for use against non-crop insect pests. For use against said non-crop pests, compounds I can be used as bait composition, gel, general insect spray, aero- sol, as ultra-low volume application and bed net (impregnated or surface applied). The term “non-crop insect pest” refers to pests, which are particularly relevant for non-crop tar- gets, e.g. ants, termites, wasps, flies, ticks, mosquitoes, bed bugs, crickets, or cockroaches, such as: Aedes aegypti, Musca domestica, Tribolium spp.; termites such as Reticulitermes flavipes, Coptotermes formosanus; roaches such as Blatella germanica, Periplaneta Americana; ants such as Solenopsis invicta, Linepithema humile, and Camponotus pennsylvanicus. The bait can be a liquid, a solid or a semisolid preparation (e.g. a gel). For use in bait composi- tions, the typical content of active ingredient is from 0.001 wt% to 15 wt%, desirably from 0.001 wt% to 5 wt% of active compound. The compounds I and its compositions can be used for protecting wooden materials such as trees, board fences, sleepers, frames, artistic artifacts, etc. and buildings, but also construction materials, furniture, leathers, fibers, vinyl articles, electric wires and cables etc. from ants, ter- mites and/or wood or textile destroying beetles, and for controlling ants and termites from doing harm to crops or human beings (e.g. when the pests invade into houses and public facilities or nest in yards, orchards or parks). Customary application rates in the protection of materials are, e.g., from 0.001 g to 2000 g or from 0.01 g to 1000 g of active compound per m 2 treated material, desirably from 0.1 g to 50 g per m 2 . Insecticidal compositions for use in the impregnation of materials typically contain from 0.001 to 95 wt%, preferably from 0.1 to 45 wt%, and more preferably from 1 to 25 wt% of at least one repellent and/or insecticide. The compounds of the invention are especially suitable for efficiently combating animal pests e.g. arthropods, and nematodes including: insects from the sub-order of Auchenorrhyncha, e.g. Amrasca biguttula, Empoasca spp., Ne- photettix virescens, Sogatella furcifera, Mahanarva spp., Laodelphax striatellus, Nilaparvata lugens, Diaphorina citri; Lepidoptera, e.g. Helicoverpa spp., Heliothis virescens, Lobesia botrana, Ostrinia nubilalis, Plu-tella xylostella, Pseudoplusia includens, Scirpophaga incertulas, Spodoptera spp., Trichop- lusia ni, Tuta absoluta, Cnaphalocrocis medialis, Cydia pomonella, Chilo suppressalis, Anticar- sia gemmatalis, Agrotis ipsilon, Chrysodeixis includens; True bugs, e.g. Lygus spp., Stink bugs such as Euschistus spp., Halyomorpha halys, Nezara viridula, Piezodorus guildinii, Dichelops furcatus; Thrips, e.g. Frankliniella spp., Thrips spp., Dichromothrips corbettii; Aphids, e.g. Acyrthosiphon pisum, Aphis spp., Myzus persicae, Rhopalosiphum spp., Schi- zaphis graminum, Megoura viciae; Whiteflies, e.g. Trialeurodes vaporariorum, Bemisia spp.; Coleoptera, e.g. Phyllotreta spp., Melanotus spp., Meligethes aeneus, Leptinotarsa decimline- ata, Ceutorhynchus spp., Diabrotica spp., Anthonomus grandis, Atomaria linearia, Agriotes spp., Epilachna spp.; Flies, e.g. Delia spp., Ceratitis capitate, Bactrocera spp., Liriomyza spp.; Mosquitoes (Diptera), e.g. Aedes aegypti, A. albopictus, A. vexans, Anastrepha ludens, Anopheles maculipennis, A. crucians, A. albimanus, A. gambiae, A. freeborni, A. leucosphyrus, A. minimus, A. quadrimaculatus; Coccoidea, e.g. Aonidiella aurantia, Ferrisia virgate; Anthropods of class Arachnida (Mites), e.g. Penthaleus major, Tetranychus spp.; Nematodes, e.g. Heterodera glycines, Meloidogyne sp., Pratylenchus spp., Caenorhabditis el- egans. The compounds I are suitable for use in treating or protecting animals against infestation or infection by parasites. Therefore, the invention also relates to the use of a compound of the in- vention for the manufacture of a medicament for the treatment or protection of animals against infestation or infection by parasites. Furthermore, the invention relates to a method of treating or protecting animals against infestation and infection by parasites, which comprises orally, topi- cally or parenterally administering or applying to the animals a parasiticidally effective amount of a compound I. The invention also relates to the non-therapeutic use of compounds of the invention for treat- ing or protecting animals against infestation and infection by parasites. Moreover, the invention relates to a non-therapeutic method of treating or protecting animals against infestation and in- fection by parasites, which comprises applying to a locus a parasiticidally effective amount of a compound I. The compounds of the invention are further suitable for use in combating or controlling para- sites in and on animals. Furthermore, the invention relates to a method of combating or control- ling parasites in and on animals, which comprises contacting the parasites with a parasitically effective amount of a compound I. The invention also relates to the non-therapeutic use of compounds I for controlling or combat- ing parasites. Moreover, the invention relates to a non-therapeutic method of combating or con- trolling parasites, which comprises applying to a locus a parasiticidally effective amount of a compound I. The compounds I can be effective through both contact (via soil, glass, wall, bed net, carpet, blankets, or animal parts) and ingestion (e.g. baits). Furthermore, the compounds I can be ap- plied to any and all developmental stages. The compounds I can be applied as such or in form of compositions comprising them. The term "locus" means the habitat, food supply, breeding ground, area, material or environ- ment in which a parasite is growing or may grow outside of the animal. As used herein, the term “parasites” includes endo- and ectoparasites. In some embodiments of the invention, endoparasites can be preferred. In other embodiments, ectoparasites can be preferred. Infestations in warm-blooded animals and fish include lice, biting lice, ticks, nasal bots, keds, biting flies, muscoid flies, flies, myiasitic fly larvae, chiggers, gnats, mosquitoes and fleas. The compounds of the invention are especially useful for combating the following parasites: Cimex lectularius, Rhipicephalus sanguineus, and Ctenocephalides felis. As used herein, the term “animal” includes warm-blooded animals (including humans) and fish. Preferred are mammals, such as cattle, sheep, swine, camels, deer, horses, pigs, poultry, rab- bits, goats, dogs and cats, water buffalo, donkeys, fallow deer and reindeer, and also in furbear- ing animals such as mink, chinchilla and raccoon, birds such as hens, geese, turkeys and ducks and fish such as fresh- and salt-water fish such as trout, carp and eels. Particularly preferred are domestic animals, such as dogs or cats. The compounds I may be applied in total amounts of 0.5 mg/kg to 100 mg/kg per day, prefera- bly 1 mg/kg to 50 mg/kg per day. For oral administration to warm-blooded animals, the compounds I may be formulated as ani- mal feeds, animal feed premixes, animal feed concentrates, pills, solutions, pastes, suspen- sions, drenches, gels, tablets, boluses and capsules. For oral administration, the dosage form chosen should provide the animal with 0.01 mg/kg to 100 mg/kg of animal body weight per day of the compounds I, preferably with 0.5 mg/kg to 100 mg/kg of animal body weight per day. Alternatively, the compounds I may be administered to animals parenterally, e.g., by intrarumi- nal, intramuscular, intravenous or subcutaneous injection. The compounds I may be dispersed or dissolved in a physiologically acceptable carrier for subcutaneous injection. Alternatively, the compounds I may be formulated into an implant for subcutaneous administration. In addition, the compounds I may be transdermally administered to animals. For parenteral administration, the dosage form chosen should provide the animal with 0.01 mg/kg to 100 mg/kg of animal body weight per day of the compounds I. The compounds I may also be applied topically to the animals in the form of dips, dusts, pow- ders, collars, medallions, sprays, shampoos, spot-on and pour-on formulations and in ointments or oil-in-water or water-in-oil emulsions. For topical application, dips and sprays usually contain 0.5 ppm to 5,000 ppm and preferably 1 ppm to 3,000 ppm of the compounds I. In addition, the compounds I may be formulated as ear tags for animals, particularly quadrupeds e.g. cattle and sheep. Oral solutions are administered directly. Solutions for use on the skin are trickled on, spread on, rubbed in, sprinkled on or sprayed on. Gels are applied to or spread on the skin or introduced into body cavities. Pour-on formulations are poured or sprayed onto limited areas of the skin, the active com- pound penetrating the skin and acting systemically. Pour-on formulations are prepared by dis- solving, suspending, or emulsifying the active compound in suitable skin-compatible solvents or solvent mixtures. Emulsions can be administered orally, dermally or as injections. Suspensions can be administered orally or topically/dermally. Semi-solid preparations can be administered orally or topically/dermally. For the production of solid preparations, the active compound is mixed with suitable excipi- ents, if appropriate with addition of auxiliaries, and brought into the desired form. The compositions which can be used in the invention can comprise generally from about 0.001 to 95% of the compound I. Ready-to-use preparations contain the compounds acting against parasites, preferably ecto- parasites, in concentrations of 10 ppm to 80% by weight, preferably from 0.1 to 65% by weight, more preferably from 1 to 50% by weight, most preferably from 5 to 40% by weight. Preparations which are diluted before use contain the compounds acting against ectoparasites in concentrations of 0.5 to 90% by weight, preferably of 1 to 50% by weight. Furthermore, the preparations comprise the compounds of formula I against endoparasites in concentrations of 10 ppm to 2% by weight, preferably of 0.05 to 0.9% by weight, very particu- larly preferably of 0.005 to 0.25% by weight. Solid formulations which release compounds of the invention may be applied in total amounts of 10 mg/kg to 300 mg/kg, preferably 20 mg/kg to 200 mg/kg, most preferably 25 mg/kg to 160 mg/kg body weight of the treated animal in the course of three weeks. A. Preparation examples The compounds were characterized by melting point determination, by NMR spectroscopy or by the mass-to-charge ratio ([m/z]) and retention time (RT; [min]), as determined by mass spec- trometry (MS) coupled with HPLC analysis (HPLC-MS = high performance liquid chromatog- raphy-coupled mass spectrometry) or LC analysis (LC-MS = liquid chromatography-coupled mass spectrometry). Method A: HPLC: Shimadzu Nexera UHPLC + Shimadzu LCMS-2020, ESI; Column: Phenom- enex Kinetex 1.7µm XB-C18100A, 2.1x50mm; Mobile phase: A: water + 0.1% TFA; B: ACN; Temperature: 60°C; Gradient: 5% B to 100% B in 1.5 min; 100% B 0.25 min; Flow: 0.8 mL/min to 1.0 mL/min in 1.51 min; MS: ESI positive; Mass range (m/z): 100–700. Method B: LC: Shimadzu LC-30AD, ESI; Column: Kinetex EVO C18.5µm 2.1x30mm; Mobile phase: A: water + 0.04% TFA; B: ACN + 0.02% TFA; Temperature: 40°C; Gradient: 5% B to 100% B in 2.5 min; 100% B to 5% B in 0.02min; 5% B for 0.5min; Flow: 0.8mL/min; MS: ESI positive; Mass range: 100–2000. Example 1: preparation of N-[1-[3-[N'-hydroxycarbamimidoyl]pyrazin-2-yl]ethyl]-3,5-bis
(trifluo- romethyl)benzamide (I-3) Step 1: preparation of 1-(3-chloropyrazin-2-yl)ethanamine To a mixture of 1-(3-chloropyrazin-2-yl)ethanone (10g, 63.8mmol) and NH 4 OAc (60.4g, 957.8mmol) in EtOH (500mL) were added NaBH 3 CN (12.04g, 191.4mmol) and NH 3 /MeOH (150mL, 7N) at 30°C. The mixture was stirred at 50°C until completion was determined by LCMS (16h). The reaction mixture was quenched with H 2 O (100 mL) and concentrated to re- move MeOH and EtOH.6N aq. NaOH was added to adjust the pH of the residue to 11 and the resulting mixture was extracted with EtOAc (3x100mL). The combined organic layers were dried over Na 2 SO 4 , filtered, and concentrated. The crude product was purified by preparative HPLC (NH 4 HCO 3 ) to deliver 1-(3-chloropyrazin-2-yl)ethanamine (10 g, 50% yield) as a white solid. 1H-NMR (400MHz, DMSO-d 6 ): δ = 8.70 (d, J = 2.4Hz, 1H), 8.47 (d, J = 2.5Hz, 1H), 4.50 (q, J = 6.7Hz, 1H), 1.37 (d, J = 6.8Hz, 3H). Step 2: preparation of N-[1-(3-chloropyrazin-2-yl)ethyl]-3,5-bis(trifluoromethyl)be
nzamide To a mixture of 3,5-bis(trifluoromethyl)benzoic acid (19.65g, 76.14mmol) and chloro- N,N,N´,N´-tetramethylformamidinium hexafluorophosphate (21.36g, 76.14mmol) in MeCN (200mL) were added N-methylimidazole (16.7g, 203.2mmol) and 1-(3-chloropyrazin-2-yl)eth- anamine (8.0g, 50.8mmol) at 30°C. The reaction mixture was stirred until completion was deter- mined by TLC (PE: EtOAc=3:1, Rf =0.45; 16h). The reaction mixture was quenched with H 2 O (50 mL) and extracted with EtOAc (3x100mL). The combined organic layers were dried over Na 2 SO 4 , filtered, and concentrated. The crude product was purified by chromatographic column on silica gel (eluent: 12% EtOAc in PE) to deliver N-[1-(3-chloropyrazin-2-yl)ethyl]-3,5-bis(trifluo- romethyl)benzamide (13g, 43% yield) as a yellow solid. 1H NMR (400 MHz, DMSO-d 6 ): δ = 9.53 (d, J = 6.8 Hz, 1H), 8.65 (d, J = 2.5Hz, 1H), 8.55 (s, 2H), 8.46 (d, J = 2.5Hz, 1H), 8.33 (s, 1H), 5.53 (dq, J = 6.8Hz, J = 6.9Hz, 1H), 1.56 (d, J = 6.9 Hz, 3H). Step 3: preparation of N-[1-(3-cyanopyrazin 2 yl)ethyl] 3,5 bis(trifluoromethyl)benzamide To a solution of N-[1-(3-chloropyrazin-2-yl)ethyl]-3,5-bis(trifluoromethyl)be
nzamide (1.0g, 2.51mmol) in DMF (10mL) were added Zn(CN) 2 (330mg, 2.76mmol) and Pd(PPh 3 ) 4 (350mg, 0.30mmol) at 20°C, and the resulting mixture was purged with N 2 for 3 min. The vial was sealed and subjected to microwave irradiation (Biotage Smith Synthesis, 130°C, 10min). Completion was determined by TLC (PE: EtOAc=3:1, Rf =0.4). The reaction mixture was filtered through a celite pad, the filter cake was washed with EtOAc (50mL), and the filtrate was concentrated. The crude product was purified by chromatographic column on silica gel (eluent: 17% EtOAc in PE) to deliver N-[1-(3-cyanopyrazin-2-yl)ethyl]-3,5-bis(trifluoromethyl)ben
zamide (2.6g, 45% yield) as a yellow solid. 1H-NMR (400MHz, CDCl 3 ): δ 8.77 (d, J = 2.3Hz, 1H), 8.70 (d, J = 2.4Hz, 1H), 8.28 (s, 2H), 8.04 (s, 1H), 7.37–7.28 (m, 1H), 5.84–5.73 (m, 1H), 1.74 (d, J = 6.8Hz, 3H). Step 4: preparation of N-[1-[3-[N'-hydroxycarbamimidoyl]pyrazin-2-yl]ethyl]-3,5-bis
(trifluorome- thyl)benzamide (I-3) To a solution of N-[1-(3-cyanopyrazin-2-yl)ethyl]-3,5-bis(trifluoromethyl)ben
zamide (1.1g, 2.8mmol) in EtOH (20mL) were added HONH 2 •HCl (238 mg, 3.36 mmol) and triethylamine (575 mg, 5.6mmol) at 30°C. The resulting mixture was stirred at 80°C for 2.5h, until completion was determined by TLC (PE: EtOAc=3:1, Rf =0.3). The reaction mixture was quenched with H 2 O (10mL) and extracted with EtOAc (3x20mL). The combined organic layers were dried over Na 2 SO 4 , filtered, and concentrated. The crude product was purified by chromatographic column on silica gel (25% EtOAc in PE) to deliver N-[1-[3-[N'-hydroxycarbamimidoyl]pyrazin-2-yl]ethyl]- 3,5-bis(trifluoromethyl)benzamide (I-3, 600mg, 51% yield) as a white solid. 1H-NMR (400MHz, DMSO-d 6 ) δ = 10.21 (s, 1H), 9.42 (d, J = 7.2Hz, 1H), 8.62 (d, J = 2.4Hz, 1H), 8.57 (d, J = 2.3Hz, 1H), 8.54 (s, 2H), 8.30 (s, 1H), 6.12 (dq, J = 6.8Hz, J = 7.2Hz, 1H), 5.96 (s, 2H), 1.54 (d, J = 6.8Hz, 3H). LCMS: 421.1 (desired); 422.0 (observed). Example 2: preparation of N-[1-[3-[N'-methoxycarbamimidoyl]pyrazin-2-yl]ethyl]-3,5-bis
(trifluo- romethyl)benzamide (I-5) To a solution of N-[1-[3-[N'-hydroxycarbamimidoyl]pyrazin-2-yl]ethyl]-3,5-bis
(trifluorome- thyl)benzamide (I-3, 600mg, 1.42mmol) in MeOH (4.8mL) was added a solution of KOH (72mg, 1.28mmol) in H 2 O (1.2mL). Next, MeI (182mg, 1.28mmol) was added dropwise at 30°C. The re- action was stirred for 16h, until completion was determined by TLC (PE: EtOAc=3:1, Rf =0.4). The reaction mixture was quenched with H 2 O (10mL) and the pH of the resulting mixture was adjusted to 7 by addition of 1N aq. HCl. The resulting mixture was extracted with EtOAc (3x30mL). The combined organic layers were dried over Na 2 SO 4 , filtered, and concentrated. The crude product was purified by chromatographic column on silica gel (20% EtOAc in PE) to deliver N-[1-[3-[N'-methoxycarbamimidoyl]pyrazin-2-yl]ethyl]-3,5-bis
(trifluoromethyl)benzamide (I-5, 145mg, 23% yield) as a yellow solid. 1H-NMR (400MHz, DMSO-d 6 ) δ = 9.43 (d, J = 7.0Hz, 1H), 8.65 (d, J = 2.3 Hz, 1H), 8.58 (d, J = 2.3 Hz, 1H), 8.53 (s, 2H), 8.30 (s, 1H), 6.21 (s, 2H), 5.98 (dq, J = 6.8 Hz, J = 7.0 Hz, 1H), 3.80 (s, 3H), 1.58 (d, J = 6.8 Hz, 3H). LCMS: 435.1 (desired); 436.1 (observed). Example 3: preparation of N-[1-[3-[N-methoxy-C-methyl-carbonimidoyl]pyrazin-2-yl]ethyl
]-3,5- bis(trifluoromethyl)benzamide (I-1) Step 1: preparation of N-[1-[3-(1-ethoxyvinyl)pyrazin-2-yl]ethyl]-3,5-bis(trifluoro
methyl)benz- amide To a stirred solution of N-[1-(3-chloropyrazin-2-yl)ethyl]-3,5-bis(trifluoromethyl)be
nzamide (1g, 2.5mmol) in toluene (100mL) were added tributyl(1-ethoxyvinyl)stannane (1.1g, 3.0mmol) and Pd(PPh 3 ) 2 Cl 2 (0.1g, 0.25mmol) at 25°C. The reaction mixture was stirred for 12h at 110°C under an atmosphere of N 2 , at which time completion was determined by TLC (PE: EtOAc =3:1). The reaction mixture was cooled down to 25°C and aq. sat. KF (100mL) was added. The mixture was stirred for 30min, then filtered through a celite pad. The filtrate was extracted with EtOAc (3x40mL). The combined organic layers were washed with brine (60mL), dried over Na 2 SO 4 , and concentrated to furnish N-[1-[3-(1-ethoxyvinyl)pyrazin-2-yl]ethyl]-3,5-bis(trifluoro
methyl)ben- zamide (1.0 g, crude) as a thick yellow oil. The crude product was employed in the next step without further purification. 1H-NMR (400MHz, CDCl 3 ) δ = 8.54 (s, 2H), 8.27 (s, 2H), 8.01 (s, 1H), 7.71 (br d, J=7.5Hz, 1H), 5.86–6.02 (m, 1H), 4.87 (d, J=2.6Hz, 1H), 4.60 (d, J=2.6Hz, 1H), 3.96–4.17 (m, 2H), 1.59 (d, J=6.5Hz, 3H), 1.50 (t, J=7.0Hz, 3H). Step 2: preparation of N-[1-(3-acetylpyrazin-2-yl)ethyl]-3,5-bis(trifluoromethyl)be
nzamide To a stirred solution of N-[1-[3-(1-ethoxyvinyl)pyrazin-2-yl]ethyl]-3,5-bis(trifluoro
methyl)benz- amide (4.3g, 9.93mmol) in THF (60mL) was added aq. HCl (2M, 60mL) dropwise at 0°C. The mixture was stirred for 2h at 20°C, until completion was determined by TLC (PE: EtOAc = 3:1). The reaction mixture was diluted with H 2 O (100mL), extracted with EtOAc (3x50mL). The com- bined organic layers were washed with brine (100mL), dried over Na 2 SO 4 , and concentrated to deliver N-[1-(3-acetylpyrazin-2-yl)ethyl]-3,5-bis(trifluoromethyl)be
nzamide (1.5g, 37% yield) as a white solid. 1H-NMR (400MHz, CDCl 3 ) δ= 8.71 (d, J=2.3Hz, 1H), 8.63 (d, J=2.3Hz, 1H), 8.25 (s, 2H), 8.01 (s, 1H), 7.60 (br d, J=7.8Hz, 1H), 6.03–6.17 (m, 1H), 2.79 (s, 3H), 1.65 (d, J=6.8Hz, 3H). Step 3: preparation of N-[1-[3-[N-methoxy C methyl carbonimidoyl]pyrazin-2-yl]ethyl]-3,5- bis(trifluoromethyl)benzamide (I-1) To a stirred solution of N-[1-(3-acetylpyrazin-2-yl)ethyl]-3,5-bis(trifluoromethyl)be
nzamide (400mg, 0.987mmol) in EtOH (10 mL) were added NaOAc (0.162g, 1.97mmol) and MeONH 2 . HCl (0.082g, 0.987mmol) at 20°C. The reaction mixture was stirred for 12h at 50°C, at which time completion was observed by LCMS. The reaction mixture was diluted with H 2 O (10mL) and extracted with EtOAc (3x30mL). The combined organic layers were washed with brine (10mL), dried over Na 2 SO 4 , and concentrated. The residue was purified by chromato- graphic column on silica gel (PE:EtOAc = 100:0 to 82:18) to deliver N-[1-[3-[N-methoxy-C-me- thyl-carbonimidoyl]pyrazin-2-yl]ethyl]-3,5-bis(trifluorometh
yl)benzamide (I-1, 0.258g, 60% yield) as a white solid. 1H-NMR (400MHz, CDCl 3 ) δ = 8.57 (d, J=2.4 Hz, 1H), 8.53 (d, J=2.4 Hz, 1H), 8.01 (s, 1H), 8.26 (s, 2H), 7.66 (br d, J=7.8 Hz, 1H), 6.07 (dq, J=7.8, 6.7 Hz, 1H), 2.36 (s, 3H), 4.12 (s, 3H), 1.65 (d, J=6.50 Hz, 3H). LCMS: 434.12 (calculated); 435.0 (observed). Example 4: preparation of 3-(1-cyanocyclopropyl)-N-(cyclopropylmethyl)-N-[1-[3-(N-meth
oxy- C-methyl-carbonimidoyl)pyrazin-2-yl]ethyl]-5-(trifluoromethy
l)benzamide (I-9) Step 1: preparation of 3-(1-cyanocyclopropyl)-N-(cyclopropylmethyl)-N-[1-[3-(N-meth
oxy-C- methyl-carbonimidoyl)pyrazin-2-yl]ethyl]-5-(trifluoromethyl)
benzamide To a stirred solution of 3-(1-cyanocyclopropyl)-N-[1-[3-(N-methoxy-C-methyl-carbonimi
doyl)py- razin-2-yl]ethyl]-5-(trifluoromethyl)benzamide (150mg, 0.348mmol, prepared via the same syn- thetic route as I-1) in DMF (5mL) was added NaH (28mg, 0.696mmol) in portions at 0°C. The reaction mixture was stirred for 30min at 0°C and then heated to 80°C. A solution of bromo- methylcyclopropane (70mg, 0.522mmol) in DMF (5mL) was added dropwise at 80°C and stirred at this temperature for 12h. The reaction mixture was cooled to RT, quenched with NH 4 Cl (aq. 10mL) and extracted with EtOAc (3x10mL). The combined organic layers were washed with brine (4x5mL), dried over Na 2 SO 4 , filtered and concentrated under reduced pressure. The resi- due was purified by preparative-HPLC (NH 4 HCO 3 ) to deliver 3-(1-cyanocyclopropyl)-N-(cyclo- propylmethyl)-N-[1-[3-(N-methoxy-C-methyl-carbonimidoyl)pyra
zin-2-yl]ethyl]-5-(trifluorome- thyl)benzamide (I-9, 50mg, 15% yield) as a yellow syrup. 1H-NMR (400MHz, CDCl3) δ = 8.64 (d, J=2.45Hz, 1H), 8.61 (d, J=2.45Hz, 1H), 7.64 (s, 1H), 7.46 (s, 1H), 7.42 (s, 1H), 5.96 (br s, 1H), 3,80 (s, 3H), 3.35-3.47 (m, 1H), 3.18-3.28 (m, 1H), 2.10(s, 3H), 1.81-1.85 (m, 2H), 1.69 (d, J=6,97Hz, 3H), 1.59-1.63 (m, 2H), 0.85-0.90 (m, 1H), 0.31-0.43 (m, 2H), 0.13-0.10 (m, 2H). Example 5: preparation of 3-chloro-N (cyclopropylmethyl) 5 (4 fluorophenyl)sulfonyl-N-[1-[3- (N-methoxy-C-methyl-carbonimidoyl)pyrazin-2-yl]ethyl]benzami
de (I-17) Step 1: preparation of 1-(3-chloropyrazin-2-yl)-N-(cyclopropylmethyl)ethanamine To a stirred solution of 1-(3-chloropyrazin-2-yl)ethenone (200mg, 3.2mmol) in THF (20mL) at RT were added cyclopropylmethanamine (109mg, 0.364mmol) and Ti(i-PrO) 4 (364mg; 1.282mmol). The reaction mixture was stirred for 12h at RT and then stirred at 50°C for 4h. TLC (PE:EtOAc=1:1) showed complete conversion. The reaction mixture was cooled to RT, then EtOH (10mL) was added and NaBH 3 CN (121mg, 1.923mmol) was added in portions. TLC (PE:EtOAc=1:1) showed the reaction was completed after 12h at RT. The reaction mixture was quenched with water (30mL), filtered and the filtrate was extracted with EtOAc (3x20mL). The organic layers were washed with brine (20mL), dried over Na 2 SO 4 and concentrated under re- duced pressure. The residue was purified by chromatographic column on silica gel (PE:EtOAc=100:0 to 16:84) to deliver 1-(3-chloropyrazin-2-yl)-N-(cyclopropylmethyl)ethanamine (94mg, 35% yield) as a yellow syrup. 1H-NMR (400MHz, CDCl3) δ = 8.50 (d, J=2.38 Hz,1H), 8.25 (d, J=2.38HZ, 1H), 4.37 (q, J=6.65Hz, 1H), 2.51 (dd, J=11.73, 6.21Hz, 1H), 2.05 (dd, J=11.67, 7.53Hz, 1H), 1.38 (d, J=6.65Hz,3H), 0.83-1.00 (m, 1H), 0.43 (td, J=7.87, 2.45Hz, 2H), 0.06-0.14 (m, 2H). Step 2: preparation of 3-chloro-N-[1-(3-chloropyrazin-2-yl)ethyl]-N-(cyclopropylmet
hyl)-5-(4- fluorophenyl)sulfonyl-benzamide To a stirred solution of 3-chloro-5-(4-fluorophenyl)sulfonyl-benzoic acid (100mg, 0.318mmol) in ACN (5mL) were added chloro-N,N,N′,N′-tetramethylformamidinium-hexafluorophos
phate (134mg, 0.477mmol), N-methylimidazole (78mg; 0.995mmol) and 1-(3-chloropyrazin-2-yl)-N- (cyclopropylmethyl)ethanamine (81mg, 0.382mmol) at RT. LC-MS showed the reaction was completed after 12h. The reaction mixture was quenched with water (10mL) and extracted with EtOAc (3x8mL). The combined organic layers were washed with brine (10mL) dried over Na 2 SO 4 , filtered and concentrated under reduced pressure. The residue was purified by prepar- ative TLC (PE:EtOAc=1:1) to deliver 3-chloro-N-[1-(3-chloropyrazin-2-yl)ethyl]-N-(cyclopropyl- methyl)-5-(4-fluorophenyl)sulfonyl-benzamide (50mg, 31% yield) as a yellow oil. 1H-NMR (400MHz, CDCl3) δ = 8.51 (d, J=2.38Hz, 1H), 8.27 (d, J=2.38Hz, 1H), 7.94-8.00 (m, 2H), 7.88 (br s, 1H), 7.61 (s, 1H), 7.23 (br t, J=8.50Hz, 2H), 4.42 (q, J=6.71Hz, 1H), 2.56 (dd, J=11.76, 6.25Hz, 1H), 2.09-2.13 (m, 1H), 1.43 (d, J=6.63Hz, 3H), 0.93-0.98 (m, 1H), 0.44-0.48 (m, 2H), 0.21-0.33 (m, 1H), 0.05-0.10 (m, 1H). Step 3: preparation of 3-chloro-N-(cyclopropylmethyl)-N-[1-[3-(1-ethoxyvinyl)pyrazi
n-2- yl]ethyl]-5-(4-fluorophenyl)sulfonyl-benzamide To a stirred solution of 3-chloro-N-[1 (3 chloropyrazin 2 yl)ethyl] N (cyclopropylmethyl)-5-(4- fluorophenyl)sulfonyl-benzamide (300mg, 0.662mmol) in toluene (8mL) were added tributyl(1- ethoxyvinyl)stannane (287mg, 0.795mmol) and Pd(PPh 3 ) 2 Cl 2 (100mg, cat.) at RT. The sealed vial was irradiated in the microwave for 1h at 130°C. TLC (PE:EtOAc=3:1) showed the reaction was completed. The reaction mixture was concentrated under reduced pressure. The residue was diluted with aq. KF (10mL) and stirred for 30min. The reaction mixture was filtered through a celite pad and the filtrate was extracted with EtOAc (3x30mL). The combined organic layers were washed with brine (6ml), dried over Na 2 SO 4 , filtered and concentrated under reduced pressure to deliver 3-chloro-N-(cyclopropylmethyl)-N-[1-[3-(1-ethoxyvinyl)pyrazi
n-2-yl]ethyl]-5- (4-fluorophenyl)sulfonyl-benzamide (4.3g, crude) as a yellow oil. The crude product was em- ployed in the next step without further purification. Step 4: preparation of N-[1-(3-acetylpyrazin-2-yl)ethyl]-3-chloro-N-(cyclopropylmet
hyl)-5-(4- fluorophenyl)sulfonyl-benzamide To a stirred solution of 3-chloro-N-(cyclopropylmethyl)-N-[1-[3-(1-ethoxyvinyl)pyrazi
n-2- yl]ethyl]-5-(4-fluorophenyl)sulfonyl-benzamide (1.3g, 2.39mmol) in THF (20mL) was added HCl (aq., 2N, 10mL) at RT. The reaction mixture was stirred for 4h at RT. TLC (PE:EtOAc=1:1) showed the reaction was completed. The reaction mixture was diluted with water (10mL) and extracted with EtOAc (3x20mL). The combined organic layers were washed with brine (10mL), dried over Na 2 SO 4 , filtered and concentrated under reduced pressure. The residue was purified by chromatographic column on silica gel (PE:EtOAc=100:0 to 35:65) to deliver N-[1-(3-acetylpy- razin-2-yl)ethyl]-3-chloro-N-(cyclopropylmethyl)-5-(4-fluoro
phenyl)sulfonyl-benzamide (500mg, 70% yield) as a yellow solid. Step 5: preparation of 3-chloro-N-(cyclopropylmethyl)-5-(4-fluorophenyl)sulfonyl-N-
[1-[3-(N- methoxy-C-methyl-carbonimidoyl)pyrazin-2-yl]ethyl]benzamide To a stirred solution of N-[1-(3-acetylpyrazin-2-yl)ethyl]-3-chloro-N-(cyclopropylmet
hyl)-5-(4- fluorophenyl)sulfonyl-benzamide (500mg, 0.971mmol) in EtOH (5mL) were added NaOAc (159mg, 1.94mmol) and O-methylhydroxylamine hydrochloride (122mg, 1.45mmol) at RT. The reaction mixture was heated to 50°C and stirred for 12h. LC-MS showed the reaction was com- pleted. The reaction mixture was concentrated under reduced pressure, quenched with water (10ml) and extracted with EtOAc (3x10mL). The combined organic layers were washed with brine (5mL), dried over Na 2 SO 4 , filtered and concentrated under reduced, pressure. The residue was purified by chromatographic column on silica gel (PE:EtOAc=100:0 to 50:50) to deliver 3- chloro-N-(cyclopropylmethyl)-5-(4-fluorophenyl)sulfonyl-N-[1
-[3-(N-methoxy-C-methyl-carbon- imidoyl)pyrazin-2-yl]ethyl]benzamide (I-17, 268mg, 51% yield) as a yellow solid. 1H-NMR (400MHz, CDCl3) δ =8.64 (s, 1H), 8.61 (s, 1H), 8.038.09 (m, 3H), 7.64 (br s, 1H), 7.58 (s, 1H), 7.45 (br t, J=8.58Hz, 2H), 5.94 (br d, J=1.91Hz, 1H), 3.73 (br s, 3H), 3.13-3.42 (m, 2H), 2.03-2.14 (m, 3H), 1.65 (br d, J=6.79Hz, 3H), 0.65-0.97 (m, 1H), 0.23-0.41 (m, 2H), -0.28-0.09 (m, 2H). Example 6 preparation of N-[1-[3-(N-ethyl-N'-hydroxy-N-methyl-carbamimidoyl)pyrazin-2
- yl]ethyl]-3,5-bis(trifluoromethyl)benzamide (I-170) Step 1: preparation of 3-[1-[[3,5-bis(trifluoromethyl)benzoyl]amino]ethyl]-N-hydrox
y-pyrazine-2- carboximidoyl chloride To a stirred solution of N-[1-[3-(N'-hydroxycarbamimidoyl)pyrazin-2-yl]ethyl]-3,5-bis
(trifluoro- methyl)benzamide (3g, 7.1mmol) in HCl (aq., 6N, 30mL) at 0°C was added dropwise a solution of NaNO 2 (735mg, 10.6mmol) in water (2mL). The reaction mixture was stirred for 3h at RT. LC- MS showed the reaction was completed. The reaction mixture was extracted with EtOAc (3x50mL). The combined organic layers were dried over Na 2 SO 4 , filtered and concentrated un- der reduced pressure to deliver 3-[1-[[3,5-bis(trifluoromethyl)benzoyl]amino]ethyl]-N-hydrox
y- pyrazine-2-carboximidoyl chloride (3g, crude) as a yellow solid. The crude product was em- ployed in the next step without further purification Step 2: preparation of N-[1-[3-(N-ethyl-N'-hydroxy-N-methyl-carbamimidoyl)pyrazin-2
-yl]ethyl]- 3,5-bis(trifluoromethyl)benzamide To a stirred solution of 3-[1-[[3,5-bis(trifluoromethyl)benzoyl]amino]ethyl]-N-hydrox
y-pyrazine- 2-carboximidoyl chloride (500mg, 1.1mmol) in THF (10mL) was added dropwise N-methyleth- anamine (80mg, 1.4mmol) at RT. The reaction mixture was stirred for 16h at RT under N 2 at- mosphere. TLC (PE:EtOAc=1:1) showed the reaction was completed. The reaction mixture was concentrated under reduced pressure and the crude was purified by chromatographic column on silica gel (PE:EtOAc=1:1) to deliver N-[1-[3-(N-ethyl-N'-hydroxy-N-methyl-carbamimidoyl)py- razin-2-yl]ethyl]-3,5-bis(trifluoromethyl)benzamide (I-170, 300mg, 59% yield) as a yellow syrup. 1H-NMR (400MHz, CDCl3) δ = 8.86 (d, J=1.63Hz, 1H), 8.74 (s, 1H), 8.47 (s, 2H), 8.18 (s, 1H), 5.26-5.47 (m, 1H), 3.37 (br d, J=7.25Hz, 2H), 1.72 (d, J=6.88Hz, 3H), 1.27 (t, J=7.13Hz, 3H). With appropriate modification of the starting materials, the procedures given in the synthesis descriptions were used to obtain further compounds I. The compounds obtained in this manner are listed in the table that follows, together with physical data. Biological examples If not otherwise specified, the test solutions were prepared as follow: The active compound was dissolved at the desired concentration in a mixture of 1:1 (vol:vol) distilled water : acetone. The test solution was prepared on the day of use. The activity of the compounds of formula I of the present invention can be demonstrated and evaluated by the following biological tests. B.1 Green Peach Aphid (Myzus persicae) For evaluating control of green peach aphid (Myzus persicae) through systemic means, the test unit consisted of 96-well-microtiter plates containing liquid artificial diet under an artificial mem brane. The compounds were formulated using a solution containing 75% v/v water and 25% v/v DMSO. Different concentrations of formulated compounds were pipetted into the aphid diet, us- ing a custom built pipetter, at two replications. After application, 5 - 8 adult aphids were placed on the artificial membrane inside the microtiter plate wells. The aphids were then allowed to suck on the treated aphid diet and incubated at about 23 ± 1°C and about 50 ± 5 % relative humidity for 3 days. Aphid mortality and fecundity was then visually assessed. In this test, compounds I-3, I-4, I-5, I-7, I-8, I-9, I-12, I-13, I-14, I-15, I-18, I-19, I-21, I-35, I-50, I-83, I-93, I-99, I-120, I-121, I-123, I-126, I-127, I-130, I-131, I-132, I-152, I-159, I-169, I-170, I- 174, I-176, and I-180, resp., at 2500 ppm showed at least 75% mortality in comparison with un- treated controls. B.2 Tobacco budworm (Heliothis virescens) For evaluating control of tobacco budworm (Heliothis virescens), the test unit consisted of 96- well-microtiter plates containing an insect diet and 15-25 H. virescens eggs. The compounds were formulated using a solution containing 75% v/v water and 25% v/v DMSO. Different concentrations of formulated compounds were sprayed onto the insect diet at 10 µl, using a custom-built micro atomizer, at two replications. After application, microtiter plates were incubated at about 28 ± 1°C and about 80 ± 5 % rela- tive humidity for 5 days. Egg and larval mortality was then visually assessed. In this test, compounds I-1, I-3, I-5, I-7, I-10, I-11, I-12, I-13, I-14, I-15, I-16, I-19, I-21, I-22, I- 23, I-24, I-30, I-33, I-35, I-53, I-61, I-64, I-75, I-76, I-77, I-78, I-81, I-82, I-83, I-87, I-89, I-90, I-92, I-93, I-95, I-102, I-105, I-111, I-112, I-113, I-114, I-120, I-121, I-123, I-125, I-127, I-129, I-130, I- 131, I-133, I-136, I-140, I-144, I-148, I-150, I-151, I-155, I-157, I-158, I-159, I-167, I-169, I-170, I-171, I-172, I-174, I-180, and I-181, resp., at 2500 ppm showed at least 75% mortality in com- parison with untreated controls. B.3 Boll weevil (Anthonomus grandis) For evaluating control of boll weevil (Anthonomus grandis), the test unit consisted of 96-well- microtiter plates containing an insect diet and 5-10 A. grandis eggs. The compounds were formulated using a solution containing 75% v/v water and 25% v/v DMSO. Different concentrations of formulated compounds were sprayed onto the insect diet at 5 µl, using a custom-built micro atomizer, at two replications. After application, microtiter plates were incubated at about 25 ± 1°C and about 75 ± 5 % rela- tive humidity for 5 days. Egg and larval mortality was then visually assessed. In this test, compounds I-1, I-3, I-4, I-5, I-7, I-8, I-10, I-11, I-12, I-13, I-14, I-15, I-16, I-17, I-18, I-19, I-21, I-22, I-23, I-24, I-30, I-34, I-35, I-39, I-40, I-41, I-46, I-48, I-50, I-53, I-58, I-59, I-60, I- 61, I-64, I-71, I-74, I-75, I-76, I-78, I-83, I-85, I-87, I-88, I-89, I-90, I-93, I-95, I-99, I-102, I-103, I- 104, I-107, I-108, I-111, I-112, I-114, I-115, I-117, I-118, I-120, I-121, I-122, I-123, I-125, I-126, I-127, I-128, I-129, I-130, I-131, I-132, I-133, I-134, I-135, I-136, I-140, I-142, I-144, I-147, I-148, I-150, I-155, I-157, I-158, I-159, I-160, I-162, I-167, I-169, I-170, I-171, I-172, I-174, I-176, I-179, I-180, I-181, I-183, I-184, and I-188, resp., at 2500 ppm showed at least 75% mortality in com- parison with untreated controls. B.4. Southern armyworm (Spodoptera eridania), 2nd instar larvae The active compounds were formulated by a Tecan liquid handler in 100% cyclohexanone as a 10,000-ppm solution supplied in tubes. The 10,000-ppm solution was serially diluted in 100% cyclohexanone to make interim solutions. These served as stock solutions for which final dilu- tions were made by the Tecan in 50% acetone:50% water (v/v) into 10 or 20ml glass vials. A non-ionic surfactant (Kinetic®) was included in the solution at a volume of 0.01% (v/v). The vials were then inserted into an automated electrostatic sprayer equipped with an atomizing nozzle for application to plants/insects. Lima bean plants (variety Sieva) were grown 2 plants to a pot and selected for treatment at the 1st true leaf stage. Test solutions were sprayed onto the foli- age by an auto-mated electrostatic plant sprayer equipped with an atomizing spray nozzle. The plants were dried in the sprayer fume hood and then removed from the sprayer. Each pot was placed into perforated plastic bags with a zip closure. Ten to 11 armyworm larvae were placed into the bag and the bags zipped closed. Test plants were maintained in a growth room at about 25ºC and about 20-40% relative humidity for 4 days, avoiding direct exposure to fluorescent light (14:10 light:dark photoperiod) to prevent trapping of heat inside the bags. Mortality and re- duced feeding were assessed 4 days after treatment, compared to untreated control plants. In this test, compounds I-1, I-4, I-5, I-7, I-9, I-10, I-11, I-12, I-13, I-14, I-15, I-16, I-17, I-18, I-19, I-21, I-22, I-23, I-24, I-30, I-41, I-46, I-47, I-57, I-64, I-75, I-76, I-77, I-78, I-81, I-82, I-83, I-87, I- 89, I-93, I-95, I-100, I-102, I-103, I-104, I-106, I-107, I-111, I-112, I-113, I-114, I-115, I-120, I- 121, I-122, I-123, I-125, I-126, I-127, I-128, I-129, I-130, I-131, I-133, I-134, I-135, I-136, I-139, I-140, I-144, I-145, I-148, I-150, I-151, I-155, I 156, I 157, I 159, I-167, I-171, and I-172, resp., at 300 ppm at least 75 % mortality in comparison with untreated controls. B.5 Yellow fever mosquito (Aedes aegypti) For evaluating control of yellow fever mosquito (Aedes aegypti) the test unit consisted of 96- well-microtiter plates containing 200µl of tap water per well and 5-15 freshly hatched A. aegypti larvae. The active compounds were formulated using a solution containing 75% (v/v) water and 25% (v/v) DMSO. Different concentrations of formulated compounds or mixtures were sprayed onto the insect diet at 2.5µl, using a custom-built micro atomizer, at two replications. After application, microtiter plates were incubated at 28 ± 1°C, 80 ± 5 % RH for 2 days. Larval mortality was then visually assessed. In this test, compounds I-1, I-2, I-3, I-4, I-5, I-7, I-8, I-9, I-10, I-11, I-12, I-13, I-14, I-15, I-16, I- 17, I-18, I-19, I-21, I-22, I-23, I-24, I-25, I-26, I-30, I-33, I-35, I-38, I-39, I-40, I-41, I-42, I-43, I-44, I-46, I-47, I-48, I-49, I-50, I-51, I-55, I-56, I-57, I-59, I-62, I-64, I-69, I-70, I-71, I-74, I-75, I-76, I- 77, I-78, I-79, I-81, I-82, I-83, I-85, I-87, I-90, I-91, I-92, I-93, I-94, I-95, I-97, I-99, I-100, I-102, I- 103, I-104, I-105, I-107, I-111, I-112, I-113, I-114, I-115, I-117, I-118, I-119, I-120, I-121, I-122, I-123, I-124, I-125, I-126, I-127, I-128, I-129, I-130, I-131, I-132, I-133, I-134, I-135, I-136, I-140, I-144, I-145, I-148, I-150, I-151, I-153, I-154, I-155, I-157, I-158, I-159, I-160, I-161, I-163, I-167, I-169, I-170, I-171, I-172, I-173, I-174, I-176, I-180, I-181, I-183, I-186, and I-187, resp., at 2500 ppm showed at least 75% mortality in comparison with untreated controls.
