PYRIDONE COMPOUND AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND USE - CHINA AUSTRALIA INST OF TRANSLATIONAL MEDICINE CO LTD NANJING

Title:

PYRIDONE COMPOUND AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND USE

Document Type and Number:

WIPO Patent Application WO/2024/098890

Kind Code:

A1

Abstract:

A pyridone compound and a preparation method therefor, a pharmaceutical composition and a use. The structure of the pyridone compound is as shown in formula (I), and the pyridone compound comprises an isomer, a pharmaceutically acceptable salt, or a mixture thereof. The pyridone compound has a highly effective inhibitory effect on cIAP1, cIAP2, XIAP and various tumor cells, and can be used to prepare anti-tumor drugs that can exert pharmacological effects at both the molecular level and the cellular level.

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Inventors:

ZHANG MING (CN)
ZHAN JING (CN)
LIU TINGTING (CN)
SHI GUANGYI (CN)
ZHENG XIUQIN (CN)
CHEN PANHAI (CN)

Application Number:

PCT/CN2023/115159

Publication Date:

May 16, 2024

Filing Date:

August 28, 2023

Export Citation:

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Assignee:

CHINA AUSTRALIA INST OF TRANSLATIONAL MEDICINE CO LTD NANJING (CN)

International Classes:

C07D401/06; A61K31/496; A61P35/00; C07D471/04; C07D471/10

Attorney, Agent or Firm:

NANJING TIANHUA PATENT AGENT CO., LTD. (CN)

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