Title:
PYRIDONE OR PYRIMIDONE DERIVATIVE AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/155830
Kind Code:
A1
Abstract:
Disclosed in the present invention are a pyridone or pyrimidone derivative and an application thereof, and particularly disclosed are a compound as shown in formula (VI) and a pharmaceutically acceptable salt thereof.
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Inventors:
CHEN SHUHUI (CN)
FENG JIAJIE (CN)
WANG ZHENG (CN)
LI PENG (CN)
HE HAIYING (CN)
FENG JIAJIE (CN)
WANG ZHENG (CN)
LI PENG (CN)
HE HAIYING (CN)
Application Number:
PCT/CN2023/076449
Publication Date:
August 24, 2023
Filing Date:
February 16, 2023
Export Citation:
Assignee:
MEDSHINE DISCOVERY INC (CN)
International Classes:
C07D401/14; A61K31/506; A61K31/53; A61P31/14; A61P43/00; C07D401/06; C07D495/04
Domestic Patent References:
| WO2022035911A2 | 2022-02-17 |
Other References:
MCKIMM-BRESCHKIN JENNIFER L.; HAY ALAN J.; CAO BIN; COX REBECCA J.; DUNNING JAKE; MOEN ANN C.; OLSON DANIEL; PIZZORNO ANDRÉS; HAYD: "COVID-19, Influenza and RSV: Surveillance-informed prevention and treatment – Meeting report from an isirv-WHO virtual conference", ANTIVIRAL RESEARCH, ELSEVIER BV, NL, vol. 197, 18 December 2021 (2021-12-18), NL , XP086916600, ISSN: 0166-3542, DOI: 10.1016/j.antiviral.2021.105227
UNOH YUTO, UEHARA SHOTA, NAKAHARA KENJI, NOBORI HARUAKI, YAMATSU YUKIKO, YAMAMOTO SHIHO, MARUYAMA YUKI, TAODA YOSHIYUKI, KASAMATSU: "Discovery of S-217622, a Non-Covalent Oral SARS-CoV-2 3CL Protease Inhibitor Clinical Candidate for Treating COVID-19", BIORXIV, 26 January 2022 (2022-01-26), pages 1 - 52, XP093086254, DOI: 10.1101/2022.01.26.477782
SASAKI MICHIHITO, TABATA KOSHIRO, KISHIMOTO MAI, ITAKURA YUKARI, KOBAYASHI HIROKO, ARIIZUMI TAKUMA, UEMURA KENTARO, TOBA SHINSUKE,: "Oral administration of S-217622, a SARS-CoV-2 main protease inhibitor, decreases viral load and accelerates recovery from clinical aspects of COVID-19", BIORXIV, 15 February 2022 (2022-02-15), pages 1 - 51, XP093086255, DOI: 10.1101/2022.02.14.480338
UNOH YUTO, UEHARA SHOTA, NAKAHARA KENJI, NOBORI HARUAKI, YAMATSU YUKIKO, YAMAMOTO SHIHO, MARUYAMA YUKI, TAODA YOSHIYUKI, KASAMATSU: "Discovery of S-217622, a Non-Covalent Oral SARS-CoV-2 3CL Protease Inhibitor Clinical Candidate for Treating COVID-19", BIORXIV, 26 January 2022 (2022-01-26), pages 1 - 52, XP093086254, DOI: 10.1101/2022.01.26.477782
SASAKI MICHIHITO, TABATA KOSHIRO, KISHIMOTO MAI, ITAKURA YUKARI, KOBAYASHI HIROKO, ARIIZUMI TAKUMA, UEMURA KENTARO, TOBA SHINSUKE,: "Oral administration of S-217622, a SARS-CoV-2 main protease inhibitor, decreases viral load and accelerates recovery from clinical aspects of COVID-19", BIORXIV, 15 February 2022 (2022-02-15), pages 1 - 51, XP093086255, DOI: 10.1101/2022.02.14.480338
Attorney, Agent or Firm:
LIU , SHEN & ASSOCIATES (CN)
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