Title:
PYRIMIDINEDIONE COMPOUND CONTAINING SATURATED OXYGEN-CONTAINING HETEROCYCLIC GROUP AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/067566
Kind Code:
A1
Abstract:
A pyrimidinedione compound containing a saturated oxygen-containing heterocyclic group and the use thereof, and a pharmaceutical composition comprising such compounds, which can be used as a gonadotropin releasing hormone receptor antagonist. The present invention also relates to a method for preparing such compounds and the pharmaceutical composition, and the use thereof in the prevention or treatment of sex hormone dependent diseases, including, but not limited to, prostate cancer, endometriosis, hysteromyoma, precocious puberty and other diseases.
Inventors:
JIN CHUANFEI (CN)
ZHONG WENHE (CN)
ZHU JUNLING (CN)
YU TIANXI (CN)
ZHOU KEJUN (CN)
ZHONG WENHE (CN)
ZHU JUNLING (CN)
YU TIANXI (CN)
ZHOU KEJUN (CN)
Application Number:
PCT/CN2020/119029
Publication Date:
April 07, 2022
Filing Date:
September 29, 2020
Export Citation:
Assignee:
SUNSHINE LAKE PHARMA CO LTD (CN)
International Classes:
C07D495/04; A61K31/519; A61P1/00; A61P13/08; A61P15/00; A61P15/08; A61P15/12; A61P17/10; A61P17/14; A61P25/28; A61P35/00; A61P35/04
Domestic Patent References:
| WO2019020102A1 | 2019-01-31 |
Foreign References:
| EP1479684A1 | 2004-11-24 | |||
| CN1146206A | 1997-03-26 | |||
| CN1173868A | 1998-02-18 | |||
| EP2329823A1 | 2011-06-08 | |||
| EP1495768A1 | 2005-01-12 |
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