Title:
PYRIPYROPENE A BIOSYNTHETIC GENE
Document Type and Number:
WIPO Patent Application WO/2010/010955
Kind Code:
A1
Abstract:
Disclosed are an isolated novel polynucleotide containing a nucleotide sequence for coding at least one type of polypeptide that contributes to the biosynthesis of pyripyropene A, a recombinant vector containing said polynucleotide, and a transfectant containing said polynucleotide. The invention provides a pyripyropene A biosynthetic gene that is useful for the production of a novel pyripyropene analog, the improvement of pyripyropene A microorganism productivity, the manufacture of a microbial insecticide, and the creation of insect-resistant plants.
Inventors:
ANZAI HIROYUKI (JP)
YAMAMOTO KENTARO (JP)
TSUCHIDA MARIKO (JP)
OYAMA KAZUHIKO (JP)
MITOMI MASAAKI (JP)
YAMAMOTO KENTARO (JP)
TSUCHIDA MARIKO (JP)
OYAMA KAZUHIKO (JP)
MITOMI MASAAKI (JP)
Application Number:
PCT/JP2009/063293
Publication Date:
January 28, 2010
Filing Date:
July 24, 2009
Export Citation:
Assignee:
MEIJI SEIKA KAISHA (JP)
ANZAI HIROYUKI (JP)
YAMAMOTO KENTARO (JP)
TSUCHIDA MARIKO (JP)
OYAMA KAZUHIKO (JP)
MITOMI MASAAKI (JP)
ANZAI HIROYUKI (JP)
YAMAMOTO KENTARO (JP)
TSUCHIDA MARIKO (JP)
OYAMA KAZUHIKO (JP)
MITOMI MASAAKI (JP)
International Classes:
C12N15/09; C12N1/15; C12N1/21; C12P17/18
Domestic Patent References:
| WO1994009147A1 | 1994-04-28 | |||
| WO2004060065A1 | 2004-07-22 | |||
| WO2006129714A1 | 2006-12-07 | |||
| WO2008066153A1 | 2008-06-05 | |||
| WO2009022702A1 | 2009-02-19 |
Foreign References:
| JP2008500997A | 2008-01-17 | |||
| JP2008190862A | 2008-08-21 | |||
| JP2008270294A | 2008-11-06 | |||
| JP2009020591A | 2009-01-29 | |||
| JPH04360895A | 1992-12-14 | |||
| JPH06184158A | 1994-07-05 | |||
| JPH08239385A | 1996-09-17 | |||
| JPH08259569A | 1996-10-08 | |||
| JPH08269062A | 1996-10-15 | |||
| JPH08269063A | 1996-10-15 | |||
| JPH08269064A | 1996-10-15 | |||
| JPH08269065A | 1996-10-15 | |||
| JPH08269066A | 1996-10-15 | |||
| JPH08291164A | 1996-11-05 | |||
| US0500997A | 1893-07-04 | |||
| US5597835A | 1997-01-28 |
Other References:
FEDOROVA, N.D. ET AL.: "Genomic islands in the pathogenic filamentous fungus Aspergillus fumigatus", PLOS GENET., vol. 4, no. 4, 11 April 2008 (2008-04-11), pages E1000046, XP002544950
NIERMAN, W.C. ET AL.: "Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus", NATURE, vol. 438, no. 7071, 2005, pages 1151 - 1156, XP008139207
TOMODA, H. ET AL.: "Biosynthesis of Pyripyropene A", J.ORG.CHEM., vol. 61, no. 3, 1996, pages 882 - 886, XP008139912
SUNAZUKA, T. ET AL.: "Total synthesis of alpha- pyrone meroterpenoids, novel bioactive microbial metabolites", CHEM.REV., vol. 105, no. 12, 2005, pages 4559 - 4580, XP008139913
JOURNAL OF ANTIBIOTICS, vol. 46, no. 7, 1993, pages 1168 - 9
JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY, JAPAN, vol. 56, no. 6, 1998, pages 478 - 488
JOURNAL OF ANTIBIOTICS, vol. 50, no. 3, 1997, pages 229 - 36
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, vol. 61, no. 12, 1995, pages 4429 - 35
EUPENICILLIUM RETICULOSPORUM NRRL-3446 STRAIN IS IN APPLIED AND ENVIRONMENTAL MICROBIOLOGY, vol. 61, no. 12, 1995, pages 4429 - 35
JOURNAL OF ORGANIC CHEMISTRY, vol. 61, 1996, pages 882 - 886
CHEMICAL REVIEW, vol. 105, 2005, pages 4559 - 4580
IKADA; OHMURA, PROTEIN, NUCLEIC ACID AND ENZYME, vol. 43, 1998, pages 1265 - 1277
CARRERAS, C.W.; SANTI, D.V., "CURRENT OPINION IN BIOTECHNOLOGY", (UK), vol. 9, 1998, pages 403 - 411
HUTCHINSON, C. R., "CURRENT OPINION IN MICROBIOLOGY", (UK), vol. 1, 1998, pages 319 - 329
KATZ, L.; MCDANIEL, R., "MEDICINAL RESEARCH REVIEWS", (USA), vol. 19, 1999, pages 543 - 558
HUTCHINSON, C. R., "BIO/TECHNOLOGY", (USA), vol. 12, 1994, pages 375 - 380
SAMBROOK, J. ET AL.: ""Molecular cloning: a laboratory manual", (USA)", 1989, COLD SPRING HARBOR LABORATORY
TETRAHEDRON LETTERS, vol. 37, no. 36, 1996, pages 6461 - 6464
J. ANTIBIOTICS, vol. 49, 1996, pages 292 - 298
See also references of EP 2319923A4
NIERMAN, W.C. ET AL.: "Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus", NATURE, vol. 438, no. 7071, 2005, pages 1151 - 1156, XP008139207
TOMODA, H. ET AL.: "Biosynthesis of Pyripyropene A", J.ORG.CHEM., vol. 61, no. 3, 1996, pages 882 - 886, XP008139912
SUNAZUKA, T. ET AL.: "Total synthesis of alpha- pyrone meroterpenoids, novel bioactive microbial metabolites", CHEM.REV., vol. 105, no. 12, 2005, pages 4559 - 4580, XP008139913
JOURNAL OF ANTIBIOTICS, vol. 46, no. 7, 1993, pages 1168 - 9
JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY, JAPAN, vol. 56, no. 6, 1998, pages 478 - 488
JOURNAL OF ANTIBIOTICS, vol. 50, no. 3, 1997, pages 229 - 36
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, vol. 61, no. 12, 1995, pages 4429 - 35
EUPENICILLIUM RETICULOSPORUM NRRL-3446 STRAIN IS IN APPLIED AND ENVIRONMENTAL MICROBIOLOGY, vol. 61, no. 12, 1995, pages 4429 - 35
JOURNAL OF ORGANIC CHEMISTRY, vol. 61, 1996, pages 882 - 886
CHEMICAL REVIEW, vol. 105, 2005, pages 4559 - 4580
IKADA; OHMURA, PROTEIN, NUCLEIC ACID AND ENZYME, vol. 43, 1998, pages 1265 - 1277
CARRERAS, C.W.; SANTI, D.V., "CURRENT OPINION IN BIOTECHNOLOGY", (UK), vol. 9, 1998, pages 403 - 411
HUTCHINSON, C. R., "CURRENT OPINION IN MICROBIOLOGY", (UK), vol. 1, 1998, pages 319 - 329
KATZ, L.; MCDANIEL, R., "MEDICINAL RESEARCH REVIEWS", (USA), vol. 19, 1999, pages 543 - 558
HUTCHINSON, C. R., "BIO/TECHNOLOGY", (USA), vol. 12, 1994, pages 375 - 380
SAMBROOK, J. ET AL.: ""Molecular cloning: a laboratory manual", (USA)", 1989, COLD SPRING HARBOR LABORATORY
TETRAHEDRON LETTERS, vol. 37, no. 36, 1996, pages 6461 - 6464
J. ANTIBIOTICS, vol. 49, 1996, pages 292 - 298
See also references of EP 2319923A4
Attorney, Agent or Firm:
YOSHITAKE, Kenji et al. (JP)
Kenji Yoshitake (JP)
Kenji Yoshitake (JP)
Download PDF: