Title:
PYRROLE-2-FORMAMIDE COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATIONS THEREOF
Document Type and Number:
WIPO Patent Application WO/2019/042267
Kind Code:
A1
Abstract:
Disclosed in the present invention are a pyrrole-2-formamide compound, a preparation method therefor, a pharmaceutical composition thereof, and application thereof in the preparation of drugs for treating or preventing infective diseases caused by mycobacterium tuberculosis. Specifically, the present invention relates to a compound represented in formula (I), a pharmaceutically acceptable salt thereof and a pharmaceutical composition comprising the component in the present invention, R1 and R2 being shown in the specifications. The present invention aims at preparing a new compound for resisting against the activity of mycobacterium tuberculosis; and as a new potential drug, the compound can be used for overcoming the problems related to drug resistance of mycobacterium tuberculosis.
Inventors:
HUANG HAIHONG (CN)
ZHANG DONGFENG (CN)
GAO YONGXIN (CN)
LIN ZIYUN (CN)
ZHAO HONGYI (CN)
GAO MENG (CN)
MA CHEN (CN)
LI YAN (CN)
SHENG LI (CN)
ZHANG DONGFENG (CN)
GAO YONGXIN (CN)
LIN ZIYUN (CN)
ZHAO HONGYI (CN)
GAO MENG (CN)
MA CHEN (CN)
LI YAN (CN)
SHENG LI (CN)
Application Number:
PCT/CN2018/102618
Publication Date:
March 07, 2019
Filing Date:
August 28, 2018
Export Citation:
Assignee:
INST MATERIA MEDICA CAMS (CN)
International Classes:
C07D207/30; A61K31/402; A61K31/4025; A61P31/04; A61P31/06; C07D401/02; C07D403/02; C07D471/02
Foreign References:
| CN105820163A | 2016-08-03 | |||
| CN103596958A | 2014-02-19 | |||
| CN102503891A | 2012-06-20 |
Download PDF: